Blar i Institutt for teknisk kybernetikk på emneord "VDP::Medical technology: 620"

Viser treff 1-20 av 23

    • The Artificial Pancreas: Two Alternative Approaches to Achieve a Fully Closed Loop System with Optimal Glucose Control 

      Åm, Marte Kierulf; Teigen, Ingrid Anna; Riaz, Misbah; Fougner, Anders Lyngvi; Christiansen, Sverre Christian; Carlsen, Sven Magnus (Peer reviewed; Journal article, 2023)
      Introduction Diabetes mellitus type 1 is a chronic disease that implies mandatory external insulin delivery. The patients must monitor their blood glucose levels and administer appropriate insulin boluses to keep their ...

    • Blood Glucose Level Prediction Using Subcutaneous Sensors for in Vivo Study: Compensation for Measurement Method Slow Dynamics Using a Kalman Filter Approach 

      Halvorsen, Martha; Davari Benam, Karim; Khoshamadi, Hasti; Fougner, Anders Lyngvi (Chapter, 2022)
      The continuous glucose monitoring (CGM) system is the most common system used by people with type 1 diabetes to monitor blood glucose levels. However, it measures glucose in interstitial fluid in subcutaneous tissue rather ...

    • Data Driven Filtering of Bowel Sounds Using Multivariate Empirical Mode Decomposition 

      Kölle, Konstanze; Aftab, Muhammad Faisal; Andersson, Leif Erik; Fougner, Anders Lyngvi; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Background The analysis of abdominal sounds can help to diagnose gastro-intestinal diseases. Sounds originating from the stomach and the intestine, the so-called bowel sounds, occur in various forms. They are described ...

    • Data-Driven Classifiers for Early Meal Detection Using ECG 

      Cheema, Muhammad Asaad; Patil, Pallavi; Siddiqui, Salman Ijaz; Salvo Rossi, Pierluigi; Stavdahl, Øyvind; Fougner, Anders Lyngvi (Peer reviewed; Journal article, 2023)
      This study investigates the potential of the electrocardiogram (ECG) to perform early meal detection, which is critical for developing a fully-functional automatic artificial pancreas. The study was conducted in a group ...

    • Design of a compact, reconfigurable, prosthetic wrist 

      Zinck, Arthur; Stavdahl, Øyvind; Biden, Edmund; Kyberd, Peter Joseph (Journal article; Peer reviewed, 2012)
      The design of a prosthetic wrist is the result of compromises between the function and the practicality of the device. Conventional prosthetic wrists use a single degree of freedom to produce pro/supination of the hand. ...

    • Differences Between Flash Glucose Monitor and Fingerprick Measurements 

      Staal, Odd Martin; Hansen, Heidi Marie Umbach; Christiansen, Sverre; Fougner, Anders Lyngvi; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2018)
      Freestyle Libre (FL) is a factory calibrated Flash Glucose Monitor (FGM). We investigated Mean Absolute Relative Difference (MARD) between Self Monitoring of Blood Glucose (SMBG) and FL measurements in the first day of ...

    • Estimation and Prediction of Glucose Appearance Rate for Use in a Fully Closed-Loop Dual-Hormone Intraperitoneal Artificial Pancreas 

      Davari Benam, Karim; Gros, Sebastien Nicolas; Fougner, Anders Lyngvi (Peer reviewed; Journal article, 2023)
      Objective: A fully automated artificial pancreas requires a meal estimator and predictions of blood glucose levels (BGL) to handle disturbances during meal times, all without relying on manual meal announcements and user ...

    • Feasibility of early meal detection based on abdominal sound. 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Ellingsen, Reinold; Carlsen, Sven Magnus; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Background In classical approaches for an artificial pancreas, continuous glucose monitoring (CGM) is the only measured variable used for insulin dosing and additional control functions. The CGM values are subject to time ...

    • Fully Automated Bi-Hormonal Intraperitoneal Artificial Pancreas Using a Two-Layer PID Control Scheme 

      Langholz, Jana; Davari Benam, Karim; Sharan, Bindu; Gros, Sebastien Nicolas; Fougner, Anders Lyngvi (Chapter, 2023)
      Treatment of type 1 diabetes mellitus is significantly improved by using commercially available hybrid closed-loop systems to deliver insulin. These systems, also called artificial pancreas (AP), use the subcutaneous (SC) ...

    • Glucose-insulin metabolism model reduction and parameter selection using sensitivity analysis 

      Staal, Odd Martin; Fougner, Anders Lyngvi; Sælid, Steinar; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Glucose-insulin metabolism models are useful tools for research on diabetes, in development of diabetes-related medical devices like artificial pancreas systems, insulin pumps and continuous glucose monitors, and may also ...

