Browsing NTNU Open by Author "Wyller, Torgeir Bruun"
Now showing items 1-14 of 14
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Cooperation between geriatricians and general practitioners for improved pharmacotherapy in home-dwelling elderly people receiving polypharmacy - the COOP Study: Study protocol for a cluster randomised controlled trial
Romskaug, Rita; Molden, Espen; Straand, Jørund; Kersten, Hege; Skovlund, Eva; Pitkala, Kaisu H; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2017)Background Polypharmacy and inappropriate drug use is associated with negative health outcomes among older people. Various interventions for improving drug treatment have been evaluated, but the majority of studies are ... -
Delirium motor subtypes and prognosis in hospitalized geriatric patients – A prospective observational study
Evensen, Sigurd; Saltvedt, Ingvild; Lydersen, Stian; Wyller, Torgeir Bruun; Taraldsen, Kristin; Sletvold, Olav (Journal article; Peer reviewed, 2019)Objective Delirium is common and associated with poor outcomes. Hypoactive motor subtype may predict worse outcome than no-subtype, hyperactive and mixed delirium, but uncertainty remains due to heterogeneity of results ... -
DELIRIUM MOTOR SUBTYPES IN GERIATRIC PATIENTS: A prospective observational study on risk factors, motor activity and outcomes
Evensen, Sigurd (Doctoral theses at NTNU;2019:293, Doctoral thesis, 2019) -
Effect of clinical geriatric assessments and collaborative medication reviews by geriatrician and family physician for improving health-related quality of life in home-dwelling older patients receiving polypharmacy: a cluster randomized clinical trial
Romskaug, Rita; Skovlund, Eva; Straand, Jørund; Molden, Espen; Kersten, Hege; Pitkala, Kaisu H; Lundqvist, Christofer; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2019)Importance Polypharmacy and inappropriate drug regimens are major health concerns among older adults. Various interventions focused on medication optimization strategies have been carried out, but the effect on patient-relevant ... -
Environmental factors and risk of delirium in geriatric patients: An observational study
Evensen, Sigurd; Saltvedt, Ingvild; Lydersen, Stian; Wyller, Torgeir Bruun; Taraldsen, Kristin; Sletvold, Olav (Journal article; Peer reviewed, 2018)Background Patients with delirium have increased risk of death, dementia and institutionalization, and prognosis differs between delirium motor subtypes. A few studies have identified associations between environmental ... -
Frailty identified by geriatric assessment is associated with poor functioning, high symptom burden and increased risk of physical decline in older cancer patients: Prospective observational study
Kirkhus, Lene; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Rostoft, Siri; Harneshaug, Magnus; Selbæk, Geir; Wyller, Torgeir Bruun; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)Background: Maintaining quality of life including physical functioning is highly prioritized among older cancer patients. Geriatric assessment is a recommended approach to identify patients with increased vulnerability ... -
Geriatric assessment is superior to oncologists’ clinical judgement in identifying frailty
Kirkhus, Lene; Saltyte Benth, Jurate; Kristjansson, Siri Rostoft; Grønberg, Bjørn Henning; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Harneshaug, Magnus; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2017)Background: Frailty is a syndrome associated with increased vulnerability and an important predictor of outcomes in older cancer patients. Systematic assessments to identify frailty are seldom applied, and oncologists’ ... -
Modifiable factors affecting older patients' quality of life and physical function during cancer treatment
Kirkhus, Lene; Harneshaug, Magnus; Saltyte Benth, Jurate; Grønberg, Bjørn Henning; Rostoft, Siri; Bergh, Sverre; Hjermstad, Marianne Jensen; Selbæk, Geir; Wyller, Torgeir Bruun; Kirkevold, Øyvind; Borza, Tom; Saltvedt, Ingvild; Jordhøy, Marit Slaaen (Journal article; Peer reviewed, 2019)Background Maintaining physical function and quality of life (QoL) are prioritized outcomes among older adults. We aimed to identify potentially modifiable factors affecting older patients' physical function and QoL ... -
Motor activity across delirium motor subtypes in geriatric patients assessed using body-worn sensors: a Norwegian cross-sectional study
Evensen, Sigurd Storhaug; Bourke, Alan; Lydersen, Stian; Sletvold, Olav; Saltvedt, Ingvild; Wyller, Torgeir Bruun; Taraldsen, Kristin (Journal article; Peer reviewed, 2019)Objectives It remains unclear if geriatric patients with different delirium motor subtypes express different levels of motor activity. Thus, we used two accelerometer-based devices to simultaneously measure upright activity ... -
Post-discharge complications in frail older patients after surgery for colorectal cancer
Ommundsen, Nina; Nesbakken, Arild; Wyller, Torgeir Bruun; Skovlund, Eva; Bakka, Arne Olav; Jordhøy, Marit Slaaen; Rostoft, Siri (Journal article; Peer reviewed, 2018)Background The incidence of postoperative complications after colorectal cancer surgery varies between publications. Complications occurring after discharge from hospital are often not reported. The aims of this study ... -
The effect of a pre- and post-operative orthogeriatric service on cognitive function in patients with hip fracture. The protocol of the Oslo Orthogeriatrics Trial
Wyller, Torgeir Bruun; Watne, Leiv Otto; Torbergsen, Anne Cathrine; Engedal, Knut Arne; Frihagen, Frede Jon; Juliebø, Vibeke; Saltvedt, Ingvild; Skovlund, Eva; Ræder, Johan; Conroy, Simon (Journal article; Peer reviewed, 2012)Background Hip fractures mainly affect older people. It is associated with high morbidity and mortality, and in particular a high frequency of delirium. Incident delirium following hip fracture is associated with an ... -
The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: Randomized controlled trial (Oslo Orthogeriatric Trial)
Watne, Leiv Otto; Torbergsen, Anne Cathrine; Conroy, Simon; Engedal, Knut; Frihagen, Frede; Hjorthaug, Geir Aasmund; Juliebø, Vibeke; Ræder, Johan; Saltvedt, Ingvild; Skovlund, Eva; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2014)Background Delirium is a common complication in patients with hip fractures and is associated with an increased risk of subsequent dementia. The aim of this trial was to evaluate the effect of a pre- and postoperative ... -
The Oslo Study of Clonidine in Elderly Patients with Delirium; LUCID: a randomised placebo-controlled trial
Hov, Karen Roksund; Neerland, Bjørn Erik; Undseth, Øystein; Wyller, Vegard Bruun Bratholm; MacLullich, Alasdair M.J.; Qvigstad, Eirik; Skovlund, Eva; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2019)Objectives The aim of this double‐blinded randomised placebo‐controlled trial was to investigate the efficacy of clonidine for delirium in medical inpatients greater than 65 years. Methods Acutely admitted medical ... -
The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses
Hov, Karen Roksund; Neerland, Bjørn Erik; Andersen, Anders Mikal; Undseth, Øystein; Wyller, Vegard Bruun Bratholm; MacLullich, Alasdair M.J.; Skovlund, Eva; Qvigstad, Eirik; Wyller, Torgeir Bruun (Journal article; Peer reviewed, 2018)Background The Oslo Study of Clonidine in Elderly Patients with Delirium (LUCID) is an RCT investigating the effect of clonidine in medical patients > 65 years with delirium. To assess the dosage regimen and safety measures ...