• In silico analysis provides insights for patient-specific annuloplasty in Barlow's disease 

      Aguilera, Hans Martin Dahl; Persson, Robert; Haaverstad, Rune; Skallerud, Bjørn Helge; Prot, Victorien Emile; Urheim, Stig (Peer reviewed; Journal article, 2023)
      Objective To predict the required mitral annular area reduction in patients with Barlow's disease to obtain a predefined leaflet area index by a novel in silico modeling method. Methods Three-dimensional echocardiography ...
    • Mechanical behavior and collagen structure of degenerative mitral valve leaflets and a finite element model of primary mitral regurgitation 

      Sadeghinia, Mohammadjavad; Aguilera, Hans Martin Dahl; Urheim, Stig; Persson, Robert; Ellensen, Vegard Skalstad; Haaverstad, Rune; Holzapfel, Gerhard; Skallerud, Bjørn Helge; Prot, Victorien Emile (Peer reviewed; Journal article, 2023)
      Degenerative mitral valve disease is the main cause of primary mitral regurgitation with two phenotypes: fibroelastic deficiency (FED) often with localized myxomatous degeneration and diffuse myxomatous degeneration or ...
    • Mitral annular dynamics are influenced by left ventricular load and contractility in an acute animal model 

      Persson, Robert Matongo; Aguilera, Hans Martin Dahl; Kvitting, Jon Peder Escobar; Grong, Ketil; Prot, Victorien Emile; Salminen, Pirjo-Riitta; Svenheim, Bård; Leiknes, Anita; Stangeland, Lodve; Haaverstad, Rune; Urheim, Stig (Peer reviewed; Journal article, 2023)
      The purpose of this study was to investigate the effects of loading conditions and left ventricular (LV) contractility on mitral annular dynamics. In 10 anesthetized pigs, eight piezoelectric transducers were implanted ...
    • Numerical modeling of diseased mitral valves 

      Aguilera, Hans Martin Dahl (Doctoral theses at NTNU;2023:273, Doctoral thesis, 2023)
      In this thesis, we have developed methods to create digital replicas of patients’ mitral valves from echocardiographic images and perform structural simulations in a finite element framework. The methods allow us to study ...
    • Patient Specific Finite Element Modelling of a Barlow Mitral Valve 

      Aguilera, Hans Martin Dahl (Master thesis, 2019)
      Utviklingen av nøyaktige og pålitelige pasientspesifikke elementmetodemodeller av mitralklaffen, er et fundamentalt skritt for å forbedre og optimalisere pasientspesifikk behandling og diagnostisering. Videre kan nøyaktige ...