Browsing NTNU Open by Author "Westin, Andreas"
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Changes in drug disposition of lithium during pregnancy: A retrospective observational study of patient data from two routine therapeutic drug monitoring services in Norway
Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Aadal, Marianne; Spigset, Olav (Journal article; Peer reviewed, 2017)Objectives Pregnancy may cause changes in drug disposition, dose requirements and clinical response. For lithium, changes in disposition during pregnancy have so far been explored in a single-dose study on 4 participants ... -
Effects of age and gender on the serum levels of clozapine, olanzapine, risperidone, and quetiapine
Castberg, Ingrid Mehli; Westin, Andreas; Skogvoll, Eirik; Spigset, Olav (Journal article; Peer reviewed, 2017)Objective To investigate serum concentrations of second-generation antipsychotics in relation to age and gender in a population ranging from 18 to 100 years. Method Results from a routine therapeutic drug monitoring ... -
Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition
Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Spigset, Olav (Journal article; Peer reviewed, 2017)Background Pregnancy may cause changes in drug disposition. The clinical consequences may be profound and even counterintuitive; in some cases pregnant women may need more than twice their usual drug dose in order to ... -
Treatment with antipsychotics in pregnancy: changes in drug disposition
Westin, Andreas; Brekke, Malin; Molden, Espen; Skogvoll, Eirik; Castberg, Ingrid Mehli; Spigset, Olav (Journal article; Peer reviewed, 2017)Although pregnancy is known to cause changes in drug pharmacokinetics, little is known about its impact on serum levels of antipsychotics. In this study we retrospectively assessed 201 routine serum antipsychotic therapeutic ...