Browsing NTNU Open by Author "Thorgersen, Ebbe Billmann"

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Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy

Thorgersen, Ebbe Billmann; Asvall, Jørund; Frøysnes, Ida Storhaug; Schjalm, Camilla; Larsen, Stein Gunnar; Dueland, Svein; Andersson, Yvonne; Fodstad, Øystein; Mollnes, Tom Eirik; Flatmark, Kjersti (Journal article; Peer reviewed, 2021)

Background - Despite extensive cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC), most patients with resectable peritoneal metastases from colorectal cancer experience disease relapse. MOC31PE ...
Normothermic Machine Perfusion Reconstitutes Porcine Kidney Tissue Metabolism But Induces an Inflammatory Response, Which Is Reduced by Complement C5 Inhibition

de Boer, Eline; Sokolova, Marina; Jager, Neeltina M.; Schjalm, Camilla; Weiss, Marc G.; Liavåg, Olav Magnus Ivar; Maassen, Hanno; van Goor, Harry; Thorgersen, Ebbe Billmann; Pettersen, Kristin; Christiansen, Dorte; Ludviksen, Judith K; Jespersen, Bente; Mollnes, Tom Eirik; Leuvenink, Henri G. D.; Pischke, Soeren (Peer reviewed; Journal article, 2024)

Normothermic machine perfusion (NMP) is a clinical strategy to reduce renal ischemia-reperfusion injury (IRI). Optimal NMP should restore metabolism and minimize IRI induced inflammatory responses. Microdialysis was used ...