• A small molecule activator of AKT does not reduce ischemic injury of the rat heart 

      Moreira, Jose Bianco Nascimento; Wohlwend, Martin; Alves, Marcia Netto Magalhaes; Wisløff, Ulrik; Bye, Anja (Journal article; Peer reviewed, 2015)
      Background Activation of protein kinase AKT is required for cardioprotection by ischemic preconditioning, and transgenic overexpression of AKT protects the heart against ischemia. However, it is unknown whether acute ...
    • Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial 

      Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)
      OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ...
    • Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity 

      Souza, Rodrigo W. A.; Alves, Christiano R. R.; Medeiros, Alessandra; Rolim, Natale Pinheiro Lage; Silva, Gustavo Jose Justo; Moreira, Jose Bianco Nascimento; Alves, Marcia Netto Magalhaes; Wohlwend, Martin; Gebriel, Mohammed; Hagen, Lars; Sharma, Animesh; Koch, Lauren G.; Britton, Steven L.; Slupphaug, Geir; Wisløff, Ulrik; Brum, Patricia C. (Journal article; Peer reviewed, 2018)
      Given the association between high aerobic capacity and the prevention of metabolic diseases, elucidating the mechanisms by which high aerobic capacity regulates whole-body metabolic homeostasis is a major research challenge. ...
    • Exercise and the Dark Human Genome reveal Gene-targets in Age-related Diseases 

      Wohlwend, Martin (Doctoral theses at NTNU, 2021:45, Doctoral thesis, 2021)
      Trening og det mørke genom avslører gen-targets i alders-relaterte sykdommer Konsekvensene av et aldrende samfunn er avhengig av en hovedfaktor: helse. Siden mennesker lever lenger og lenger mens helsen ikke følger denne ...
    • Investigation of an Exercise-Induced State of Hypofrontality: And its Potential Association with Central Fatigue 

      Wohlwend, Martin (Master thesis, 2012)
      The reticular-activating hypofrontality model of acute exercise (RAH) predicts exercise-induced hypoactivity in frontal cortex which mediates executive function. Connors Continuous Performance Test (CCPT) was used to ...