Blar i NTNU Open på forfatter "Solheim, Tora Skeidsvoll"
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A cross-sectional study examining the prevalence of cachexia and areas of unmet need in patients with cancer
Vagnildhaug, Ola Magne; Balstad, Trude Rakel; Almberg, Sigrun Saur; Brunelli, Cinzia; Knudsen, Anne Kari; Kaasa, Stein; Thronæs, Morten; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2017)Purpose The semantics of defining cancer cachexia over the last decade has resulted in uncertainty as to the prevalence. This has further hindered the recognition and subsequent treatment of this condition. Following the ... -
A prospective study examining cachexia predictors in patients with incurable cancer
Vagnildhaug, Ola Magne; Brunelli, Cinzia; Hjermstad, Marianne Jensen; Strasser, Florian; Baracos, Vickie; Wilcock, Andrew; Nabal, María; Kaasa, Stein; Laird, Barry J; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)Background Early intervention against cachexia necessitates a predictive model. The aims of this study were to identify predictors of cachexia development and to create and evaluate accuracy of a predictive model based ... -
A randomized phase II feasibility trial of a multimodal intervention for the management of cachexia in lung and pancreatic cancer
Solheim, Tora Skeidsvoll; Laird, Barry J; Balstad, Trude Rakel; Stene, Guro Birgitte; Bye, Asta; Johns, Neil; Pettersen, Caroline Hild Hakvåg; Fallon, Marie; Fayers, Peter; Fearon, Kenneth; Kaasa, Stein (Journal article; Peer reviewed, 2017)Background: Cancer cachexia is a syndrome of weight loss (including muscle and fat), anorexia, and decreased physical function. It has been suggested that the optimal treatment for cachexia should be a multimodal intervention. ... -
Appetite loss in patients with cancer treated at an Acute Palliative Care Unit
Ulevåg, Ragnhild; Helgesen, Elisabeth Hagen (Master thesis, 2024)Bakgrunn: Appetittap er et vanlig symptom hos pasienter med avansert kreftsykdom og har en negativ innvirkning på livskvaliteten til pasienten. På tross av dette er forståelsen av assosierte faktorer til appetittap begrenset. ... -
Appetite loss in patients with cancer treated at an Acute Palliative Care Unit
Helgesen, Elisabeth Hagen; Ulevåg, Ragnhild (Master thesis, 2024)Bakgrunn: Appetittap er et vanlig symptom hos pasienter med avansert kreftsykdom og har en negativ innvirkning på livskvaliteten til pasienten. På tross av dette er forståelsen av assosierte faktorer til appetittap begrenset. ... -
Associations between hematologic toxicity and health-related quality of life during first-line chemotherapy in advanced non-small-cell lung cancer: a pooled analysis of two randomized trials
Kristensen, Are Korsnes; Solheim, Tora Skeidsvoll; Fløtten, Øystein; Grønberg, Bjørn Henning (Journal article; Peer reviewed, 2018)Background: Many patients experience toxicity from chemotherapy that may negatively impact their health-related quality of life (HRQoL), but side effects often go undetected by health care personnel. Our aim was to investigate ... -
Breakthrough and Episodic Cancer Pain from a Palliative Care Perspective
Løhre, Erik Torbjørn; Jakobsen, Gunnhild; Solheim, Tora Skeidsvoll; Klepstad, Pål; Thronæs, Morten (Peer reviewed; Journal article, 2023)Cancer pain intensity (PI) fluctuates, but the relationship between pain flares and background pain with respect to pain management is not settled. We studied how flare and background PIs corresponded with treatment results ... -
Cancer Cachexia: Classification, Pathophysiology and Treatment
Solheim, Tora Skeidsvoll (Doktoravhandlinger ved NTNU, 1503-8181; 2014:49, Doctoral thesis, 2014)Cachexia is a very common condition in patients with cancer and it has detrimental effects on both mortality and morbidity. Cachexia is characterized by progressive unintentional loss of muscle mass, with or without loss ... -
Cancer cachexia: Rationale for the MENAC (Multimodal - Exercise, Nutrition and Anti-inflammatory medication for Cachexia) trial
Solheim, Tora Skeidsvoll; Laird, Barry J. A.; Balstad, Trude Rakel; Bye, Asta; Stene, Guro Birgitte; Baracos, Vickie; Strasser, Florian; Griffiths, Gareth; Maddocks, Matthew; Fallon, Marie; Kaasa, Stein; Fearon, Kenneth (Journal article; Peer reviewed, 2018)Cancer cachexia is a multifactorial syndrome characterised by an ongoing loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support alone. Cachexia has a high prevalence in cancer and a ... -
Combining optimal nutrition and exercise in a multimodal approach for patients with active cancer and risk for losing weight: Rationale and practical approach
Solheim, Tora Skeidsvoll; Vagnildhaug, Ola Magne; Laird, Barry J; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)Weight loss and functional decline is a common and detrimental consequence of cancer. The interventions that are offered to patients with weight loss and functional decline often seem haphazard and varying from center to ... -
Deterioration in Muscle Mass and Physical Function Differs According to Weight loss History in Cancer Cachexia
