Browsing NTNU Open by Author "Zhang, Qindong"
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Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren
Castaneda Zegarra, Sergio Miguel; Huse, Camilla; Røsand, Øystein; Sarno, Antonio; Xing, Mengtan; Zhang, Qindong; Alirezaylavasani, Amin; Werner, Julia; Ji, Ping; Liabakk, Nina-Beate; Wang, Wei; Bjørås, Magnar; Oksenych, Valentyn (Journal article; Peer reviewed, 2019)Classical non-homologous end joining (NHEJ) is a molecular pathway that detects, processes, and ligates DNA double-strand breaks (DSBs) throughout the cell cycle. Mutations in several NHEJ genes result in neurological ... -
Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI
Castaneda Zegarra, Sergio Miguel; Zhang, Qindong; Alirezaylavasani, Amin; Fernandez-Berrocal, Marion Silvana; Yao, Rouan; Oksenych, Valentyn (Peer reviewed; Journal article, 2020)Non-homologous end-joining (NHEJ) is a DNA repair pathway required to detect, process, and ligate DNA double-stranded breaks (DSBs) throughout the cell cycle. The NHEJ pathway is necessary for V(D)J recombination in ...