Blar i NTNU Open på forfatter "Wrobel, Aleksandra Zofia"
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Exogenous miR-451a prevents MMP-9 upregulation in cardiac hypertrophy
Wrobel, Aleksandra Zofia (Master thesis, 2016)Matrix metalloproteinase-9 (MMP-9) degrades extracellular matrix and is increased in several cardiac pathologies. Recently microRNA (miR)-451a has been found to inhibit the expression of MMP-9 in human malignancies. However, ... -
microRNA-451a prevents activation of matrix metalloproteinases 2 and 9 in human cardiomyocytes during pathological stress stimulation.
Scrimgeour, Nathan Robert; Wrobel, Aleksandra Zofia; Pinho, Maria; Høydal, Morten (Peer reviewed; Journal article, 2019)Matrix metalloproteinases (MMP) are important for cardiac remodeling. Recently, microRNA (miR)-451a has been found to inhibit the expression of both MMP-2 and MMP-9 in human malignancies, but its role in cardiomyocytes has ...