• Chronic fatigue syndromes: real illnesses that people can recover from 

      Alme, Tomas Nordheim; Andreasson, Anna; Asprusten, Tarjei Tørre; Bakken, Anne Karen; Beadsworth, Michael BJ; Boye, Birgitte; Brodal, Per; Brodwall, Elias Myrstad; Brurberg, Kjetil Gundro; Bugge, Ingrid; Chalder, Trudie; Due, Reidar; Eriksen, Hege Randi; Fink, Per Klausen; Flottorp, Signe Agnes; Fors, Egil Andreas; Jensen, Bård Fossli; Fundingsrud, Hans Petter; Garner, Paul; Havdal, Lise Beier; Helgeland, Helene; Jacobsen, Henrik Børsting; Johnson, Georg Espolin; Jonsjö, Martin; Knoop, Hans; Landmark, Live; Launes, Gunvor; Lekander, Mats; Linnros, Hannah; Lindsäter, Elin; Liira, Helena; Linnestad, Lina; Loge, Jon; Lyby, Peter Solvoll; Malik, Sadaf; Malt, Ulrik Fredrik; Moe, Trygve; Norlin, Anna-Karin; Pedersen, Maria; Pignatiello, Siv Elin; Rask, Charlotte Ulrikka; Reme, Silje Endresen; Roksund, Gisle; Sainio, Markku; Sharpe, Michael; Thorkildsen, Ruth Foseide; Van Roy, Betty; Vandvik, Per Olav; Vogt, Henrik; Wyller, Hedda Bratholm; Wyller, Vegard Bruun Bratholm (Peer reviewed; Journal article, 2023)
      The ‘Oslo Chronic Fatigue Consortium’ consists of researchers and clinicians who question the current narrative that chronic fatigue syndromes, including post-covid conditions, are incurable diseases. Instead, we propose ...
    • Clinical symptoms and markers of disease mechanisms in adolescent chronic fatigue following Epstein-Barr virus infection: An exploratory cross-sectional study 

      Kristiansen, Miriam Skjerven; Stabursvik, Julie; O'Leary, Elise Catriona; Pedersen, Maria; Asprusten, Tarjei Tørre; Leegaard, Truls Michael; Osnes, Liv T. N.; Tjade, Trygve Olav; Skovlund, Eva; Godang, Kristin; Wyller, Vegard Bruun Bratholm (Journal article; Peer reviewed, 2019)
      Introduction Acute Epstein-Barr virus (EBV) infection is a trigger of chronic fatigue (CF) and Chronic Fatigue Syndrome (CFS). The aim of this cross-sectional study was to explore clinical symptoms as well as markers of ...
    • Cognitive–behavioural therapy combined with music therapy for chronic fatigue following Epstein-Barr virus infection in adolescents: a randomised controlled trial 

      Malik, Sadaf; Asprusten, Tarjei Tørre; Pedersen, Maria; Mangersnes, Julie; Trondalen, Gro; Van Roy, Betty; Skovlund, Eva; Wyller, Vegard Bruun Bratholm (Peer reviewed; Journal article, 2020)
      Background Cognitive–behavioural therapy (CBT) is effective in chronic fatigue (CF) syndrome. However, CBT has not been investigated in postinfectious CF, nor is it known whether addition of therapeutic elements from other ...
    • EBV-requisitioning physicians' guess on fatigue state 6 months after acute EBV infection 

      Asprusten, Tarjei Tørre; Pedersen, Maria; Skovlund, Eva; Wyller, Vegard Bruun Bratholm (Journal article; Peer reviewed, 2019)
      We assessed referring medical practitioner’s ability to predict chronic fatigue development in adolescents presenting with acute infectious mononucleosis. Compared with ‘not fatigued’ being predicted as ‘unsurely fatigued’ ...
    • Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19 

      Sommen, Silke Lauren; Havdal, Lise Beier; Selvakumar, Joel Pradeepkumar; Einvik, Gunnar; Leegaard, Truls Michael; Lund-Johansen, Fridtjof; Michelsen, Annika Elisabet; Mollnes, Tom Eirik; Stiansen-Sonerud, Tonje; Tjade, Trygve Olav; Wyller, Vegard Bruun Bratholm; Lund-Berven, Lise (Peer reviewed; Journal article, 2022)
      Introduction: Both public and scientific attention have shifted from the acute COVID-19 illness to the chronic disability experienced by a proportion of COVID-19 convalescents. Post COVID-19 condition, a term used for ...
    • Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults 

