Browsing NTNU Open by Author "Vanky, Eszter Ilona"
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Anthropometrics of neonates born to mothers with PCOS with metformin or placebo exposure in utero
Nilsen, Guro Ørndal; Simpson, Melanie Rae; Hanem, Liv Guro Engen; Løvvik, Tone Shetelig; Ødegård, Rønnaug Astri; Stokkeland, Live Marie T; Andersen, Marianne; Juliusson, Pétur Benedikt; Vanky, Eszter Ilona (Peer reviewed; Journal article, 2023)Introduction Fetal growth may be affected by both maternal polycystic ovary syndrome (PCOS) and metformin therapy. Here, we explore the effect of intrauterine metformin exposure on birth anthropometrics of infants born ... -
Growth Restriction in the Offspring of Mothers With Polycystic Ovary Syndrome
Talmo, Maren Sophie Aaserud; Fløysand, Ingvild Skogedal; Nilsen, Guro Ørndal; Løvvik, Tone Shetelig; Ødegård, Rønnaug Astri; Juliusson, Pétur Benedikt; Vanky, Eszter Ilona; Simpson, Melanie Rae (Peer reviewed; Journal article, 2024)Importance Polycystic ovary syndrome (PCOS) is a common endocrine disorder, characterized by subfertility, increased risk of metabolic diseases, and pregnancy complications. Previous studies diverge regarding the association ... -
Immunomodulatory Effects of Metformin Treatment in Pregnant Women With PCOS
Ryssdal, Mariell; Vanky, Eszter Ilona; Stokkeland, Live Marie T; Jarmund, Anders Hagen; Steinkjer, Bjørg; Løvvik, Tone Shetelig; Madssen, Torfinn Støve; Iversen, Ann-Charlotte; Giskeødegård, Guro F. (Journal article; Peer reviewed, 2023)Context: Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with low-grade systemic inflammation and increased risk of pregnancy complications. Metformin treatment reduces the risk of late miscarriage ... -
Maternal serum levels of prokineticin-1 related to pregnancy complications and metformin use in women with polycystic ovary syndrome: a post hoc analysis of two prospective, randomised, placebo-controlled trials
Ujvari, Dorina; Trouva, Anastasia; Hirschberg, Angelica Lindén; Vanky, Eszter Ilona (Peer reviewed; Journal article, 2023)Objective Serum prokineticin-1 (s-PROK1) in the second and third trimester of pregnancy is positively correlated to preeclampsia, intrauterine growth restriction (IUGR) and preterm delivery. Women with polycystic ovary ... -
Maternal thyroid function and offspring birth anthropometrics in women with polycystic ovary syndrome
Trouva, Anastasia; Alvarsson, Michael; Calissendorff, Jan; Åsvold, Bjørn Olav; Ujvari, Dorina; Hirschberg, Angelica Lindén; Vanky, Eszter Ilona (Journal article; Peer reviewed, 2024)Objectives: Polycystic ovary syndrome (PCOS) and thyroid disorders have both been linked to adverse pregnancy and neonatal outcomes. Even small variations in thyroid function within the normal range may influence fetal ... -
SPIOMET4HEALTH—efficacy, tolerability and safety of lifestyle intervention plus a fixed dose combination of spironolactone, pioglitazone and metformin (SPIOMET) for adolescent girls and young women with polycystic ovary syndrome: study protocol for a multicentre, randomised, double-blind, placebo-controlled, four-arm, parallel-group, phase II clinical trial
Garcia-Beltran, Cristina; Malpique, Rita; Andersen, Marianne S; Bas, Firdevs; Bassols, Judit; Darendeliler, Feyza; Díaz, Marta; Dieris, Barbara; Fanelli, Flaminia; Fröhlich-Reiterer, Elke; Gambineri, Alessandra; Glintborg, Dorte; López-Bermejo, Abel; Mann, Christopher; Marin, Silvia; Obermayer-Pietsch, Barbara; Ødegård, Rønnaug Astri; Ravn, Pernille; Reinehr, Thomas; Renzulli, Matteo; Salvador, Cristina; Singer, Viola; Vanky, Eszter Ilona; Torres, Juan Vicente; Yildiz, Melek; de Zegher, Francis; Ibáñez, Lourdes (Peer reviewed; Journal article, 2023)Background: Polycystic ovary syndrome (PCOS) is the most prevalent, chronic endocrine‑metabolic disorder of adolescents and young women (AYAs), affecting 5–10% of AYAs worldwide. There is no approved pharmacological therapy ... -
Systematic review and meta-analysis of birth outcomes in women with polycystic ovary syndrome
Bahri Khomami, Mahnaz; Hashemi, Somayeh; Shorakae, Soulmaz; Harrison, Cheryce L.; Piltonen, Terhi T.; Romualdi, Daniela; Tay, Chau Thien; Mousa, Aya; Vanky, Eszter Ilona; Teede, Helena J. (Journal article; Peer reviewed, 2024)It is unclear whether polycystic ovary syndrome (PCOS) is an independent risk factor for adverse birth outcomes in the offspring of affected women. Here, we investigate the association of PCOS with birth outcomes in the ...