Blar i NTNU Open på forfatter "Syversen, Unni"
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Acute effects of strength and endurance training on bone turnover markers in young adults and elderly men
Stunes, Astrid Kamilla; Brobakken, Cathrine Langlie; Sujan, Md Abu Jafar; Aagård, Norun; Brevig, Martin Siksjø; Wang, Eivind; Syversen, Unni; Mosti, Mats Peder (Peer reviewed; Journal article, 2022)Context: Exercise is recognized as an important strategy to prevent bone loss, but its acute effects on bone turnover markers (BTMs) and related markers remain uncertain. Objective: To assess the acute effects of two ... -
Adiponectin prevents orthodontic tooth movement in rats
Haugen, Sigrid; Aasarød, Kristin Matre; Stunes, Astrid Kamilla; Mosti, Mats Peder; Franzen, Tanya Jeanette; Vandevska-Radunovic, Vaska; Syversen, Unni; Reseland, Janne Elin (Journal article; Peer reviewed, 2017)Objective The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats. Materials and methods The maxillary right first molar of male Wistar rats ... -
Adiponectin reduces bone stiffness; verified in a 3D artificial human bone model in vitro
Haugen, Sigrid; He, Jianying; Sundaresan, Alamelu; Stunes, Astrid Kamilla; Aasarød, Kristin Matre; Tiainen, Hanna; Syversen, Unni; Skallerud, Bjørn Helge; Reseland, Janne Elin (Journal article; Peer reviewed, 2018)Primary human osteoblasts and osteoclasts incubated in a rotating coculture system without any scaffolding material, form bone-like tissue that may be used to evaluate effects of various compounds on mechanical strength. ... -
Alendronate and omeprazole in combination reduce angiogenic and growth signals from osteoblasts
Kruger, Tormod Bjartveit; Herlofson, Bente Brokstad; Lian, Aina-Mari; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2021)Objective: Due to gastrointestinal side effects of oral bisphosphonates (BPs), proton pump inhibitors (PPIs) are often prescribed. PPIs may enhance the risk of osteonecrosis of the jaw, a rare side effect of BPs. Therefore, ... -
Alterations in the Vitamin D endocrine system during pregnancy: A longitudinal study of 855 healthy Norwegian women
Gustafsson, Miriam; Romundstad, Pål Richard; Stafne, Signe Nilssen; Helvik, Anne-Sofie; Stunes, Astrid Kamilla; Mørkved, Siv; Salvesen, Kjell Å; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2018)To ensure optimal calcium accrual in the fetal skeleton, a substantial rise occurs in 1,25-dihydroxyvitamin D (1,25(OH)2D), but is dependent on sufficient 25-hydroxyvitamin (25(OH)D). Large longitudinal studies addressing ... -
An experimental and numerical study of cortical bone at the macro and Nano-scale: Evaluation of long-term Proton Pump Inhibitor treatment on bone properties
Ramezanzadehkoldeh, Masoud (Doctoral theses at NTNU;2017:208, Doctoral thesis, 2017) -
Anti-osteoporosis drug use: too little, too much, or just right? The HUNT study, Norway
Hoff, Mari; Skurtveit, Svetlana; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Skovlund, Eva; Abrahamsen, Bo; Forsmo, Siri; Schei, Berit (Journal article; Peer reviewed, 2018)Summary Use of anti-osteoporotic drugs (AODs) was examined in a Norwegian population 50–85 years. Among them with Fracture Risk Assessment Tool (FRAX) score for major osteoporotic fracture ≥ 20, 25% of the women and 17% ... -
Associations between maternal and offspring glucose metabolism: A 9-year follow-up study
Nyen, Sigrid Langfeldt (Master thesis, 2023) -
Awareness of cervical cancer and prevalence of human papillomavirus and other sexually transmitted infections among women in rural Nepal.: Implications for future cervical cancer prevention in Nepal
Shakya, Sunila (Doctoral theses at NTNU;2017:87, Doctoral thesis, 2017)Cervical cancer is a leading cause of cancer deaths among women in Nepal. Limited information is available on public awareness on cervical cancer, the prevalence of its causative agents and associated risk factors. No ... -
Cortical hand bone porosity and its association with distal radius Fracture in middle aged and elderly women
Dhainaut, Alvilde; Hoff, Mari; Syversen, Unni; Haugeberg, Glenn (Journal article; Peer reviewed, 2013)Objective: Reduced bone mineral density (BMD), assessed by Dual Energy X-ray absorptiometry (DXA), is a well-known risk factor for fragility fracture. A large proportion of patients with fracture have only slightly ... -
Developmental Origins of Disease: Influence of low birth weight and maternal vitamin A and D status on offspring skeletal health and metabolic outcomes at adulthood
Balasuriya, Chandima N.D. (Doctoral theses at NTNU;2018:221, Doctoral thesis, 2018)Developmental origins of adult health and disease (DOHaD) has gained increased attention during the past few decades. Birth size reflects the prenatal environment, and there is substantial evidence that low birth weight ... -
Diabetes Prevalence and Associated Risk Factors among Women in a Rural District of Nepal Using HbA1c as a Diagnostic Tool: A Population-Based Study
Yogal, Chandra; Shakya, Sunila; Karmarcharya, Biraj; Koju, Rajendra; Stunes, Astrid Kamilla; Mosti, Mats Peder; Gustafsson, Miriam K.; Åsvold, Bjørn Olav; Schei, Berit; Syversen, Unni (Peer reviewed; Journal article, 2022)Given the scarcity of data on diabetes prevalence and associated risk factors among women in rural Nepal, we aimed to examine this, using glycated hemoglobin (HbA1c) as a diagnostic tool. A cross-sectional survey addressing ... -
Do patients with gastroesophageal reflux disease exhibit compromised bone quality prior to proton pump inhibitor therapy?