      Berven, Lise; Selvakumar, Joel Pradeepkumar; Havdal, Lise Beier; Stiansen-Sonerud, Tonje; Einvik, Gunnar; Leegaard, Truls Michael; Tjade, Trygve Olav; Michelsen, Annika Elisabet; Mollnes, Tom Eirik; Wyller, Vegard Bruun Bratholm (Peer reviewed; Journal article, 2022)
      Summary: Mild, subacute COVID-19 in young people show inflammatory enhancement, but normal pulmonary function. Inflammatory markers are associated with age and male sex, whereas clinical symptoms are associated with age ...
    • Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue 

      Fevang, Børre; Wyller, Vegard Bruun Bratholm; Mollnes, Tom Eirik; Pedersen, Maria; Asprusten, Tarjei Tørre; Michelsen, Annika Elisabet; Ueland, Thor; Otterdal, Kari (Peer reviewed; Journal article, 2021)
      Background: Epstein-Barr virus (EBV) causes infectious mononucleosis (IM) that can lead to chronic fatigue syndrome. The CEBA-project (Chronic fatigue following acute EBV infection in Adolescents) has followed 200 patients ...
    • Predictors of chronic fatigue in adolescents six months after acute Epstein-Barr virus infection: a prospective cohort study 

      Pedersen, Maria; Asprusten, Tarjei Tørre; Godang, Kristin; Leegaard, Truls Michael; Osnes, Liv T. N.; Skovlund, Eva; Tjade, Trygve Olav; Øie, Merete Glenne; Wyller, Vegard Bruun Bratholm (Journal article; Peer reviewed, 2018)
      Introduction Acute Epstein-Barr virus (EBV) infection is a trigger of chronic fatigue and Chronic Fatigue Syndrome (CFS). This study investigated baseline predictors of chronic fatigue six months after an acute EBV ...
    • Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults 

      Selvakumar, Joel Pradeepkumar; Havdal, Lise Beier; Drevvatne, Martin Solstrand; Brodwall, Elias Myrstad; Lund-Berven, Lise; Stiansen-Sonerud, Tonje; Einvik, Gunnar; Leegaard, Truls Michael; Tjade, Trygve Olav; Michelsen, Annika Elisabet; Mollnes, Tom Eirik; Lund-Johansen, Fridtjof; Holmøy, Trygve; Zetterberg, Henrik; Blennow, Kaj; Sandler, Carolina X.; Cvejic, Erin; Lloyd, Andrew R.; Wyller, Vegard Bruun Bratholm (Peer reviewed; Journal article, 2023)
      Importance The prevalence and baseline risk factors of post–COVID-19 condition (PCC) remain unresolved among the large number of young people who experienced mild COVID-19. Objectives To determine the point prevalence ...
    • Systemix exertion intolerance disease diagnostic criteria Applied on an adolescent chronic fatigue syndrom cohort: evaluation of subgroup differences and prognostic utility 

      Asprusten, Tarjei Tørre; Sulheim, Dag; Fagermoen, Frode Even; Winger, Anette; Skovlund, Eva; Wyller, Vegard Bruun Bratholm (Journal article; Peer reviewed, 2018)
      Objective Existing case definitions for chronic fatigue syndrome (CFS) all have disputed validity. The present study investigates differences between adolescent patients with CFS who satisfy the systemic exertion intolerance ...
    • The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial 

      Hov, Karen Roksund; Neerland, Bjørn Erik; Undseth, Øystein; Wyller, Vegard Bruun Bratholm; MacLullich, Alasdair M.J.; Qvigstad, Eirik; Skovlund, Eva; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2019)
      Objectives The aim of this double‐blinded randomised placebo‐controlled trial was to investigate the efficacy of clonidine for delirium in medical inpatients greater than 65 years. Methods Acutely admitted medical ...
    • The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses 

      Hov, Karen Roksund; Neerland, Bjørn Erik; Andersen, Anders Mikal; Undseth, Øystein; Wyller, Vegard Bruun Bratholm; MacLullich, Alasdair M.J.; Skovlund, Eva; Qvigstad, Eirik; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2018)
      Background The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium. To assess the dosage regimen and safety measures ...