Blar i NTNU Open på forfatter "Tranulis, Michael A."

Viser treff 1-6 av 6

    • Comparison of organic and conventional food and food Production. Part IV: Human health – hygiene and pathogens 

      Lassen, Jørgen Fredrik; Kapperud, Georg; Lunestad, Bjørn Tore; Robertson, Lucy Jane; Tranulis, Michael A.; Yazdankhah, Siamak Pour; Andreassen, Åshild Kristine; Arukwe, Augustine; Bøe, Knut Egil; Eckner, Karl Friedrich; Haugen, Margaretha; Hemre, Gro Ingunn; Krogdahl, Åshild; Källqvist, Torsten; Nesbakken, Truls; Nygård, Karin Maria; Næss, Bjørn; Skåre, Janneche Utne; Steffensen, Inger-Lise; Sundheim, Leif; Torrissen, Ole; Tryland, Morten; Alexander, Jan (VKM Report;, Research report, 2014)

    • Demyelinating polyneuropathy in goats lacking prion protein 

      Skedsmo, Fredrik Strebel; Malachin, Giulia; Våge, Dag Inge; Hammervold, Mie Marie; Salvesen, Øyvind; Ersdal, Cecilie; Ranheim, Birgit; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Bruheim, Per; Jäderlund, Karin Hultin; Matiasek, Kaspar; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2019)
      Studies in mice with ablation of Prnp, the gene that encodes the cellular prion protein (PrPC), have led to the hypothesis that PrPC is important for peripheral nerve myelin maintenance. Here, we have used a nontransgenic ...

    • DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease 

      Scheffler, Katja; Jalland, Clara Maria Osnes; Benestad, Sylvie L.; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Peer reviewed; Journal article, 2020)
      The DNA glycosylase Neil2 is a member of the base excision repair (BER) family of enzymes, which are important for repair of oxidative DNA damage. Specifically, Neil2 participates in repair of oxidized bases in single-stranded ...

    • Impaired NDRG1 functions in Schwann cells cause demyelinating neuropathy in a dog model of Charcot-Marie-Tooth type 4D 

      Skedsmo, Fredrik; Espenes, Arild; Tranulis, Michael A.; Matiasek, Kaspar; Gunnes, Gjermund; Bjerkås, Inge; Moe, Lars; Røed, Susan Skogtvedt; Berendt, Mette; Fredholm, Merete; Rohdin, Cecilia; Shelton, G. Diane; Bruheim, Per; Stafsnes, Marit Hallvardsdotter; Bartosova, Zdenka; Hermansen, Lene Cecilie; Stigen, Øyvind; Jäderlund, Karin Hultin (Peer reviewed; Journal article, 2021)
      Mutations in the N-myc downstream-regulated gene 1 (NDRG1) cause degenerative polyneuropathy in ways that are poorly understood. We have investigated Alaskan Malamute dogs with neuropathy caused by a missense mutation in ...

    • Neil3 induced neurogenesis protects against prion disease during the clinical phase 

      Jalland, Clara Maria Osnes; Scheffler, Katja; Benestad, Sylvie Lafond; Moldal, Torfinn; Ersdal, Cecilie; Gunnes, Gjermund; Suganthan, Rajikala; Bjørås, Magnar; Tranulis, Michael A. (Journal article; Peer reviewed, 2016)
      Base excision repair (BER) is the major pathway for repair of oxidative DNA damage. Mice with genetic knockout of the BER enzyme Neil3 display compromised neurogenesis in the sub-ventricular zone of the lateral ventricle ...

    • Stress resilience of spermatozoa and blood mononuclear cells without prion protein 

      Reiten, Malin Rokseth; Malachin, Giulia; Kommisrud, Elisabeth; Østby, Gunn Charlotte; Waterhouse, Karin Elisabeth; Krogenæs, Anette Kristine; Kusnierczyk, Anna; Bjørås, Magnar; Jalland, Clara Maria Osnes; Nekså, Liv Heidi; Røed, Susan Skogtvedt; Stenseth, Else-Berit; Myromslien, Frøydis Deinboll; Zeremichael, Teklu Tewoldebrhan; Bakkebø, Maren Kolltveit; Espenes, Arild; Tranulis, Michael A. (Journal article; Peer reviewed, 2018)
      The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC. ...