Aasarød, Kristin Matre; Mosti, Mats Peder; Finstad, Malin T.; Stunes, Astrid Kamilla; Fossmark, Reidar; Syversen, Unni (Peer reviewed; Journal article, 2021)Patients with gastroesophageal reflux disease (GERD) are routinely treated with proton pump inhibitors (PPIs), despite many reports of increased fracture risk associated with PPI use. Notably, the skeletal properties in ... -
Does treatment with bisphosphonates protect against fractures in real life? The HUNT study, Norway
Hoff, Mari; Skovlund, Eva; Meyer, Haakon E; Langhammer, Arnulf; Søgaard, Anne-Johanne; Syversen, Unni; Holvik, Kristin; Abrahamsen, Bo; Schei, Berit (Peer reviewed; Journal article, 2021)Summary Bisphosphonates reduce fractures in randomized controlled trials (RCT); however, there is less information from real life. In our population including 14,990 women and 13,239 men, use of bisphosphonates reduced ... -
Effects of vitamin D supplementation on bone turnover markers and other bone-related substances in subjects with vitamin D deficiency
Jorde, Rolf; Stunes, Astrid Kamilla; Kubiak, Julia Magdalena; Joakimsen, Ragnar Martin; Grimnes, Guri; Thorsby, Per Medbøe; Syversen, Unni (Journal article; Peer reviewed, 2019)In observational studies, vitamin D deficiency is a risk factor for low bone density and future fractures, whereas a causal relation has been difficult to show in randomized controlled trials (RCTs). Similarly, vitamin D ... -
Evidence of impaired bone quality in men with type 1 diabetes: A cross-sectional study
Syversen, Unni; Mosti, Mats Peder; Mynarek, Ida Maria; Vedal, Trude Seselie Jahr; Aasarød, Kristin Matre; Basso, Trude; Reseland, Janne E.; Thorsby, Per Medbøe; Asvold, Bjorn O.; Eriksen, Erik Fink; Stunes, Astrid Kamilla (Peer reviewed; Journal article, 2021)Objective Type 1 diabetes (T1D) is associated with substantial fracture risk. Bone mineral density (BMD) is, however, only modestly reduced, suggesting impaired bone microarchitecture and/or bone material properties. Yet, ... -
Exploring the relationship between bone density and severity of distal radius fragility fracture in women
Dhainaut, Alvilde; Daibes, Kamil; Odinsson, Adalstein; Hoff, Mari; Syversen, Unni; Haugeberg, Glenn (Journal article; Peer reviewed, 2014)Background Bone mineral density (BMD) has been shown to be a consistent and independent risk factor for distal radius fracture. Inconsistent data have been reported on the association between BMD and severity of distal ... -
Frequency of risk factors and long-term complications in a female population with previously diagnosed diabetes mellitus in rural Nepal
Tingulstad, Katharina Antonia Kocheise (Master thesis, 2017)Background: Diabetes mellitus (DM) is a noncommunicable disease causing 1.5 million deaths annually in 2012. Its global prevalence is growing dramatically, projecting to 10.4% of the adult population in 2040. Almost 75% ... -
Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H+/K+ATPase Beta Subunit Knockout Mice
Aasarød, Kristin Matre; Waldum, Helge; Stunes, Astrid Kamilla; Sandvik, Arne Kristian; Flatberg, Arnar; Mjønes, Patricia; Syversen, Unni; Bakke, Ingunn; Fossmark, Reidar (Journal article; Peer reviewed, 2020)Proton pump inhibitor use is associated with an increased risk of gastric cancer, which may be mediated by hypergastrinemia. Spasmolytic polypeptide-expression metaplasia (SPEM) has been proposed as a precursor of gastric ... -
High prevalence of dyslipidemia among women in a rural district in Nepal – a population-based cross-sectional study
Randby, Emma; Nordrik, Hanna (Master thesis, 2023)Sammendrag Prevalensen av dyslipidemi øker i hele Sør-Asia. Ifølge kriteriene til NCEP ATP III er dyslipidemi definert som å ha en eller flere av de følgende lipidverdiene i serum: Total-kolesterol (TC) > 5.18 mmol/L, ...