    • Identifiable Prediction Animal Model for the Bi-Hormonal Intraperitoneal Artificial Pancreas 

      Davari Benam, Karim; Khoshamadi, Hasti; Åm, Marte Kierulf; Stavdahl, Øyvind; Gros, Sebastien; Fougner, Anders Lyngvi (Peer reviewed; Journal article, 2022)
      To achieve a fully automatic artificial pancreas (AP), i.e., an AP without the need for meal announcements, the intraperitoneal (IP) route is explored. This route has faster dynamics than the typical subcutaneous (SC) ...

    • Low-Order Nonlinear Animal Model of Glucose Dynamics for a Bihormonal Intraperitoneal Artificial Pancreas 

      Lopez Zazueta, Claudia; Stavdahl, Øyvind; Fougner, Anders Lyngvi (Peer reviewed; Journal article, 2021)
      Objective: The design of an Artificial Pancreas to regulate blood glucose levels requires reliable control methods. Model Predictive Control has emerged as a promising approach for glycemia control. However, model-based ...

    • Meal estimation from Continuous Glucose Monitor data using Kalman filtering and hypothesis testing 

      Staal, Odd Martin; Sælid, Steinar; Fougner, Anders Lyngvi; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      A method for estimating meal inputs from Continuous Glucose Monitoring (CGM) data is presented. The method is based on Kalman filtering and hypothesis testing, and provides estimates of the time the meal was initiated and ...

    • Mobile Software Development Kit for Real Time Multivariate Blood Glucose Prediction 

      Wolff, Miriam Kopperstad; Schaathun, Hans Georg; Fougner, Anders Lyngvi; Steinert, Martin; Volden, Rune (Journal article; Peer reviewed, 2024)
      In the field of blood glucose prediction, the literature is abounded with algorithms that demonstrate potential in glucose management. However, these propositions face an issue common to many machine learning algorithms: ...

    • Modelling and simulation of occlusions in insulin pumps 

      Formo, Mads Wikmark; Stavdahl, Øyvind; Fougner, Anders Lyngvi (Chapter, 2021)
      Abstract — An open source simulation model of the mechanical properties of a fully functional insulin pump was made in Matlab Simscape. The model simulates realistic behavior of an insulin pump, parts of which are validated ...

    • A Nonlinear State Observer for the Bi-Hormonal Intraperitoneal Artificial Pancreas 

      Davari Benam, Karim; Khoshamadi, Hasti; Lema-Pérez, Laura; Gros, Sebastien; Fougner, Anders Lyngvi (Chapter, 2022)
      Currently, continuous glucose monitoring sensors are used in the artificial pancreas to monitor blood glucose levels. However, insulin and glucagon concentrations in different parts of the body cannot be measured in ...

    • Optimal Experimental Design to Estimate Insulin Response in Type 2 Diabetes 

      Engell, Sarah Ellinor; Bengtsson, Henrik; Davari Benam, Karim; Fougner, Anders Lyngvi; Jørgensen, John Bagterp (Chapter, 2023)
      In late-stage type 2 diabetes, automated titration algorithms provide a promising alternative to the current standard-of-care. Many published methods rely on personalized dose-response models to predict a safe and effective ...

    • Pattern recognition reveals characteristic postprandial glucose changes: Non-individualized meal detection in diabetes mellitus type 1 

      Kölle, Konstanze; Biester, Torben; Christiansen, Sverre; Fougner, Anders Lyngvi; Stavdahl, Øyvind (Journal article; Peer reviewed, 2019)
      Accurate continuous glucose monitoring (CGM) is essential for fully automated glucose control in diabetes mellitus type 1. State-of-the-art glucose control systems automatically regulate the basal insulin infusion. Users ...

    • Pilot study of Early Meal Onset Detection from Abdominal Sounds 

      Setti, Sunilkumar Telagam; Søiland, Elise; Stavdahl, Øyvind; Fougner, Anders Lyngvi (Chapter, 2019)
      A typical artificial pancreas depends only on the continuous glucose monitoring (CGM) value for insulin dosing. However, both the insulin infusion and the glucose sensing are subject to time delays and slow dynamics. An ...

    • Risk Analysis for the Design of a Safe Artificial Pancreas Control System 

      Kölle, Konstanze; Fougner, Anders Lyngvi; Lundteigen, Mary Ann; Carlsen, Sven Magnus; Ellingsen, Reinold; Stavdahl, Øyvind (Journal article; Peer reviewed, 2018)
      Closed-loop glucose control has the potential to improve the glycemic control in patients with diabetes mellitus type 1. Such an artificial pancreas (AP) should keep the user safe despite all disturbances and faults. The ...