• The bidirectional temporal relationship between headache and affective disorders: longitudinal data from the HUNT studies 

      Giri, Samita; Tronvik, Erling Andreas; Hagen, Knut (Peer reviewed; Journal article, 2022)
      Background Few prospective population-based studies have evaluated the bidirectional relationship between headache and affective disorder. The aim of this large-scale population-based follow-up study was to investigate ...
    • A biofeedback app for migraine: Development and usability study 

      Ingvaldsen, Sigrid Hegna; Tronvik, Erling Andreas; Brenner, Eiliv; Winnberg, Ingunn; Olsen, Alexander; Gravdahl, Gøril Bruvik; Stubberud, Anker (Peer reviewed; Journal article, 2021)
      Background: Biofeedback is effective in treating migraines. It is believed to have a beneficial effect on autonomous nervous system activity and render individuals resilient to stressors that may trigger a migraine. However, ...
    • Biofeedback Treatment App for Pediatric Migraine: Development and Usability Study 

      Stubberud, Anker; Tronvik, Erling Andreas; Olsen, Alexander; Gravdahl, Gøril Bruvik; Linde, Mattias (Peer reviewed; Journal article, 2020)
      Objective The objective of this study was to develop and investigate the usability of a biofeedback treatment smartphone app for adolescent migraine sufferers. Background Biofeedback is effective in treating pediatric ...
    • Clinical features of visual migraine aura: A systematic review 

      Viana, Michele; Tronvik, Erling Andreas; Do, Thien Phu; Zecca, Chiara; Hougaard, Anders (Journal article; Peer reviewed, 2019)
      Background Migraine aura (MA) is a common and disabling neurological condition, characterized by transient visual, and less frequently sensory and dysphasic aura disturbances. MA is associated with an increased risk ...
    • Cluster Headache Genomewide Association Study and Meta-Analysis Identifies Eight Loci and Implicates Smoking as Causal Risk Factor 

      Winsvold, Bendik Kristoffer Slagsvold; Harder, Aster V. E.; Ran, Caroline; Chalmer, Mona A.; Dalmasso, Maria Carolina; Ferkingstad, Egil; Tripathi, Kumar Parijat; Bacchelli, Elena; Børte, Sigrid; Fourier, Carmen; Petersen, Anja S.; Vijfhuizen, Lisanne S.; Magnusson, Sigurdur H.; O'Connor, Emer; Bjornsdottir, Gyda; Häppölä, Paavo; Wang, Yen-Feng; Callesen, Ida; Kelderman, Tim; Gallardo, Victor J; de Boer, Irene; Olofsgård, Felicia Jennysdotter; Heinze, Katja; Lund, Nunu; Thomas, Laurent Francois; Hsu, Chia-Lin; Pirinen, Matti; Hautakangas, Heidi; Ribasés, Marta; Guerzoni, Simona; Sivakumar, Prasanth; Yip, Janice; Heinze, Axel; Küçükali, Fahri; Ostrowski, Sisse R.; Pedersen, Ole B.; Kristoffersen, Espen Saxhaug; Martinsen, Amy; Artigas, María S.; Lagrata, Susie; Cainazzo, Maria Michela; Adebimpe, Joycee; Quinn, Olivia; Göbel, Carl; Cirkel, Anna; Volk, Alexander E.; Heilmann-Heimbach, Stefanie; Skogholt, Anne Heidi; Gabrielsen, Maiken Elvestad; Wilbrink, Leopoldine A.; Danno, Daisuke; Mehta, Dwij; Guðbjartsson, Daníel F.; Rosendaal, Frits Richard; Willems van Dijk, Ko; Fronczek, Rolf; Wagner, Michael; Scherer, Martin; Göbel, Hartmut; Sleegers, Kristel; Sveinsson, Olafur A.; Pani, Luca; Zoli, Michele; Ramos-Quiroga, Josep A.; Dardiotis, Efthimios; Steinberg, Anna; Riedel-Heller, Steffi; Sjöstrand, Christina; Thorgeirsson, Thorgeir E.; Stefansson, Hreinn; Southgate, Laura; Trembath, Richard C.; Vandrovcova, Jana; Noordam, Raymond; Paemeleire, Koen; Stefansson, Kari; Fann, Cathy Shen-Jang; Waldenlind, Elisabet; Tronvik, Erling Andreas; Jensen, Rigmor H.; Chen, Shih-Pin; Houlden, Henry; Terwindt, Gisela M.; Kubisch, Christian; Maestrini, Elena; Vikelis, Michail; Pozo-Rosich, Patricia; Belin, Andrea C.; Matharu, Manjit; van den Maagdenberg, Arn M.J.M.; Hansen, Thomas; Ramirez, Alfredo; Zwart, John Anker Henrik (Peer reviewed; Journal article, 2023)
      Objective The objective of this study was to aggregate data for the first genomewide association study meta-analysis of cluster headache, to identify genetic risk variants, and gain biological insights. Methods A ...
    • Continuous positive airway pressure in cluster headache: A randomized, placebo-controlled, triple-blind, crossover study 

