Blar i Fakultet for informasjonsteknologi og elektroteknikk (IE) på tidsskrift "Nucleic Acids Research"
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A manually curated ChIP-seq benchmark demonstrates room for improvement in current peak-finder programs
(Journal article; Peer reviewed, 2011)Chromatin immunoprecipitation (ChIP) followed by high throughput sequencing (ChIP-seq) is rapidly becoming the method of choice for discovering cell-specific transcription factor binding locations genome wide. By aligning ... -
Inferring causative variants in microRNA target sites
(Journal article; Peer reviewed, 2011)MicroRNAs (miRNAs) regulate genes post transcription by pairing with messenger RNA (mRNA). Variants such as single nucleotide polymorphisms (SNPs) in miRNA regulatory regions might result in altered protein levels and ... -
Loss of Mediator complex subunit 13 (MED13) promotes resistance to alkylation through cyclin D1 upregulation
(Peer reviewed; Journal article, 2020)Alkylating drugs are among the most often used chemotherapeutics. While cancer cells frequently develop resistance to alkylation treatments, detailed understanding of mechanisms that lead to the resistance is limited. Here, ... -
Transcription profiling during the cell cycle shows that a subset of Polycomb-targeted genes is upregulated during DNA replication
(Journal article; Peer reviewed, 2013)