Browsing Fakultet for medisin og helsevitenskap (MH) by Author "Uglem, Martin"
Now showing items 1-18 of 18
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Accuracy of neuropathic pain measurements in patients with symptoms of polyneuropathy: validation of painDETECT, Self-Completed Leeds Assessment of Neuropathic Symptoms and Signs, and Douleur Neuropathique 4
Dunker, Øystein; Grotle, Margreth; Kvaløy, Marie Bu; Uglem, Martin; Løseth, Sissel; Hjelland, Ina Elen; Kleggetveit, Inge Petter; Allen, Sara Maria; Vigeland, Maria Dehli; Killingmo, Rikke Munk; Sand, Trond; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2022)Pain is a common symptom in patients referred to polyneuropathy assessment. Diagnostic evaluation and choice of treatment may depend on whether the pain is likely to be neuropathic or not. This study aimed to investigate ... -
Diagnostic accuracy of the 5.07 monofilament test for diabetes polyneuropathy: influence of age, sex, neuropathic pain and neuropathy severity
Dunker, Øystein; Uglem, Martin; Kvaløy, Marie Bu; Løseth, Sissel; Hjelland, Ina Elen; Allen, Sara Maria; Vigeland, Maria Dehli; Kleggetveit, Inge Petter; Sand, Trond Halfdan; Nilsen, Kristian Bernhard (Peer reviewed; Journal article, 2023)Introduction There is a need for simple and cheap diagnostic tools for diabetic polyneuropathy (DPN). We aimed to assess the diagnostic accuracy of the 5.07/10 g monofilament test in patients referred to polyneuropathy ... -
Does pain sensitivity change by migraine phase? A blinded longitudinal study
Hagen, Knut; Omland, Petter Moe; Stovner, Lars Jacob; Sand, Trond Halfdan; Uglem, Martin; Tronvik, Erling Andreas; Nilsen, Kristian Bernhard; Linde, Anders Mattias (Journal article; Peer reviewed, 2016)Objective: Studies suggest that pain thresholds may be altered before and during migraine headaches, but it is still debated if a central or peripheral dysfunction is responsible for the onset of pain in migraine. The ... -
Effects of insufficient sleep on sensorimotor processing in migraine. A randomised, blinded crossover study of event related beta oscillations
Mykland, Martin Syvertsen; Uglem, Martin; Bjørk, Marte-Helene; Matre, Dagfinn; Sand, Trond Halfdan; Omland, Petter Moe (Peer reviewed; Journal article, 2023)Background Migraine has a largely unexplained connection with sleep and is possibly related to a dysfunction of thalamocortical systems and cortical inhibition. In this study we investigate the effect of insufficient sleep ... -
Experimental pain after sleep restriction and cortical excitability in migraine patients: From cross-sectional studies in the interictal phase to crossover studies on the effect of sleep restriction
Neverdahl, Jan Petter (Doctoral theses at NTNU;2024:10, Doctoral thesis, 2024)Migraine is a common and debilitating primary headache disorder. Despite having pronounced personal, societal, and economical costs, the pathophysiology of migraine is not fully elucidated. Migraine patients experience ... -
Experimental pain and migraine: Investigating the effect of non-invasive cortical modulation of pain, and phasic alterations of pain in migraineurs
Uglem, Martin (Doctoral theses at NTNU;2018:130, Doctoral thesis, 2018)Background: Both clinical symptoms, imaging findings, and neurophysiological measures suggest varying cyclic alterations in CNS-function between, before, during and after the migraine headache. Altered pain perception ... -
Fluctuations of sensorimotor processing in migraine: A controlled longitudinal study of beta event related desynchronization
Mykland, Martin Syvertsen; Bjørk, Marte-Helene; Stjern, Marit; Omland, Petter Moe; Uglem, Martin; Sand, Trond (Journal article; Peer reviewed, 2019)Background The migraine brain seems to undergo cyclic fluctuations of sensory processing. For instance, during the preictal phase, migraineurs experience symptoms and signs of altered pain perception as well as other ... -
Habituation of laser-evoked potentials by migraine phase: a blinded longitudinal study.
