Browsing Institutt for klinisk og molekylær medisin by Title
Now showing items 1343-1362 of 3426
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H2G-Net: A multi-resolution refinement approach for segmentation of breast cancer region in gigapixel histopathological images
(Journal article; Peer reviewed, 2022)Over the past decades, histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation ... -
H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model
(Peer reviewed; Journal article, 2023)Kidney extraction time has a detrimental effect on post-transplantation outcome. This study aims to improve the flush-out and potentially decrease ischemic injury by the addition of hydrogen sulphide (H2S) to the flush ... -
Halogenated Pyrrolopyrimidines with Low MIC on Staphylococcus aureus and Synergistic Effects with an Antimicrobial Peptide
(Peer reviewed; Journal article, 2022)Currently, there is a world-wide rise in antibiotic resistance causing burdens to individuals and public healthcare systems. At the same time drug development is lagging behind. Therefore, finding new ways of treating ... -
Haplotype Analysis of Suspected Lynch Syndrome Families
(Master thesis, 2019)Lynch syndrome is the most common type of hereditary colorectal cancer and is characterized by a germline mutation in one of the DNA mismatch repair (MMR) genes (PMS2, MSH2, MSH6 or MLH1). Identification of Lynch syndrome ... -
Håndtering av legemiddelmangel i apotek - En kvalitativ studie med fokus på apotekkunders perspektiv
(Master thesis, 2021)Bakgrunn Det eksisterer per i dag ikke en uniform definisjon for legemiddelmangel, noe som gjør analyse av årsaker, omfang og kommunikasjon om problemet vanskelig. Omfanget synes å øke for hvert år, og 1 av 3 apotekkunder ... -
Håndtering av legemiddelmangel i apotek: En kvalitativ studie fra farmasøyters perspektiv
(Master thesis, 2021)Sammendrag Bakgrunn Antall tilfeller av legemiddelmangel er økende både i Norge og globalt. Apotekforeningens spørreundersøkelse fra 2019 viser at 1 av 3 legemiddelbrukere er bekymret for legemiddelmangel. Farmasøytens ... -
HbA1c as screening for gestational diabetes mellitus in women with polycystic ovary syndrome
(Journal article; Peer reviewed, 2015)Background Gestational diabetes mellitus (GDM) is associated with adverse pregnancy outcomes such as preeclampsia and macrosomia. Women with polycystic ovary syndrome (PCOS) are at increased risk of developing GDM. ... -
HDACi Mediate UNG2 Depletion, Dysregulated Genomic Uracil and Altered Expression of Oncoproteins and Tumor Suppressors in B- And T-cell Lines
(Peer reviewed; Journal article, 2020)Background HDAC inhibitors (HDACi) belong to a new group of chemotherapeutics that are increasingly used in the treatment of lymphocyte-derived malignancies, but their mechanisms of action remain poorly understood. Here ... -
Health care providers underestimate symptom intensities of cancer patients: A multicenter European study
(Journal article; Peer reviewed, 2010)Background: Many patients with advanced cancer depend upon health care providers for symptom assessment. The extent of agreement between patient and provider symptom assessments and the association of agreement with ... -
Health-related quality of life after camp-based family obesity treatment: an RCT
(Journal article; Peer reviewed, 2019)Objective To compare the effects of a 2-year camp-based immersion family treatment for obesity with an outpatient family-based treatment for obesity on health-related quality of life (HRQoL) in two generations. Design ... -
Health-Related Quality of Life after Radiotherapy: Epistemological, methodological and clinical issues
(Doktoravhandlinger ved NTNU, 1503-8181; 2013:110, Doctoral thesis, 2013)Background: Advances in the diagnosis and treatment of cancer have led to increasing survival rates, and fortunately, more cancer patients are becoming cancer survivors. The other side of the coin is that more people are ... -
Health-related quality of life and psychological distress in young adult survivors of childhood cancer and their association with treatment, education, and demographic factors
(Journal article; Peer reviewed, 2017)Purpose This study investigated health-related quality of life (HRQOL) and psychological distress among young adult (YA) survivors of childhood cancer and the association of these measures with treatment, education, and ... -
Health-related quality of life and sleep quality after 12 months of treatment in non-severe obstructive sleep apnea: A randomized clinical trial with Continuous Positive Airway Pressure and Mandibular Advancement Splints
(Peer reviewed; Journal article, 2020)In this randomized controlled trial, patients with non-severe obstructive sleep apnea (OSA) were treated with continuous positive airway pressure (CPAP) or a twin block mandibular advancement splint (MAS). The primary ... -
Health-related quality of life from 20 to 32 years of age in very low birth weight individuals: a longitudinal study
(Peer reviewed; Journal article, 2022)Background Preterm birth with very low birth weight (VLBW, birth weight < 1500 g) is associated with health problems later in life. How VLBW individuals perceive their physical and mental health-related quality of life ... -
Health-related quality of life in Norwegian adolescent living with chronic fatigue syndrome
(Peer reviewed; Journal article, 2020)Purpose The primary aim was to measure health related quality of life (HRQoL) in a Norwegian cohort of adolescents with Chronic Fatigue Syndrome (CFS/ME). A secondary aim was to identify factors before diagnosis, at time ... -
Health-related quality of life in transplant ineligible newly diagnosed multiple myeloma patients treated with either thalidomide or lenalidomide-based regimen until progression: a prospective, open-label, multicenter, randomized, phase 3 study
(Peer reviewed; Journal article, 2019)Data on the impact of long term treatment with immunomodulatory drugs (IMiD) on health-related quality of life (HRQoL) is limited. The HOVON-87/NMSG18 study was a randomized, phase 3 study in newly diagnosed transplant ... -
Health-related quality of life in young adults born small for gestational age: a prospective cohort study
(Peer reviewed; Journal article, 2022)Background Individuals born small for gestational age (SGA) have an increased risk of several adverse health outcomes, but their health-related quality of life (HRQoL) across young adulthood has yet to be studied. The ... -
Health-related quality of life in Young People with Chronic fatigue syndrome/ Myalgic encephalomyelitis
(Doctoral theses at NTNU;2022:113, Doctoral thesis, 2022)Summary Background Chronic fatigue syndrome/Myalgic encephalomyelitis (CFS/ME) is a disease that affects people of all ages. CFS/ME significantly limits the activity level of those affected, including in relation to ... -
Health-Related Quality-of-Life Outcomes of Very Preterm or Very Low Birth Weight Adults: Evidence From an Individual Participant Data Meta-Analysis
(Peer reviewed; Journal article, 2022)Background and Objective Assessment of health-related quality of life for individuals born very preterm and/or low birthweight (VP/VLBW) offers valuable complementary information alongside biomedical assessments. However, ... -
Healthcare professionals’ support to primary family carers of patients with advanced cancer
(Doctoral theses at NTNU;2022:317, Doctoral thesis, 2022)