• Are the Neuroprotective Effects of Exercise Training Systemically Mediated? 

      Tari, Atefe R; Norevik, Cecilie Skarstad; Scrimgeour, Nathan Robert; Kobro-Flatmoen, Asgeir; Storm-Mathisen, Jon; Bergersen, Linda Hildegard; Wrann, Christiane D; Selbæk, Geir; Kivipelt, Miia; Moreira, Jose Bianco Nascimento; Wisloff, Ulrik (Journal article; Peer reviewed, 2019)
      To date there is no cure available for dementia, and the field calls for novel therapeutic targets. A rapidly growing body of literature suggests that regular endurance training and high cardiorespiratory fitness attenuate ...
    • Can exercise training teach us how to treat Alzheimer's disease? 

      Huuha, Aleksi Matias; Norevik, Cecilie Skarstad; Moreira, Jose Bianco Nascimento; Kobro-Flatmoen, Asgeir; Scrimgeour, Nathan Robert; Kivipelto, Miia; Van Praag, Henriette; Ziaei, Maryam; Sando, Sigrid Botne; Wisløff, Ulrik; Tari, Atefe R (Peer reviewed; Journal article, 2022)
      Alzheimer’s disease (AD) is the most common cause of dementia and there is currently no cure. Novel approaches to treat AD and curb the rapidly increasing worldwide prevalence and costs of dementia are needed. Physical ...
    • Does exercise training or exercised blood affect gene expression in the brain of a rat model of Alzheimer's disease? 

      Helgeland, Torild Klæhaug; Riseth, Marte (Bachelor thesis, 2020)
      Alzheimers sykdom er den mest utbredte formen for demens i verden. Prevalensen er forventet å øke i fremtiden som et resultat av en aldrende verdensbefolkning. Alzheimers sykdom er en kronisk neurodegenerativ sykdom som ...
    • Effect of 5 years of exercise training on the cardiovascular risk profile of older adults: the Generation 100 randomized trial 

      Letnes, Jon Magne; Berglund, Ida Johnsen; Johnson, Kristin Espolin; Dalen, Håvard; Nes, Bjarne; Lydersen, Stian; Viken, Hallgeir; Hassel, Erlend; Steinshamn, Sigurd Loe; Vesterbekkmo, Elisabeth Kleivhaug; Støylen, Asbjørn; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Ingebrigtsen, Jan Erik; Bucher Sandbakk, Silvana; Carlsen, Trude; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik; Stensvold, Dorthe (Peer reviewed; Journal article, 2021)
      Aims The aim of this study was to compare the effects of 5 years of supervised exercise training (ExComb), and the differential effects of subgroups of high-intensity interval training (HIIT) and moderate-intensity continuous ...
    • Effect of exercise training for five years on all cause mortality in older adults-The Generation 100 study: Randomised controlled trial 

      Stensvold, Dorthe; Viken, Hallgeir; Steinshamn, Sigurd Loe; Dalen, Håvard; Støylen, Asbjørn; Loennechen, Jan Pål; Reitlo, Line Skarsem; Zisko, Nina; Bækkerud, Fredrik Hjulstad; Tari, Atefe R; Bucher Sandbakk, Silvana; Carlsen, Trude; Ingebrigtsen, Jan Erik; Lydersen, Stian; Mattsson, Erney; Anderssen, Sigmund Alfred; Singh, Maria A. Fiatarone; Coombes, Jeff S.; Skogvoll, Eirik; Vatten, Lars Johan; Helbostad, Jorunn L.; Rognmo, Øivind; Wisløff, Ulrik (Peer reviewed; Journal article, 2020)
      Objective To evaluate the effect of five years of supervised exercise training compared with recommendations for physical activity on mortality in older adults (70-77 years). Design Randomised controlled trial. Setting ...
    • How to Be 80 Year Old and Have a VO2max of a 35 Year Old 

      Karlsen, Trine; Leinan, Ingeborg Megård; Bækkerud, Fredrik Hjulstad; Lundgren, Kari Margrethe; Tari, Atefe R; Steinshamn, Sigurd Loe; Støylen, Asbjørn; Rognmo, Øivind (Peer reviewed; Journal article, 2015)
      Background. To discuss the cardiovascular and pulmonary physiology and common risk factors of an 80-year-old man with a world record maximal oxygen uptake of 50 mL·kg−1·min−1. Methods. Case report. Results. His maximal ...
    • Personal Activity Intelligence and Ischemic Heart Disease in a Healthy Population: China Kadoorie Biobank Study 

      Hammer, Pål; Tari, Atefe R; Franklin, Barry A.; Wen, Chi-Pang; Wisløff, Ulrik; Nauman, Javaid (Peer reviewed; Journal article, 2022)
      Background: Personal Activity Intelligence (PAI) is a physical activity metric that translates heart rate during physical activity into a simple score, where a weekly score of 100 or greater is associated with a lower risk ...
    • Safety and efficacy of plasma transfusion from exercise - trained donors in patients with early Alzheimer’s disease: protocol for the ExPlas study 

      Tari, Atefe R; Berg, Helene Haugen; Videm, Vibeke; Bråthen, Geir; White, Linda Rosemary; Røsbjørgen, Ragnhild; Scheffler, Katja; Dalen, Håvard; Holte, Espen; Håberg, Asta Kristine; Selbæk, Geir; Lydersen, Stian; Duezel, Emrah; Bergh, Sverre; Logan-halvorsrud, Kjell Rune; Sando, Sigrid Botne; Wisløff, Ulrik (Peer reviewed; Journal article, 2022)
      Introduction Given that exercise training reduces the risk of developing Alzheimer’s disease (AD), induces changes in the blood composition and has widespread systemic benefits, it is reasonable to hypothesise that exercised ...
    • Temporal changes in cardiorespiratory fitness and risk of dementia incidence and mortality: a population-based prospective cohort study 

      Tari, Atefe R; Nauman, Javaid; Zisko, Nina; Skjellegrind, Håvard; Bosnes, Ingunn; Bergh, Sverre; Stensvold, Dorthe; Selbæk, Geir; Wisløff, Ulrik (Journal article; Peer reviewed, 2019)
      Cardiorespiratory fitness is associated with risk of dementia, but whether temporal changes in cardiorespiratory fitness influence the risk of dementia incidence and mortality is still unknown. We aimed to study whether ...
    • Temporal changes in personal activity intelligence and the risk of incident dementia and dementia related mortality: A prospective cohort study (HUNT) 

      Tari, Atefe R; Selbæk, Geir; Franklin, Barry A.; Bergh, Sverre; Skjellegrind, Håvard; Sallis, Robert E.; Bosnes, Ingunn; Stordal, Eystein; Ziaei, Maryam; Lydersen, Stian; Kobro-Flatmoen, Asgeir; Huuha, Aleksi Matias; Nauman, Javaid; Wisløff, Ulrik (Peer reviewed; Journal article, 2022)
      Background The Personal Activity Intelligence (PAI) translates heart rate during daily activity into a weekly score. Obtaining a weekly PAI score ≥100 is associated with reduced risk of premature morbidity and mortality ...