Stene, Guro Birgitte; Balstad, Trude Rakel; Leer, Anne Silja Mäkitalo; Bye, Asta; Kaasa, Stein; Fallon, Marie T.; Laird, Barry J; Maddocks, Matthew; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2019)Background: Muscle mass and physical function (PF) are common co-primary endpoints in cancer cachexia trials, but there is a lack of data on how these outcomes interact over time. The aim of this secondary analysis of data ... -
Development of the EORTC QLQ-CAX24, A Questionnaire for Cancer Patients With Cachexia
Wheelwright, Sally J.; Hopkinson, Jane B.; Darlington, Anne-Sophie; Fitzsimmons, Deborah F.; Fayers, Peter; Balstad, Trude Rakel; Bredart, Anne; Hammerlid, Eva; Kaasa, Stein; Nicolatou-Galitis, Ourania; Pinto, Monica; Schmidt, Heike; Solheim, Tora Skeidsvoll; Strasser, Florian; Tomaszewska, IM; Johnson, Colin D. (Journal article; Peer reviewed, 2017)Context Cachexia is commonly found in cancer patients and has profound consequences; yet there is only one questionnaire that examines the patient's perspective. Objective To report a rigorously developed module for ... -
Dietary treatment of weight loss in patients with advanced cancer and cachexia: A systematic literature review
Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Strasser, Florian; Kaasa, Stein; Bye, Asta (Journal article; Peer reviewed, 2014)Purpose: A systematical literature review evaluating the effect of dietary counseling in treating weight loss and improving energy intake in patients with advanced cancer with different stages of cachexia. Principal ... -
Disulfiram repurposing combined with nutritional copper supplement as add-on to chemotherapy in recurrent glioblastoma (DIRECT): Study protocol for a randomized controlled trial
Jakola, Asgeir S.; Werlenius, Katja; Mudaisi, Munila; Hylin, Sofia; Kinhult, Sara; bartek, Jiri Jr.; Salvesen, Øyvind; Carlsen, Sven Magnus; Strandeus, Michael; Lindskog, Magnus; Lofgren, David; Rydenhaug, Bertil; Carstam, Louise; Gulati, Sasha; Solheim, Ole; Bartek, Jiri; Solheim, Tora Skeidsvoll (Journal article; Peer reviewed, 2018)Background: Disulfiram (DSF) is a well-tolerated, inexpensive, generic drug that has been in use to treat alcoholism since the 1950s. There is now independent preclinical data that supports DSF as an anticancer agent, and ... -
Effects of current parenteral nutrition treatment on health-related quality of life, physical function, nutritional status, survival and adverse events exclusively in patients with advanced cancer: A systematic literature review
Tobberup, Randi; Thoresen, Lene; Falkmer, Ursula; Yilmaz, Mette K.; Solheim, Tora Skeidsvoll; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)Background: The aim was to evaluate the effects of current parenteral nutrition (PN) treatment on clinical outcomes in patients with advanced cancer. Methods: This review was conducted according to the PRISMA guidelines ... -
Endpoints in clinical trials in cancer cachexia: where to start?
Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Laird, Barry J. A. (Journal article; Peer reviewed, 2018)Purpose of review The lack of agreement and knowledge of optimal endpoints in cachexia trials have impeded progress in finding interventions counteracting the devastating effects cancer cachexia has on morbidity and ... -
ESPEN guidelines on nutrition in cancer patients
Arends, Jann; Bachmann, Peter; Baracos, Vickie; Barthelemy, N; Bertz, H; Bozzetti, Frederico; Fearon, KC; Hütterer, E; Isenring, E; Kaasa, Stein; Krznaric, Z; Laird, Barry J.; Larsson, M; Laviano, A; Mühlebach, S; Muscaritoli, Maurizio; Oldervoll, Line Merethe; Ravasco, Paula; Solheim, Tora Skeidsvoll; Strasser, Florian; de van der Schueren, Marian; Preiser, JC (Journal article; Peer reviewed, 2017)Cancers are among the leading causes of morbidity and mortality worldwide, and the number of new cases is expected to rise significantly over the next decades. At the same time, all types of cancer treatment, such as ... -
Exercise and nutrition interventions in patients with head and neck cancer during curative treatment: A systematic review and meta-analysis
Bye, Asta; Sandmæl, Jon Arne; Stene, Guro Birgitte; Thorsen, Lene; Balstad, Trude Rakel; Solheim, Tora Skeidsvoll; Pripp, Are Hugo; Oldervoll, Line Merethe (Peer reviewed; Journal article, 2020)The aim of this meta-analysis was to examine the effects of nutritional and physical exercise interventions and interventions combining these interventions during radiotherapy treatment for patients with head and neck ... -
Food intake by Patient-Generated Subjective Global Assessment (PG-SGA) corresponds to energy and protein intake as well as weight change in patients with advanced cancer
Bye, Asta; Meli, Kari; Solheim, Tora Skeidsvoll; Laird, Barry J; Kaasa, Stein; Stene, Guro Birgitte; Balstad, Trude Rakel (Journal article; Peer reviewed, 2019)Background & aims The aim of this study was to test how well the Patient-Generated Subjective Global Assessment (PG-SGA) question about food intake correlates with a well-established measurement of food intake. Furthermore, ... -
Healthcare professionals’ support to primary family carers of patients with advanced cancer
Røen, Ingebrigt (Doctoral theses at NTNU;2022:317, Doctoral thesis, 2022)