Uglem, Martin; Omland, Petter Moe; Stjern, Marit; Gravdahl, Gøril Bruvik; Sand, Trond (Journal article; Peer reviewed, 2017)Background Migraineurs seem to have cyclic variations in cortical excitability in several neurophysiological modalities. Laser-evoked potentials (LEP) are of particular interest in migraine because LEP specifically targets ... -
Insufficient sleep may alter cortical excitability near the migraine attack: A blinded TMS crossover study
Mykland, Martin Syvertsen; Uglem, Martin; Stovner, Lars Jacob; Brenner, Eiliv; Snoen, Mari Storli; Gravdahl, Gøril Bruvik; Sand, Trond Halfdan; Omland, Petter Moe (Peer reviewed; Journal article, 2023)Background Migraine is a brain disorder with a multifaceted and unexplained association to sleep. Brain excitability likely changes periodically throughout the migraine cycle. In this study we examine the effect of ... -
Migraine and sleep: The effects of insufficient sleep on brain function in migraine
Mykland, Martin Syvertsen (Doctoral theses at NTNU;2023:330, Doctoral thesis, 2023)Background Migraine affects about 15 % of the adult population aged 15-64 years old. The combined large prevalence and considerable disability of migraine makes it the first cause of most years lived with disability below ... -
Neuropathy 10-15 years after Roux-en-Y gastric bypass for severe obesity: A controlled cross-sectional nerve conduction study
Sand, Trond; Grøtting, Arnstein; Uglem, Martin; Augestad, Nils; Sandvik, Jorunn (Master thesis, 2022)Vårt mål var å lete etter langtidskomplikasjoner i det perifere nervesystemet 10-15 år etter bariatrisk kirurgi med Roux-en-Y gastrisk bypass. Vi rekrutterte 175 pasienter med alder 52.0 (9.2), BMI gjennomsnitt=35.2 og en ... -
Non-invasive cortical modulation of experimental pain in migraine
Uglem, Martin; Omland, Petter Moe; Engstrøm, Morten; Gravdahl, Gøril Bruvik; Linde, Mattias; Hagen, Knut; Sand, Trond (Journal article; Peer reviewed, 2016)Objective: To test the hypothesis that secondary somatosensory cortex (S2) is involved in the migraine pathogenesis, by exploring the effect of navigated repetitive transcranial magnetic stimulation (rTMS) to S2 on ... -
Pain sensitivity and thermal detection thresholds in young adults born preterm with very low birth weight or small for gestational age at term compared with controls
Iversen, Johanne Marie; Uglem, Martin; Indredavik, Marit Sæbø; Romundstad, Pål Richard; Nilsen, Kristian Bernhard; Sand, Trond; Rygg, Marite (Journal article; Peer reviewed, 2018)The objective of this prospective long-term follow-up study was to investigate whether somatosensory function is altered among young adults born preterm with very low birth weight (VLBW; ≤1,500 g) or small for gestational ... -
Pain sensitivity in young adults with juvenile idiopathic arthritis: a quantitative sensory testing study
Arnstad, Ellen Dalen; Iversen, Johanne Marie; Uglem, Martin; Glerup, Mia; Romundstad, Pål Richard; Sand, Trond; Rygg, Marite (Peer reviewed; Journal article, 2020)Background: To study for the first-time, pain perception, pain sensitivity, and self-reported pain in young adults with long disease duration of juvenile idiopathic arthritis (JIA) compared with controls. Methods: Children ... -
Referansegrenser for ultralydundersøkelse av perifere nerver
Eraker, Idun Matilde; Myrhaug, Astrid (Master thesis, 2024)Hensikten med denne studien var å undersøke om det ville være gunstig å utvikle egne referansegrenser for ultralydmålinger av tverrsnittareal i n. medianus, n. ulnaris og n. vagus for St. Olavs Hospital. Dette ble gjort ... -
Referansegrenser for ultralydundersøkelse av perifere nerver
Eraker, Idun Mathilde; Myrhaug, Astrid (Master thesis, 2024)Hensikten med denne studien var å undersøke om det ville være gunstig å utvikle egne referansegrenser for ultralydmålinger av tverrsnittareal i n. medianus, n. ulnaris og n. vagus for St. Olavs Hospital. Dette ble gjort ... -
Sleep restriction alters cortical inhibition in migraine: A transcranial magnetic stimulation study
Mykland, Martin Syvertsen; Uglem, Martin; Neverdahl, Jan Petter; Øie, Lise Rystad; Meisingset, Tore Wergeland; Dodick, David W.; Tronvik, Erling Andreas; Engstrøm, Morten; Sand, Trond; Omland, Petter Moe (Peer reviewed; Journal article, 2022)Objective Migraine is a primary headache disorder with a well-known association with insufficient sleep. However, both the underlying pathophysiology of the disease and the relationship with sleep is still unexplained. In ... -
Visual evoked potentials in migraine: Is the "neurophysiological hallmark" concept still valid?
Hagen, Knut; Sand, Trond; Uglem, Martin; Tronvik, Erling Andreas; Linde, Mattias; Omland, Petter Moe (Journal article; Peer reviewed, 2016)Objective: Lack of habituation is considered a neurophysiological hallmark of migraine. However, the results of visual evoked potential (VEP) studies have been discrepant, possibly because of different stimulation parameters ...