      Gravdahl, Gøril Bruvik; Aakerøy, Lars; Stovner, Lars Jacob; Engstrøm, Morten; Müller, Kai Ivar; Bjørk, Marte-Helene; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Abstract Background Oxygen inhalation aborts cluster headache attacks, and case reports show the effect of continuous positive airway pressure. The aim of this study was to investigate the prophylactic effect of continuous ...
    • Digital Technology Biofeedback for the Prophylaxis of Pediatric Migraine 

      Stubberud, Anker (Doctoral theses at NTNU;2020:204, Doctoral thesis, 2020)
    • Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools 

      Bahrami, Shahram; Hindley, Guy Frederick Lanyon; Winsvold, Bendik K S; O'Connell, Kevin S; Frei, Oleksandr; Shadrin, Alexey; Cheng, Weiqiu; Bettella, Francesco; Rødevand, Linn; Ødegaard, Ketil Joachim; Fan, Chun C; Pirinen, Matti J; Hautakangas, Heidi M; Martinsen, Amy; Skogholt, Anne Heidi; Brumpton, Ben Michael; Willer, Cristen J; Tronvik, Erling Andreas; Kristoffersen, Espen Saxhaug; Zwart, John Anker Henrik; Nielsen, Jonas Bille; Hagen, Knut; Nilsen, Kristian Bernhard; Hveem, Kristian; Stovner, Lars Jacob; Fritsche, Lars; Thomas, Laurent; Pedersen, Linda Margareth; Gabrielsen, Maiken Elvestad; Johnsen, Marianne Bakke; Lie, Marie; Holmen, Oddgeir Lingaas; Børte, Sigrid; Stensland, Synne; Zhou, Wei; Dale, Anders; Djurovic, Srdjan; Smeland, Olav Bjerkehagen; Andreassen, Ole (Peer reviewed; Journal article, 2022)
      Migraine is three times more prevalent in people with bipolar disorder or depression. The relationship between schizophrenia and migraine is less certain although glutamatergic and serotonergic neurotransmission are ...
    • Does pain sensitivity change by migraine phase? A blinded longitudinal study 

      Hagen, Knut; Omland, Petter Moe; Stovner, Lars Jacob; Sand, Trond Halfdan; Uglem, Martin; Tronvik, Erling Andreas; Nilsen, Kristian Bernhard; Linde, Anders Mattias (Journal article; Peer reviewed, 2016)
      Objective: Studies suggest that pain thresholds may be altered before and during migraine headaches, but it is still debated if a central or peripheral dysfunction is responsible for the onset of pain in migraine. The ...
    • Effect of Spinal Cord Burst Stimulation vs Placebo Stimulation on Disability in Patients With Chronic Radicular Pain After Lumbar Spine Surgery: A Randomized Clinical Trial 

      Hara, Sozaburo; Andresen, Hege; Solheim, Ole; Carlsen, Sven Magnus; Sundstrøm, Terje; Lønne, Greger; Vangen-Lønne, Vetle; Taraldsen, Kristin; Tronvik, Erling Andreas; Øie, Lise Rystad; Gulati, Agnete Malm; Sagberg, Lisa Millgård; Jakola, Asgeir Store; Solberg, Tore; Nygaard, Øystein Petter; Salvesen, Øyvind; Gulati, Sasha (Peer reviewed; Journal article, 2022)
      Importance: The use of spinal cord stimulation for chronic pain after lumbar spine surgery is increasing, yet rigorous evidence of its efficacy is lacking. Objective: To investigate the efficacy of spinal cord burst ...
    • Epidemiology of diagnosed cluster headache in Norway 

      Vidal, Joan Crespi; Gulati, Sasha; Salvesen, Øyvind; Bratbak, Daniel Fossum; Dodick, David W; Matharu, Manjit Singh; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2022)
      Background: Cluster headache (CH) is one of the most painful conditions in humans and there is limited epidemiological data on this debilitating condition. Objectives: To describe the epidemiology of CH in Norway Methods: We ...
    • FollowTheSutures: Piloting a new way to administer onabotulinumtoxinA for chronic migraine. 

