• Complex I and its role in aerobic and anaerobic growth of Cereibacter sphaeroides 

      Fondevik, Eline (Bachelor thesis, 2022)
      Complex I is a big protein complex in the electron transport chain and works as the entry point of electrons from NADH into the electron transport chain. Complex I in Cereibacter sphaeroides differs from complex I in many ...
    • Determining the impact of the R249S mutation on Tp53 gene on cell survivability during AFB1 exposure 

      Fonnes, Helene (Bachelor thesis, 2022)
      Hepatocellular Carcinoma (HCC) is one of the most frequent and malignant cancers worldwide and is found to be endemic in the same geographically areas as high exposure with Aflatoxin B1 (AFB1). AFB1 is a mycotoxin, naturally ...
    • GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients 

      Neckmann, Ulrike; Wolowczyk, Camilla; Hall, Martina; Almaas, Eivind; Ren, Jiang; Zhao, Sen; Johannessen, Bjarne; Skotheim, Rolf I.; Bjørkøy, Geir; Dijke, Peter Ten; Holien, Toril (Journal article; Peer reviewed, 2019)
      Background In breast cancer, activation of bone morphogenetic protein (BMP) signaling and elevated levels of BMP-antagonists have been linked to tumor progression and metastasis. However, the simultaneous upregulation of ...
    • Heterogeneity within the 66cl4 cell line from the 4T1 model of metastatic breast cancer 

      Tran, Tuong Vy Thi (Master thesis, 2018)
      Breast cancer is one of the most common form of cancer among women globally and metastasis is the primary cause of death in breast cancer patients. In the past decades it has been increasingly known that tumors are ...
    • Tumor Targeting by αvβ3-Integrin-Specific Lipid Nanoparticles Occurs via Phagocyte Hitchhiking 

      Sofias, Alexandros Marios; Toner, Yohana C.; Meerwaldt, Anu E.; van Leent, Mandy M. T.; Soultanidis, Georgios; Elschot, Mattijs; Gonai, Haruki; Grendstad, Kristin; Flobak, Åsmund; Neckmann, Ulrike; Wolowczyk, Camilla; Fisher, Elizabeth L.; Reiner, Thomas; Davies, Catharina de Lange; Bjørkøy, Geir; Teunissen, Abraham J. P.; Ochando, Jordi; Pérez-Medina, Carlos; Mulder, Willem J. M.; Hak, Sjoerd (Journal article; Peer reviewed, 2020)
      Although the first nanomedicine was clinically approved more than two decades ago, nanoparticles’ (NP) in vivo behavior is complex and the immune system’s role in their application remains elusive. At present, only ...