• Angiogenesis and radiological tumor growth in patients with glioblastoma 

      Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Granli, Unn Sophie; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Journal article; Peer reviewed, 2018)
      Background The preoperative growth of human glioblastomas (GBMs) has been shown to vary among patients. In animal studies, angiogenesis has been linked to hypoxia and faster growth of GBM, however, its relation to the ...
    • Glioblastoma Segmentation: Comparison of Three Different Software Packages 

      Fyllingen, Even Hovig; Stensjøen, Anne Line; Berntsen, Erik Magnus; Reinertsen, Ingerid; Solheim, Ole (Journal article; Peer reviewed, 2016)
      To facilitate a more widespread use of volumetric tumor segmentation in clinical studies, there is an urgent need for reliable, user-friendly segmentation software. The aim of this study was therefore to compare three ...
    • Intra-observer Variability in Segmentation of Glioblastomas 

      Stensjøen, Anne Line (Master thesis, 2014)
      Background: Glioblastomas are primary malignant brain tumors with poor prognosis. In study settings where tumor growth and treatment responses are assessed, tumor volumes are measured. To obtain valid volume measures ...
    • MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas 

      Mikkelsen, Vilde Elisabeth; Hong, Yan Dai; Stensjøen, Anne Line; Berntsen, Erik Magnus; Salvesen, Øyvind; Solheim, Ole; Torp, Sverre Helge (Peer reviewed; Journal article, 2020)
      O6-methylguanine DNA methyltransferase (MGMT) promoter methylation is an important favorable predictive marker in patients with glioblastoma (GBM). We hypothesized that MGMT status could be a surrogate marker of pretreatment ...
    • Microglia and macrophages in human glioblastomas: A morphological and immunohistochemical study 

      Kvisten, Magnus; Mikkelsen, Vilde Elisabeth; Stensjøen, Anne Line; Solheim, Ole; van der Want, Johannes Jacobus Leendert; Torp, Sverre Helge (Journal article; Peer reviewed, 2019)
      Glioblastomas (GBMs), a type of highly malignant brain tumour, contain various macrophages/microglia that are known as tumour‑associated macrophages (TAMs). These TAMs have various roles in tumour biology. Histopathological ...
    • The Direction of Tumour Growth in Glioblastoma Patients 

      Esmaeili, Morteza; Stensjøen, Anne Line; Berntsen, Erik Magnus; Solheim, Ole; Reinertsen, Ingerid (Journal article; Peer reviewed, 2018)
      Generating MR-derived growth pattern models for glioblastoma multiforme (GBM) has been an attractive approach in neuro-oncology, suggesting a distinct pattern of lesion spread with a tendency in growing along the white ...