Blar i Institutt for klinisk og molekylær medisin på tittel

Viser treff 1090-1109 av 3426

    • Excision of the doubly methylated base N4,5-dimethylcytosine from DNA by Escherichia coli Nei and Fpg proteins 

      Alexeeva, Marina; Guragain, Prashanna; Tesfahun, Almaz Nigatu; Tomkuvienė, Miglė; Arshad, Aysha; Gerasimaitė, Rūta; Rukšėnaitė, Audronė; Urbanavičiūtė, Giedrė; Bjørås, Magnar; Lærdahl, Jon Kristen; Klungland, Arne; Klimašauskas, Saulius; Bjelland, Svein (Journal article; Peer reviewed, 2018)
      Cytosine (C) in DNA is often modified to 5-methylcytosine (m5C) to execute important cellular functions. Despite the significance of m5C for epigenetic regulation in mammals, damage to m5C has received little attention. ...

    • Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: A systematic review and meta-analysis 

      Bye, Asta; Sandmæl, Jon Arne; Stene, Guro Birgitte; Thorsen, Lene; Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Pripp, Are Hugo; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)
      The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ...

    • Exercise During Pregnancy 

      Stafne, Signe Nilssen (Doktoravhandlinger ved NTNU, 1503-8181; 2012:144, Doctoral thesis, 2012)
      Friske gravide anbefales å trene regelmessig under svangerskapet for å fortsette å oppnå de samme helsegevinstene som ved trening i ikke-gravid tilstand. Når det gjelder forebygging og behandling av svangerskapsrelaterte ...

    • Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1 

      Morland, Cecilie; Andersson, Krister; Haugen, Øyvind Pernell; Hadzic, Alena; Kleppa, Liv; Gille, Andreas; Rinholm, Johanne Egge; Palibrk, Vuk; Diget, Elisabeth Holm; Kennedy, Lauritz Hagen; Stølen, Tomas; Hennestad, Eivind; Moldestad, Olve; Cai, Yiqing; Puchades, Maja Amedjkouh; Offermanns, Stefan; Vervaeke, Koen Gerard Alois; Bjørås, Magnar; Wisløff, Ulrik; Storm-Mathisen, Jon; Bergersen, Linda Hildegard (Journal article; Peer reviewed, 2017)
      Physical exercise can improve brain function and delay neurodegeneration; however, the initial signal from muscle to brain is unknown. Here we show that the lactate receptor (HCAR1) is highly enriched in pial fibroblast-like ...

    • Exercise prior to assisted fertilization in overweight and obese women (FertilEx): study protocol for a randomized controlled trial 

      Lundgren, Kari Margrethe; Romundstad, Liv Bente; Düring, Vidar Von; Mørkved, Siv; Kjøtrød, Sigrun Beate; Moholdt, Trine Tegdan (Journal article; Peer reviewed, 2016)
      Background Overweight and obese women show reduced conception rates compared to women of normal weight. Insulin resistance and increased amount of visceral fat may be important mechanisms for reduced fertility in these ...

    • Exercise Self-Efficacy and patient global assessment were associated with 6-min walk test distance in persons with rheumatoid arthritis 

      Houge, Ingrid Sæther; Hoff, Mari; Halsan, Oddrun; Videm, Vibeke (Peer reviewed; Journal article, 2022)
      Introduction: Low functional capacity is related to future loss of daily function and cardiovascular events. The present study explored the associations of patient-reported outcome measures (PROMs) and disease-specific ...

    • Exercise training and high-sensitivity cardiac troponin T in patients with heart failure with reduced ejection fraction 

      Koppen, Elias; Omland, Torbjørn; Larsen, Alf Inge; Karlsen, Trine; Linke, Axel; Prescott, Eva Irene Bossano; Halle, Martin; Dalen, Håvard; Delagardelle, Charles; Hole, Torstein; van Craenenbroeck, Emeline M.; Beckers, Paul; Ellingsen, Øyvind; Feiereisen, Patrick; Valborgland, Torstein; Videm, Vibeke (Journal article; Peer reviewed, 2021)
      Plasma cell disorders (PCDs) are identified in the clinical lab by detecting the monoclonal immunoglobulin (M-protein) which they produce. Traditionally, serum protein electrophoresis methods have been utilized to detect ...

