Browsing NTNU Open by Author "Storrø, Ola"
Now showing items 1-20 of 21
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A primary health-care intervention on pre- and postnatal risk factor behavior to prevent childhood allergy. The Prevention of Allergy among Children in Trondheim (PACT) study
Storrø, Ola; Øien, Torbjørn; Dotterud, Christian; Jenssen, Jon Andreas; Johnsen, Roar (Journal article; Peer reviewed, 2010)Background: This study aimed to evaluate the impact of a primary prevention intervention program on risk behavior for allergic diseases among children up to 2 years of age. The setting was in ordinary pre- and postnatal primary ... -
Atopic dermatitis prevention in children following maternal probiotic supplementation does not appear to be mediated by breast milk TSLP or TGF-β.
Simpson, Melanie Rae; Rø, Anne Dorthea; Grimstad, Øystein; Johnsen, Roar; Storrø, Ola; Øien, Torbjørn (Journal article; Peer reviewed, 2016)Background: The Probiotics in Prevention of Allergy among Children in Trondheim (ProPACT) study, a randomised, placebo controlled trial, demonstrated that maternal supplementation with probiotic milk reduced the incidence ... -
Breastfeeding associated microbiota in human milk following supplementation with Lactobacillus rhamnosus GG, Lactobacillus acidophilus La-5 and Bifidobacterium animalis subspecies lactis Bb-12
Simpson, Melanie Rae; Avershina, Ekaterina; Storrø, Ola; Johnsen, Roar; Rudi, Knut; Øien, Torbjørn (Journal article; Peer reviewed, 2017)Breastfeeding is one of the major factors affecting the early development of the infant gut microbiota, and weaning is associated with a shift in the gut microbiota toward a more adult composition. Through breastfeeding, ... -
The commensal infant gut meta-mobilome as a potential reservoir for persistent multidrug resistance integrons
Ravi, Anuradha; Avershina, Ekaterina; Foley, Steven L.; Ludvigsen, Jane; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; McCartney, Anne; L'Abee-Lund, Trine Marie; Rudi, Knut (Peer reviewed; Journal article, 2015)Despite the accumulating knowledge on the development and establishment of the gut microbiota, its role as a reservoir for multidrug resistance is not well understood. This study investigated the prevalence and persistence ... -
Culture dependent and independent analyses suggest a low level of sharing of endospore-forming species between mothers and their children
Avershina, Ekaterina; Larsen, Marte Gro; Aspholm, Marina Elisabeth; Lindbäck, Toril; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Rudi, Knut (Peer reviewed; Journal article, 2020)Spore forming bacteria comprise a large part of the human gut microbiota. However, study of the endospores in gut microbiota is limited due to difficulties of culturing and numerous unknown germination factors. In this ... -
Diversity of vaginal microbiota increases by the time of labor onset
Avershina, Ekaterina; Slangsvold, Silje; Simpson, Melanie Rae; Storrø, Ola; Johnsen, Roar; Øien, Torbjørn; Rudi, Knut (Journal article; Peer reviewed, 2017)Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed ... -
Early eczema and the risk of childhood asthma: a prospective, population-based study
Saunes, Marit; Øien, Torbjørn; Dotterud, Christian Kvikne; Romundstad, Pål Richard; Storrø, Ola; Holmen, Turid Lingaas; Johnsen, Roar (Journal article; Peer reviewed, 2012)Background Severe eczema in young children is associated with an increased risk of developing asthma and rhino-conjunctivitis. In the general population, however, most cases of eczema are mild to moderate. In an unselected ... -
Family eczema-history in 2-year olds with eczema; a prospective, population-based study. The PACT-study, Norway
Saunes, Marit; Øien, Torbjørn; Storrø, Ola; Johnsen, Roar (Journal article; Peer reviewed, 2011)Background: A maternal line of inheritance regarding eczema has been described in several studies, whereas others find associations to both a maternal as well as a paternal line of inheritance. When studying family ... -
Fish Consumption at One Year of Age Reduces the Risk of Eczema, Asthma and Wheeze at Six Years of Age
Øien, Torbjørn; Schjelvaag, Astrid; Storrø, Ola; Johnsen, Roar; Simpson, Melanie Rae (Journal article; Peer reviewed, 2019)We present a novel liquid array diagnostics (LAD) method, which enables rapid and inexpensive detection of microbial markers in a single-tube multiplex reaction. We evaluated LAD both on pure cultures, and on infant gut ... -
Human Breast Milk miRNA, Maternal Probiotic Supplementation and Atopic Dermatitis in Offspring
Simpson, Melanie Rae; Brede, Gaute; Johansen, Jostein; Johnsen, Roar; Storrø, Ola; Sætrom, Pål; Øien, Torbjørn (Peer reviewed; Journal article, 2015)Background: Perinatal probiotic ingestion has been shown to prevent atopic dermatitis (AD) in infancy in a number of randomised trials. The Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT) trial ... -
