Browsing NTNU Open by Author "Thorsby, Per Medbøe"

Now showing items 1-11 of 11

    • Alterations in the Vitamin D endocrine system during pregnancy: A longitudinal study of 855 healthy Norwegian women 

      Gustafsson, Miriam; Romundstad, Pål Richard; Stafne, Signe Nilssen; Helvik, Anne-Sofie; Stunes, Astrid Kamilla; Mørkved, Siv; Salvesen, Kjell Å; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2018)
      To ensure optimal calcium accrual in the fetal skeleton, a substantial rise occurs in 1,25-dihydroxyvitamin D (1,25(OH)2D), but is dependent on sufficient 25-hydroxyvitamin (25(OH)D). Large longitudinal studies addressing ...

    • Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency 

      Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Joakimsen, Ragnar Martin; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2019)
      In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D ...

    • Evidence of impaired bone quality in men with type 1 diabetes: A cross-sectional study 

      Syversen, Unni; Mosti, Mats Peder; Mynarek, Ida Maria; Vedal, Trude Seselie Jahr; Aasarød, Kristin Matre; Basso, Trude; Reseland, Janne E.; Thorsby, Per Medbøe; Asvold, Bjorn O.; Eriksen, Erik Fink; Stunes, Astrid Kamilla (Peer reviewed; Journal article, 2021)
      Objective Type 1 diabetes (T1D) is associated with substantial fracture risk. Bone mineral density (BMD) is, however, only modestly reduced, suggesting impaired bone microarchitecture and/or bone material properties. Yet, ...

    • Long-Term improvement after combined immunomodulation in early post-H1N1 vaccination narcolepsy 

      Viste, Rannveig; Soosai, Joseph; Vikin, Truls; Thorsby, Per Medbøe; Nilsen, Kristian Bernhard; Knudsen, Stine (Journal article; Peer reviewed, 2017)
      We previously described the possible clinical effects of early monotherapeutic IV-immunomodulation (IVIg) treatment in sporadic1 but not in postH1N1 vaccination narcolepsy type 1 (NT1).2 We report here an early post-H1N1 ...

    • Maternal serum retinol, 25(OH)D and 1,25(OH)2D concentrations during pregnancy and peak bone mass and trabecular bone score in adult offspring at 26-year follow-up 

      Balasuriya, Chandima Nirupa Dilruks; Larose, Tricia L; Mosti, Mats Peder; Evensen, Kari Anne Indredavik; Jacobsen, Geir Wenberg; Thorsby, Per Medbøe; Stunes, Astrid Kamilla; Syversen, Unni (Journal article; Peer reviewed, 2019)
      Background Vitamin A and D deficiency is prevalent in pregnant women worldwide. Both vitamins are involved in fetal skeletal development. A positive association between maternal vitamin D levels and offspring bone mineral ...

    • New reference intervals for cortisol, cortisol binding globulin and free cortisol index in women using ethinyl estradiol 

      Panton, Kristine Kollerøs; Mikkelsen, Gustav; Irgens, Wenche Elna Øiestad; Hovde, Ann Kristin; Killingmo, Marte Wien; Øien, Monja Airin; Thorsby, Per Medbøe; Åsberg, Arne (Peer reviewed; Journal article, 2019)
      Healthy women using contraceptives containing a low dose of an estrogen may have a higher serum concentration of cortisol (s-cortisol) and cortisol binding globulin (s-CBG) than the commonly used upper reference limits. ...

    • Presence of anti-GAD in a non-diabetic population of adults; time dynamics and clinical influence: results from the HUNT study 

      Sørgjerd, Elin Pettersen; Thorsby, Per Medbøe; Torjesen, Peter A; Skorpen, Frank; Kvaløy, Kirsti; Grill, Valdemar Erik Robert (Peer reviewed; Journal article, 2015)
      Background It is well known that anti-GAD (glutamic acid decarboxylase) serves as a marker for development of autoimmune diabetes in adults. On the other hand, the clinical implications of anti-GAD positivity in persistently ...

    • Smoking and other determinants of bone turnover 

      Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2019)
      The balance between bone resorption and formation may be assessed by measurement of bone turnover markers (BTMs), like carboxyl-terminal cross-linked telopeptide of type 1 collagen (CTX-1) and procollagen type 1 amino-terminal ...

    • Smoking, use of smokeless tobacco, HLA genotypes and incidence of latent autoimmune diabetes in adults 

      Edstorp, Jessica; Wei, Yuxia; Ahlqvist, Emma; Alfredsson, Lars; Grill, Valdemar Erik Robert; Groop, Leif; Rasouli, Bahareh; Sørgjerd, Elin Pettersen; Thorsby, Per Medbøe; Tuomi, Tiinamaija; Åsvold, Bjørn Olav; Carlsson, Sofia (Peer reviewed; Journal article, 2022)
      Aims/hypotheses Smoking and use of smokeless tobacco (snus) are associated with an increased risk of type 2 diabetes. We investigated whether smoking and snus use increase the risk of latent autoimmune diabetes in adults ...

    • Stress responses to repeated captures in a wild ungulate 

      Trondrud, Liv Monica; Ugland, Cassandra Regine; Ropstad, Erik; Loe, Leif Egil; Albon, Steve; Stien, Audun; Evans, Alina; Thorsby, Per Medbøe; Veiberg, Vebjørn; Irvine, R. Justin; Pigeon, Gabriel (Peer reviewed; Journal article, 2022)
      While capture-mark-recapture studies provide essential individual-level data in ecology, repeated captures and handling may impact animal welfare and cause scientific bias. Evaluating the consequences of invasive methodologies ...

    • The effect of an exercise program in pregnancy on vitamin D status among healthy, pregnant Norwegian women: a randomized controlled trial 

      Gustafsson, Miriam K.; Romundstad, Pål Richard; Stafne, Signe Nilssen; Helvik, Anne-Sofie; Stunes, Astrid Kamilla; Mørkved, Siv; Salvesen, Kjell Å; Thorsby, Per Medbøe; Mosti, Mats Peder; Syversen, Unni (Journal article; Peer reviewed, 2019)
      Background Vitamin D insufficiency is common in pregnant women worldwide. Regular prenatal exercise is considered beneficial for maternal and fetal health. There is a knowledge gap regarding the impact of prenatal ...