    • Exercise training during pregnancy reduces circulating insulin levels in overweight/obese women postpartum: secondary analysis of a randomised controlled trial (the ETIP trial) 

      Garnæs, Kirsti Krohn; Mørkved, Siv; Salvesen, Kjell Å; Salvesen, Øyvind; Moholdt, Trine (Journal article; Peer reviewed, 2018)
      Background The primary aim was to investigate if supervised exercise training during pregnancy could reduce postpartum weight retention (PPWR) three months after delivery in overweight and obese women. We also measured ...

    • Exercise Training in Pregnancy for obese women (ETIP): study protocol for a randomised controlled trial 

      Moholdt, Trine Tegdan; Salvesen, Kjell Å; Ingul, Charlotte Bjørk; Vik, Torstein; Oken, Emily; Mørkved, Siv (Journal article; Peer reviewed, 2011)
      Both maternal pre-pregnancy obesity and excessive gestational weight gain are increasing in prevalence and associated with a number of adverse pregnancy outcomes for both mother and child. Observational studies regarding ...

    • Exercise training reverses cancer-induced oxidative stress and decrease in muscle COPS2/TRIP15/ALIEN 

      Alves, Christiano R. R.; des Neves, Willian; de Almeida, Ney R; Eichelberger, Eric J; Jannig, Paulo R.; Voltarelli, Vanessa A; Tobias, Gabriel C; Bechara, Luiz R G; de Paula Faria, Daniele; Alves, Maria J N; Hagen, Lars; Sharma, Animesh; Slupphaug, Geir; Moreira, Jose Bianco Nascimento; Wisløff, Ulrik; Hirshman, Michael F.; Negrao, Carlos E.; de Castro Jr, Gilberto; Chammas, Roger; Swoboda, Kathryn J.; Ruas, Jorge L.; Goodyear, Laurie J.; Brum, Patricia Chakur (Peer reviewed; Journal article, 2020)
      Objective We tested the hypothesis that exercise training would attenuate metabolic impairment in a model of severe cancer cachexia. Methods We used multiple in vivo and in vitro methods to explore the mechanisms ...

    • Exercised blood plasma promotes hippocampal neurogenesis in the Alzheimer's disease rat brain 

      Norevik, Cecilie Skarstad; Huuha, Aleksi Matias; Røsbjørgen, Ragnhild; Bergersen, Linda Hildegard; Jacobsen, Kamilla; Miguel dos Santos, Rodrigo; Ryan, Liv; Skender, Belma; Bianco Nascimento Moreira, Jose; Kobro-Flatmoen, Asgeir; Witter, Menno Peter; Scrimgeour, Nathan Robert; Rafiee Tari, Atefe (Peer reviewed; Journal article, 2023)
      Background Exercise training promotes brain plasticity and is associated with protection against cognitive impairment and Alzheimer's disease (AD). These beneficial effects may be partly mediated by blood-borne factors. ...

    • Existing data sources in clinical epidemiology: The Scandinavian Thrombosis and Cancer Cohort 

      Jensvoll, Hilde; Severinsen, Marianne T.; Hammerstrøm, Jens; Brækkan, Sigrid Kufaas; Kristensen, Søren R.; Cannegieter, Suzanne C.; Blix, Kristine; Tjønneland, Anne; Rosendaal, Frits Richard; Dziewiecka, Olga; Overvad, Kim; Næss, Inger Anne; Hansen, John-Bjarne (Peer reviewed; Journal article, 2015)
      Background: Although venous thromboembolism (VTE) is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian ...

