Vis enkel innførsel

dc.contributor.authorHildrum, Bjørn
dc.contributor.authorRomild, Ulla Kristina
dc.contributor.authorHolmen, Jostein
dc.date.accessioned2015-09-11T12:28:39Z
dc.date.accessioned2015-09-30T14:04:02Z
dc.date.available2015-09-11T12:28:39Z
dc.date.available2015-09-30T14:04:02Z
dc.date.issued2011
dc.identifier.citationBMC Public Health 2011, 11nb_NO
dc.identifier.issn1471-2458
dc.identifier.urihttp://hdl.handle.net/11250/1240903
dc.description.abstractBackground: For decades, symptoms of anxiety and depression have been included among psychological factors associated with development of hypertension. Although this has been questioned in recent studies, most findings have been based on a single assessment of mental distress at baseline. We examined these associations using repeated assessments of anxiety, depression and blood pressure. Methods: Data on 17,410 men and women aged 20 to 67 participating in the Nord-Trøndelag Health Study (HUNT) in Norway in 1984-86 were re-examined 11 and 22 years later. The main outcome was change in mean blood pressure (mm Hg) during follow-up. Results: We found that a high symptom level score (≥80th percentile) of combined anxiety and depression at baseline, as compared to a lower symptom level, was associated with lower mean systolic (-0.67 mm Hg, p = 0.044) and diastolic (-0.25 mm Hg, p = 0.201) blood pressure at year 22. A high symptom level present at all three examinations was associated with a stronger decrease in mean systolic (-1.59 mm Hg, p = 0.004) and diastolic (-0.78 mm Hg, p = 0.019) blood pressure and with a 20% (p = 0.001) lower risk of developing hypertension (BP ≥140/90 mm Hg) at year 22. The associations were only slightly attenuated in multivariate analyses, with no evidence of a mediating effect of alteration in heart rate. Conclusions: This study do not support previous hypothesis that emotional stress may be a cause of hypertension. Our findings indicate that symptoms of anxiety and depression are associated with decrease in blood pressure, particularly when a high symptom level can be detected over decades.nb_NO
dc.language.isoengnb_NO
dc.publisherBioMed Centralnb_NO
dc.titleAnxiety and depression lowers blood pressure: 22-year follow-up of the population based HUNT study, Norwaynb_NO
dc.typeJournal articlenb_NO
dc.typePeer revieweden_GB
dc.date.updated2015-09-11T12:28:39Z
dc.source.volume11nb_NO
dc.source.journalBMC Public Healthnb_NO
dc.identifier.doi10.1186/1471-2458-11-601
dc.identifier.cristin847356
dc.description.localcode© 2011 Hildrum et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.nb_NO


Tilhørende fil(er)

Thumbnail

Denne innførselen finnes i følgende samling(er)

Vis enkel innførsel