Liquid array diagnostics: A novel method for rapid detection of microbial communities in single-tube multiplex reactions
Hiseni, Pranvera; Wilson, Robert Charles; Storrø, Ola; Johnsen, Roar; Øien, Torbjørn; Rudi, Knut (Journal article; Peer reviewed, 2019)We present a novel liquid array diagnostics (LAD) method, which enables rapid and inexpensive detection of microbial markers in a single-tube multiplex reaction. We evaluated LAD both on pure cultures, and on infant gut ... -
Low maternal microbiota sharing across gut, breast milk and vagina, as revealed by 16s rRNA gene and reduced metagenomic sequencing
Avershina, Ekaterina; Angell, Inga Leena; Simpson, Melanie Rae; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Rudi, Knut (Journal article; Peer reviewed, 2018)The maternal microbiota plays an important role in infant gut colonization. In this work we have investigated which bacterial species are shared across the breast milk, vaginal and stool microbiotas of 109 women shortly ... -
Major faecal microbiota shifts in composition and diversity with age in a geographically restricted cohort of mothers and their children
Avershina, Ekaterina; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Pope, Phil; Rudi, Knut (Journal article; Peer reviewed, 2014)Despite the importance, the diversity of the human infant gut microbiota still remains poorly characterized at the regional scale. Here, we investigated the faecal microbiota diversity in a large 16S rRNA gene data set ... -
Modification of adjuvant risk factor behaviours for allergic disease and association between early gut microbiota and atopic sensitization and eczema.: Early life events defining the future health of our children[1] The prevention of Allergy among Children in Trondheim (PACT) study
Storrø, Ola (Doktoravhandlinger ved NTNU, 1503-8181; 2011:311, Doctoral thesis, 2011) -
Perinatal probiotic supplementation in the prevention of allergy related disease: 6 year follow up of a randomised controlled trial
Simpson, Melanie Rae; Dotterud, Christian Kvikne; Storrø, Ola; Johnsen, Roar; Øien, Torbjørn (Journal article; Peer reviewed, 2015)Background: Perinatal probiotics supplementation has been shown to be effective in the primary prevention of atopic dermatitis (AD) in early childhood, although the long term effects of probiotics on AD and other allergic ... -
Potential association of vacuum cleaning frequency with an altered gut microbiota in pregnant women and their 2-year-old children
Avershina, E.; Ravi, Anuradha; Storrø, Ola; Øien, Torbjørn; Johnsen, Roar; Rudi, Knut (Journal article; Peer reviewed, 2015)Background: Westernized lifestyle and hygienic behavior have contributed to dramatic changes in the human-associated microbiota. This particularly relates to indoor activities such as house cleaning. We therefore investigated ... -
Preventing atopic dermatitis with probiotic supplementation - the role of selected breast milk components: The Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT) study
Simpson, Melanie Rae (Doctoral theses at NTNU;2018:116, Doctoral thesis, 2018)Probiotika i forebygging av atopisk eksem - rollen til utvalgte morsmelk faktorer Probiotikatilskudd i siste del av svangerskapet og de første levemåneder forebygger utvikling av atopisk dermatitt hos barn. Denne effekten ... -
Primary prevention of atopic diseases: The Prevention of Allergy among Children in Trondheim (PACT) study
Dotterud, Christian Kvikne (Doctoral thesis at NTNU;2016:151, Doctoral thesis, 2016)There has been a substantial increase in asthma, atopic dermatitis and allergic rhinoconjunctivitis in countries with a “western lifestyle” since the 1960s. Today the prevalence of these atopic diseases is high. Both a ... -
Reduced Th22 cell proportion and prevention of atopic dermatitis in infants following maternal probiotic supplementation
Rø, Anne Dorthea; Simpson, Melanie Rae; Rø, Torstein Baade; Storrø, Ola; Johnsen, Roar; Videm, Vibeke; Øien, Torbjørn (Journal article; Peer reviewed, 2017)Background In the randomized, controlled study Probiotics in the Prevention of Allergy among Children in Trondheim (ProPACT), maternal probiotic supplementation reduced the incidence of atopic dermatitis (AD) in the ... -
The impact of a minimal smoking cessation intervention for pregnant women and their partners on perinatal smoking behaviour in primary health care: A real-life controlled study
Øien, Torbjørn; Storrø, Ola; Jenssen, Jon Andreas; Johnsen, Roar (Journal article; Peer reviewed, 2008)Background: There is a demand for strategies to promote smoking cessation in high-risk populations like smoking pregnant women and their partners. The objectives of this study were to investigate parental smoking behaviour ...