    • Exome chip analyses in adult attention deficit hyperactivity disorder 

      Zayats, Tetyana; Jacobsen, Kaya Kvarme; Kleppe, Rune; Jacob, CP; Kittel-Schneider, Sarah; Ribases, Marta; Ramos-Quiroga, JA; Richarte, Vanesa; Casas, M; Mota, NR; Grevet, EH; Klein, M; Corominas, J; Bralten, Janita; Galesloot, T; Vasquez, AA; Herms, S; Forstner, AJ; Larsson, H; Breen, G; Asherson, P; Gross-Lesch, Silke; Lesch, KP; Cichon, Sven; Gabrielsen, Maiken Elvestad; Holmen, Oddgeir Lingaas; Bau, CH; Buitelaar, Jan; Kiemeney, L; Faraone, Stephen V.; Cormand, B; Franke, Barbara; Reif, Andreas; Haavik, Jan; Johansson, Stefan (Journal article; Peer reviewed, 2016)
      Attention-deficit/hyperactivity disorder (ADHD) is a highly heritable childhood-onset neuropsychiatric condition, often persisting into adulthood. The genetic architecture of ADHD, particularly in adults, is largely unknown. ...

    • Expanding the activity spectrum of antiviral agents 

      Ianevski, Aleksandr; Andersen, Petter I.; Merits, Andres; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2019)

    • Expanding the coverage of regulons from high-confidence prior knowledge for accurate estimation of transcription factor activities 

      Müller-Dott, Sophia; Tsirvouli, Eirini; Vazquez, Miguel; Ramirez Flores, Ricardo O; Badia-I-Mompel, Pau; Fallegger, Robin; Türei, Dénes; Lægreid, Astrid Renner; Saez-Rodriguez, Julio (Peer reviewed; Journal article, 2023)
      Gene regulation plays a critical role in the cellular processes that underlie human health and disease. The regulatory relationship between transcription factors (TFs), key regulators of gene expression, and their target ...

    • Expanding the utilization of formalin-fixed, paraffin-embedded archives: Feasibility of miR-Seq for disease exploration and biomarker development from biopsies with clear cell renal cell Carcinoma 

      Strauss, Philipp; Marti, Hans-Peter; Beisland, Christian; Scherer, Andreas; Lysne, Vegard; Leh, Sabine Maria; Flatberg, Arnar; Koch, Even Evjen; Beisvag, Vidar; Landolt, Lea Zoe; Skogstrand, Trude; Eikrem, Øystein Solberg (Journal article; Peer reviewed, 2018)
      Novel predictive tools for clear cell renal cell carcinoma (ccRCC) are urgently needed. MicroRNAs (miRNAs) have been increasingly investigated for their predictive value, and formalin-fixed paraffin-embedded biopsy archives ...

    • Experiences among school personnel and school nurses on educational adaptations for students with CFS/ME: A qualitative interview study 

      Similä, Wenche Ann; Rø, Torstein Baade; Nøst, Torunn Hatlen (Peer reviewed; Journal article, 2021)
      Introduction: Chronic fatigue syndrome (CFS/ME) is a disabling disease severely impacting school attendance, education, and social life in young students. Uncertainties surrounding CFS/ME etiology may impact the interpretation ...

    • Experiences and perceptions of foreign-language customers on medication information received in the pharmacy – a focus group study 

      Sletvold, Hege; Nguyen, Thianna (Peer reviewed; Journal article, 2021)
      Background In pharmacies, communication is essential for providing information about medicine and counselling customers on the correct use of medications. Previous studies have described pharmacists experiencing language ...

    • Experiences of childbirth care among immigrant and non-immigrant women: a cross-sectional questionnaire study from a hospital in Norway 

      Reppen, Kristin; Henriksen, Lena; Schei, Berit; Magnussen, Elisabeth Balstad; Infanti, Jennifer Jean (Peer reviewed; Journal article, 2023)
      Background Immigrant women have higher risks for poor pregnancy outcomes and unsatisfactory birth experiences than the general population. The mechanisms behind these associations remain largely unknown, but they may ...

    • Experimental-Computational Approaches to Identify Synergistic Effects of Anti-Cancer Drugs 

      Niederdorfer, Barbara (Doctoral theses at NTNU;2019:384, Doctoral thesis, 2019)
      Drug combinations are hoped to improve treatment response to anti-cancer drugs by targeting the cancers vulnerabilities at diverse trajectories. With a large number of approved agents of chemotherapeutic and targeted ...