      Stovner, Lars Jacob; Hagen, Knut; Tronvik, Erling Andreas; Gravdahl, Gøril Bruvik; Burstein, Rami; Dodick, David W. (Peer reviewed; Journal article, 2022)
      Background Anatomical and experimental data indicate that onabotulinimtoxin A could be more efficient and cost-effective for treating chronic migraine with injections targeting the cranial sutures, where collaterals from ...
    • Forecasting migraine with machine learning based on mobile phone diary and wearable data 

      Stubberud, Anker; Ingvaldsen, Sigrid Hegna; Brenner, Eiliv; Winnberg, Ingunn Grøntveit; Olsen, Alexander; Gravdahl, Gøril Bruvik; Matharu, Manjit Singh; Nachev, Parashkev; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2023)
      Introduction Triggers, premonitory symptoms and physiological changes occur in the preictal migraine phase and may be used in models for forecasting attacks. Machine learning is a promising option for such predictive ...
    • Genetic Susceptibility Loci in Genomewide Association Study of Cluster Headache 

      Harder, Aster V.E.; Winsvold, Bendik K S; Noordam, Raymond; Vijfhuizen, Lisanne S.; Børte, Sigrid; Kogelman, Lisette J.A.; de Boer, Irene; Tronvik, Erling Andreas; Rosendaal, Frits; Willems van Dijk, Ko; O'Connor, Emer; Fourier, Carmen; Thomas, Laurent; Kristoffersen, Espen Saxhaug; Fronczek, Rolf; Pozo-Rosich, Patricia; Jensen, Rigmor; Ferrari, Michel D.; Hansen, Thomas; Zwart, John-Anker; Terwindt, Gisela M.; van den Maagdenberg, Arn M.J.M (Peer reviewed; Journal article, 2021)
      Objective Identifying common genetic variants that confer genetic risk for cluster headache. Methods We conducted a case–control study in the Dutch Leiden University Cluster headache neuro-Analysis program (LUCA) study ...
    • Gir ACE-hemmere og angiotensinreseptorantagonister økt risiko for alvorlig covid-19? 

      Aamodt, Anne Hege; Bjørk, Marte-Helene; Tronvik, Erling Andreas; Buanes, Eirik Alnes; Stovner, Lars Jacob; Atar, Dan (Peer reviewed; Journal article, 2020)
      Hypertensjon og diabetes mellitus er risikofaktorer for alvorlig covid-19. Det er blitt reist spørsmål om hvorvidt denne assosiasjonen er relatert til bruk av ACE-hemmere og angiotensin II-reseptorblokkere.
    • The impact of topiramate, botulinum toxin type A, and CGRP-antibodies on medication overuse headache in patients with chronic migraine: A protocol for systematic review and meta-analysis 

      Giri, Samita; Tronvik, Erling Andreas; Linde, Mattias; Hagen, Knut (Peer reviewed; Journal article, 2022)
      Medication overuse headache (MOH) is defined as headache occurring ≥15 days/month developing as a consequence of regular overuse of acute or symptomatic headache medication for more than 3 months. MOH is present in more ...
    • Is pituitary MRI screening necessary in cluster headache? 

      Grangeon, Lou; OConnor, Emer; Danno, Daisuke; Ngoc, Thanh Mai Pham; Cheema, Sanjay; Tronvik, Erling Andreas; Davagnanam, Indran; Matharu, Manjit (Peer reviewed; Journal article, 2021)
      Objective To determine the prevalence and clinical predictors of pituitary adenomas in cluster headache patients, in order to determine the necessity of performing dedicated pituitary magnetic resonance imaging in patients ...
    • Is there a causal relationship between stress and migraine? Current evidence and implications for management 

      Stubberud, Anker; Buse, Dawn C.; Kristoffersen, Espen Saxhaug; Linde, Mattias; Tronvik, Erling Andreas (Peer reviewed; Journal article, 2021)
      Background The purpose of this narrative review is to examine the literature investigating a causal relationship between stress and migraine and evaluate its implications for managing migraine. Methods PubMed, PsycINFO and ...
    • Lack of association between cluster headache and PER3 clock gene polymorphism 

      Ofte, Hilde Karen; Tronvik, Erling Andreas; Alstadhaug, Karl Bjørnar (Journal article; Peer reviewed, 2016)
      Background: Cluster headache (CH) is regarded as a chronobiological disorder. The hypothalamic biological clock may thus be involved in the pathophysiology, but few studies have actually investigated this in CH patients. ...
    • Machine prescription for chronic migraine 

      Stubberud, Anker; Gray, Robert; Tronvik, Erling Andreas; Matharu, Manjit Singh; Nachev, Parashkev (Peer reviewed; Journal article, 2022)
      Responsive to treatment individually, chronic migraine remains strikingly resistant collectively, incurring the second-highest population burden of disability worldwide. A heterogeneity of responsiveness, requiring ...