Blar i NTNU Open på forfatter "Tøndervik, Anne"
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Biosynthesis and Function of Long Guluronic Acid-Blocks in Alginate Produced by Azotobacter vinelandii
Aarstad, Olav Andreas; Stanisci, Annalucia; Sætrom, Gerd Inger; Tøndervik, Anne; Sletta, Håvard; Aachmann, Finn Lillelund; Skjåk-Bræk, Gudmund (Journal article; Peer reviewed, 2019)With the present accessibility of algal raw material, microbial alginates as a source for strong gelling material are evaluated as an alternative for advanced applications. Recently, we have shown that alginate from algal ... -
Chitosan as a wound dressing starting material: antimicrobial Properties and mode of action
Matica, Mariana Adina; Aachmann, Finn Lillelund; Tøndervik, Anne; Sletta, Håvard; Ostafe, Vasile (Journal article; Peer reviewed, 2019)Fighting bacterial resistance is one of the concerns in modern days, as antibiotics remain the main resource of bacterial control. Data shows that for every antibiotic developed, there is a microorganism that becomes ... -
Development of mannuronan C-5 epimerases to perform in vitro tailoring and upgrading of alginates
Stanisci, Annalucia (Doctoral theses at NTNU;2017:325, Doctoral thesis, 2017) -
Exploiting mannuronan C-5 epimerases in commercial alginate production
Tøndervik, Anne; Aarstad, Olav Andreas; Aune, Randi; Maleki, Susan; Rye, Philip D; Dessen, Arne; Skjåk-Bræk, Gudmund; Sletta, Håvard (Peer reviewed; Journal article, 2020)Alginates are one of the major polysaccharide constituents of marine brown algae in commercial manufacturing. However, the content and composition of alginates differ according to the distinct parts of these macroalgae and ... -
Identification of a Pivotal Residue for Determining the Block Structure-Forming Properties of Alginate C-5 Epimerases
Stanisci, Annalucia; Tøndervik, Anne; Gaardløs, Margrethe; Lervik, Anders; Skjåk-Bræk, Gudmund; Sletta, Håvard; Aachmann, Finn Lillelund (Peer reviewed; Journal article, 2020)Alginate is a linear copolymer composed of 1→4 linked β-d-mannuronic acid (M) and its epimer α-l-guluronic acid (G). The polysaccharide is first produced as homopolymeric mannuronan and subsequently, at the polymer level, ... -
Identification of Regulatory Genes and Metabolic Processes Important for Alginate Biosynthesis in Azotobacter vinelandii by Screening of a Transposon Insertion Mutant Library
Mærk, Mali; Jakobsen, Øyvind Mejdell; Sletta, Håvard; Klinkenberg, Geir; Tøndervik, Anne; Ellingsen, Trond Erling; Valla, Svein; Ertesvåg, Helga (Journal article; Peer reviewed, 2020)Azotobacter vinelandii produces the biopolymer alginate, which has a wide range of industrial and pharmaceutical applications. A random transposon insertion mutant library was constructed from A. vinelandii ATCC12518Tc in ... -
In vitro screening of the prebiotic properties of the marine polysaccharides alginate, laminarin and fucoidan extracted from brown macroalgae
Skogli, Ravina Jassal (Master thesis, 2021)Med en økende verdens befolkning, har etterspørselen etter mat og fôr økt. Dette har gjort det nødvendig å utforske andre alternativer for mat ressurser og matproduksjonsområder med god kapasitet og et mindre behov for ... -
Mannuronan C-5 Epimerases Suited for Tailoring of Specific Alginate Structures Obtained by High-Throughput Screening of an Epimerase Mutant Library
Tøndervik, Anne; Klinkenberg, Geir; Aachmann, Finn Lillelund; Svanem, Britt Iren Glærum; Ertesvåg, Helga; Ellingsen, Trond Erling; Valla, Svein; Skjåk-Bræk, Gudmund; Sletta, Håvard (Journal article; Peer reviewed, 2013)The polysaccharide alginate is produced by brown algae and some bacteria and is composed of the two monomers, β-d-mannuronic acid (M) and α-l-guluronic acid (G). The distribution and composition of M/G are important for ... -
Mode of action and catalytic mechanisms of alginatemodifying enzymes Insights from the mannuronan C-5 epimerases and a bifunctional epimerase/lyase from Azotobacter vinelandii
Gaardløs, Margrethe (Doctoral theses at NTNU;2021:200, Doctoral thesis, 2021)Enzymes are biological catalysts that work efficiently and specifically to make life possible. Among their countless tasks in living organisms, they are responsible for the diversity of material properties found in nature. ... -
Structural and functional characterization of the R-modules in alginate C-5 epimerases AlgE4 and AlgE6 from Azotobacter vinelandii
Buchinger, Edith; Knudsen, Daniel H.; Behrens, Manja A.; Pedersen, Jan Skov; Aarstad, Olav Andreas; Tøndervik, Anne; Valla, Svein; Skjåk-Bræk, Gudmund; Wimmer, Reinhard; Aachmann, Finn Lillelund (Journal article; Peer reviewed, 2014)The bacterium Azotobacter vinelandii produces a family of seven secreted and calcium-dependent mannuronan C-5 epimerases (AlgE1–7). These epimerases are responsible for the epimerization of β-d-mannuronic acid (M) to ... -
Studier av biofilmdannelse hos Pseudomonas species ved forskjellige dyrkingsmetoder
Storvoll, Eirin (Master thesis, 2011)SINTEF har en konsernsatsing innenfor systembiologi og dette omfatter blant annet forståelse og bekjempelse av biofilmer. Biofilm kan forårsake skader innenfor medisin, matindustri, havbruk og industri. På en annen side ...