Blar i NTNU Open på forfatter "Sommerfelt, Randi Magnus"
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Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes
Sommerfelt, Randi Magnus; Feuerherm, Astrid Jullumstrø; Skuland, Trine; Johansen, Berit (Journal article; Peer reviewed, 2015)Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis leading to destruction of cartilage and bone. PLA2 enzymes are key players in inflammation regulating the release of unsaturated fatty ... -
Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes
Sommerfelt, Randi Magnus; Feuerherm, Astrid Jullumstrø; Jones, Kymry; Johansen, Berit (Journal article; Peer reviewed, 2013)Introduction: Rheumatoid arthritis (RA) is an inflammatory disease of the joint characterized by chronic synovitis causing pain, swelling and loss of function due to destruction of cartilage and bone. The complex series ... -
Molecular mechanisms of inflammation – a central role for cytosolic phospholipase A2
Sommerfelt, Randi Magnus (Doktoravhandlinger ved NTNU, 1503-8181; 2014:189, Doctoral thesis, 2014)cPLA2α – a central regulator of inflammation Bioactive lipids are central in regulating the inflammatory process and imbalance in lipid mediator signaling contributes to progression of pathological conditions such as ...