Browsing NTNU Open by Author "Sun, Chen"
Now showing items 1-3 of 3
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Meta-analysis of the human leukocyte antigen-G (HLA-G) 14bp insertion/deletion polymorphism as a risk factor for preeclampsia
Pabalan, Noel; Jarjanazi, H; Sun, Chen; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2015)The non-classical major histocompatibility complex, human leukocyte antigen (HLA)-G, plays an important role in pregnancy. HLA-G mediates proper interaction between maternal immune cells and fetal trophoblasts invading the ... -
Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts
Stødle, Guro; Silva, Gabriela; Tangerås, Line Haugstad; Gierman, Lobke; Nervik, Ingunn; Dahlberg, Unn; Sun, Chen; Aune, Marie Hjelmseth; Thomsen, Liv Cecilie Vestrheim; Bjørge, Line; Iversen, Ann-Charlotte (Journal article; Peer reviewed, 2018)Pre‐eclampsia is associated with increased levels of cholesterol and uric acid and an inflamed placenta expressing danger‐sensing pattern recognition receptors (PRRs). Crystalline cholesterol and uric acid activate the PRR ... -
Refined phenotyping identifies links between preeclampsia and related diseases in a Norwegian preeclampsia family cohort
Thomsen, Liv Cecilie Vestrheim; Melton, Philip E.; Tollaksen, Kjersti; Lyslo, Ingvill; Roten, Linda Tømmerdal; Odland, Maria Lisa; Strand, Kristin Melheim; Nygård, Ottar; Sun, Chen; Iversen, Ann-Charlotte; Austgulen, Rigmor; Moses, Eric; Bjørge, Line (Peer reviewed, 2015)Objective: Preeclampsia is a complex genetic disease of pregnancy with a heterogenous presentation, unknown cause and potential severe outcomes for both mother and child. Preeclamptic women have increased risk for ...