Blar i Institutt for bioteknologi og matvitenskap på tidsskrift "BMC Systems Biology"
Viser treff 1-5 av 5
-
Fluxome study of Pseudomonas fluorescens reveals major reorganisation of carbon flux through central metabolic pathways in response to inactivation of the anti-sigma factor MucA
(Journal article; Peer reviewed, 2015)Background: The bacterium Pseudomonas fluorescens switches to an alginate-producing phenotype when the pleiotropic anti-sigma factor MucA is inactivated. The inactivation is accompanied by an increased biomass yield on ... -
Genome-level transcription data of Yersinia pestis analyzed with a New metabolic constraint-based approach
(Journal article; Peer reviewed, 2012)Background: Constraint-based computational approaches, such as flux balance analysis (FBA), have proven successful in modeling genome-level metabolic behavior for conditions where a set of simple cellular objectives can ... -
Hypothetical biomolecular probe based on a genetic switch with tunable symmetry and stability
(Peer reviewed; Journal article, 2016)Background Genetic switches are ubiquitous in nature, frequently associated with the control of cellular functions and developmental programs. In the realm of synthetic biology, it is of great interest to engineer genetic ... -
Mapping global effects of the anti-sigma factor MucA in Pseudomonas fluorescens SBW25 through genome-scale metabolic modeling
(Journal article; Peer reviewed, 2013)Background: Alginate is an industrially important polysaccharide, currently produced commercially by harvesting of marine brown sea-weeds. The polymer is also synthesized as an exo-polysaccharide by bacteria belonging to ... -
Optimized submerged batch fermentation strategy for systems scale studies of metabolic switching in Streptomyces coelicolor A3(2)
(Journal article; Peer reviewed, 2012)Background: Systems biology approaches to study metabolic switching in Streptomyces coelicolor A3(2) depend on cultivation conditions ensuring high reproducibility and distinct phases of culture growth and secondary ...