Browsing NTNU Open by Author "Wenger, Anna"

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Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells

Wenger, Anna; Werlenius, Katja; Hallner, Alexander; Fredrik Bergh, Thoren; Farahmand, Dan; Tisell, Magnus; Smits, Anja; Rydenhag, Bertil; Jakola, Asgeir Store; Caren, Helena (Peer reviewed; Journal article, 2018)

Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing the need for better treatments. Immunotherapy as a treatment for improving or aiding the patient’s ...
Intratumor DNA methylation heterogeneity in glioblastoma: Implications for DNA methylation-based classification

Wenger, Anna; Vega, Sandra Ferreyra; Kling, Teresia; Bontell, Thomas Olsson; Jakola, Asgeir S; Caren, Helena (Peer reviewed; Journal article, 2019)

Background. A feature of glioblastoma (GBM) is cellular and molecular heterogeneity, both within and between tumors. This variability causes a risk for sampling bias and potential tumor escape from future targeted therapy. ...