• Prolonged cigarette smoke exposure alters mitochondrial structure and function in airway epithelial cells 

      Hoffmann, RF; Zarrintan, S; Brandenburg, SM; Kol, A; de Bruin, HG; Jafari, S; Dijk, F; Kalicharan, D; Kelders, M; Gosker, HR; ten Hacken, NHT; Van der Want, Johannes; van Oosterhout, AJM; Heijink, IH (Journal article; Peer reviewed, 2013)
      Background Cigarette smoking is the major risk factor for COPD, leading to chronic airway inflammation. We hypothesized that cigarette smoke induces structural and functional changes of airway epithelial mitochondria, ...