Browsing NTNU Open by Author "Valla, Marit"
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Androgen receptor expression in breast cancer subtypes
Kraby, Maria Ryssdal (Master thesis, 2016)Background The androgen receptor (AR) is frequently expressed in breast cancer, and associated with good prognosis in ER-positive breast cancers. Due to its high prevalence, AR is also a possible target for therapeutic ... -
Basal markers and prognosis in luminal breast cancer
Engstrøm, Monica J; Valla, Marit; Bofin, Anna M. (Journal article; Peer reviewed, 2017)Purpose Basal marker expression in triple-negative breast cancers identifies basal-like tumours, and thus separates the TN group into two prognostic groups. However, the expression and prognostic significance of basal ... -
Characterization of FGD5 expression in primary breast cancers and lymph node metastases
Valla, Marit; Mjønes, Patricia; Engstrøm, Monica J; Ytterhus, Borgny; Bordin, Diana Lilian; van Loon, Barbara; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2018)Faciogenital dysplasia 5 (FGD5) amplification drives tumor cell proliferation, and is present in 9.5% of breast cancers. We describe FGD5 expression, assess associations between FGD5 amplification and FGD5 expression, and ... -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. (Journal article; Peer reviewed, 2017)Purpose Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ... -
Molecular subtypes of breast cancer: incidence and prognosis
Valla, Marit (Doctoral theses at NTNU;2017:276, Doctoral thesis, 2017)Forekomsten av brystkreft har over flere tiår økt i den vestlige verden, og i Norge har det vært en dobling av insidensen siden Kreftregisteret startet sin overvåkning av antall krefttilfeller i Norge i 1952. I Norge har ... -
Molecular Subtypes of Breast Cancer: Long-term Incidence Trends and Prognostic Differences
Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe (Journal article; Peer reviewed, 2016)Background: Secular trends in incidence and prognosis of molecular breast cancer subtypes are poorly described. We studied long-term trends in a population of Norwegian women born 1886–1977. Methods: A total of 52,949 ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
Klæstad, Elise; Opdahl, Signe; Engstrøm, Monica J; Ytterhus, Borgny; Wik, Elisabeth; Bofin, Anna Mary; Valla, Marit (Peer reviewed; Journal article, 2020)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 ... -
The prognostic value of androgen receptors in breast cancer subtypes
Kraby, Maria Ryssdal; Valla, Marit; Opdahl, Signe; Haugen, Olav Anton; Sawicka, Joanna Ewa; Engstrøm, Monica J; Bofin, Anna M. (Journal article; Peer reviewed, 2018)Purpose Androgen receptor (AR) expression is frequent in breast cancer and has been associated with good prognosis in several studies. The present study investigates AR-expression in relation to molecular subtypes, ...