Browsing NTNU Open by Author "Teti, Giuseppe"
Now showing items 1-3 of 3
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Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation
Lentini, Germana; Famà, Agata; De Gaetano, Giuseppe Valerio; Coppolino, Francesco; Mahjoub, Ahlem Khachroub; Ryan, Liv; Lien, Egil; Espevik, Terje; Beninati, Concetta; Teti, Giuseppe (Peer reviewed; Journal article, 2023)During differentiation, neutrophils undergo a spontaneous pro-inflammatory program that is hypothesized here to be under caspase-8 control. In mice, intraperitoneal administration of the caspase-8 inhibitor z-IETD-fmk is ... -
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Teti, Giuseppe; Sharma, Aditya Kumar; Kandasamy, Richard Kumaran; Sporsheim, Bjørnar; Starheim, Kristian K.; Golenbock, Douglas T.; Stenmark, Harald; McCaffrey, Mary; Espevik, Terje; Husebye, Harald (Journal article; Peer reviewed, 2019)Phagocytosis is a complex process that eliminates microbes and is performed by specialised cells such as macrophages. Toll-like receptor 4 (TLR4) is expressed on the surface of macrophages and recognizes Gram-negative ... -
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
Skjesol, Astrid; Yurchenko, Mariya; Bösl, Korbinian; Gravastrand, Caroline S.; Nilsen, Kaja Elisabeth; Grøvdal, Lene Melsæther; Agliano, Federica; Patane, Francesco; Lentini, Germana; Kim, Hera; Teti, Giuseppe; Sharma, Aditya Kumar; Kandasamy, Richard Kumaran; Sporsheim, Bjørnar; Starheim, Kristian K.; Golenbock, Douglas T.; Stenmark, Harald; McCaffrey, Mary; Espevik, Terje; Husebye, Harald (Peer reviewed; Journal article, 2019)Phagocytosis is a complex process that eliminates microbes and is performed by specialised cells such as macrophages. Toll-like receptor 4 (TLR4) is expressed on the surface of macrophages and recognizes Gram-negative ...