• Blood pressure and mortality: using offspring blood pressure as an instrument for own blood pressure in the HUNT study 

      Wade, Kaitlin H; Carslake, David; Nilsen, Tom Ivar Lund; Timpson, Nicholas J.; Davey Smith, George; Romundstad, Pål Richard (Peer reviewed; Journal article, 2015)
      Given that observational associations may be inaccurate, we used offspring blood pressure (BP) to provide alternative estimates of the associations between own BP and mortality. Observational associations between BP and ...
    • Common health conditions in childhood and adolescence, school absence, and educational attainment: Mendelian randomization study 

      Hughes, Amanda; Wade, Kaitlin H; Dickson, Matt; Rice, Frances; Davies, Alisha R.; Davies, Neil Martin; Howe, Laura D. (Peer reviewed; Journal article, 2021)
      Good health is positively related to children’s educational outcomes, but relationships may not be causal. Demonstrating a causal influence would strongly support childhood and adolescent health as important for education ...
    • Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis 

      Anderson, Emma L.; Richmond, Rebecca C.; Jones, Samuel E.; Hemani, Gibran; Wade, Kaitlin H; Dashti, Hassan S.; Lane, Jaqueline; Wang, Heming; Saxena, Richa; Brumpton, Ben Michael; Korologou-Linden, Roxanna; Nielsen, Jonas Bille; Åsvold, Bjørn Olav; Abecasis, Goncalo; Coulthard, Elizabeth; Kyle, Simon D.; Beaumont, Robin N.; Tyrell, Jessica; Frayling, Timothy M; Munafo, Marcus R; Wood, Andrew R; Ben-Shlomo, Yoav; Howe, Laura D; Lawlor, Deborah A.; Weedon, Michael N; Smith, George Davey (Peer reviewed; Journal article, 2020)
      Background It is established that Alzheimer’s disease (AD) patients experience sleep disruption. However, it remains unknown whether disruption in the quantity, quality or timing of sleep is a risk factor for the onset ...