Browsing NTNU Open by Author "Smits, Anja"

Now showing items 1-11 of 11

    • Depression and ability to work after vestibular schwannoma surgery: a nationwide registry-based matched cohort study on antidepressants, sedatives, and sick leave 

      Thurin, Erik; Förander, Petter; bartek, Jiri Jr.; Gulati, Sasha; Rydén, Isabelle; Smits, Anja; Hesselager, Göran; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background In patients with vestibular schwannomas (VS), tumor control is often achieved, and life expectancy is relatively good. The main risks of surgical treatment are hearing loss and facial nerve function. The occurrence ...

    • Determinants for Effective ALECSAT Immunotherapy Treatment on Autologous Patient-Derived Glioblastoma Stem Cells 

      Wenger, Anna; Werlenius, Katja; Hallner, Alexander; Fredrik Bergh, Thoren; Farahmand, Dan; Tisell, Magnus; Smits, Anja; Rydenhag, Bertil; Jakola, Asgeir Store; Caren, Helena (Peer reviewed; Journal article, 2018)
      Glioblastoma (GBM) is the most aggressive primary brain tumor with a median survival of less than 15 months, emphasizing the need for better treatments. Immunotherapy as a treatment for improving or aiding the patient’s ...

    • DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas 

      Ferreyra Vega, Sandra; Olsson Bontell, Thomas; Corell, Alba; Smits, Anja; Jakola, Asgeir Store; Carén, Helena (Peer reviewed; Journal article, 2021)
      Background - DNA methylation profiling has facilitated and improved the classification of a wide variety of tumors of the central nervous system. In this study, we investigated the potential utility of DNA methylation ...

    • Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study 

      Thurin, Erik; Rydén, Isabelle; Skoglund, Thomas; Smits, Anja; Gulati, Sasha; Hesselager, Göran; Bartek, Jiri Jr.; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background: Meningioma is the most common primary intracranial tumor and surgery is the main treatment modality. As death from lack of tumor control is rare, other outcome measures like anxiety, depression and post-operative ...

    • Long-term follow up of patients with WHO grade 2 oligodendroglioma 

      Carstam, Louise; Latini, Francesco; Solheim, Ole Skeidsvoll; Bartek, Jiri; Pedersen, Lars Kjelsberg; Zetterling, Maria; Beniaminov, Stanislav; Sjåvik, Kristin; Ryttlefors, Mats; Jensdottir, Margret; Rydenhag, Bertil; Smits, Anja; Jakola, Asgeir Store (Peer reviewed; Journal article, 2023)
      Purpose Since the introduction of the molecular definition of oligodendrogliomas based on isocitrate dehydrogenase (IDH)-status and the 1p19q-codeletion, it has become increasingly evident how this glioma entity differs ...

    • Prognostic markers for survival in patients with oligodendroglial tumors; a single-institution review of 214 cases 

      Zetterling, Maria; Berhane, Luwane; Alafuzoff, Irina; Jakola, Asgeir Store; Smits, Anja (Peer reviewed; Journal article, 2017)
      Background: In the 2016 WHO classification, the diagnosis of oligodendroglioma has been restricted to IDH mutated, 1p19q codeleted tumors (IDHmut-codel). IDHmut oligoastrocytoma is now classified either as oligodendroglioma ...

    • Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study 

      Rydén, Isabelle; Thurin, Erik; Carstam, Louise; Smits, Anja; Gulati, Sasha; Henriksson, Roger; Salvesen, Øyvind; Jakola, Asgeir Store (Journal article; Peer reviewed, 2021)
      Background: Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease. While epilepsy is well-described in patients ...

    • Return to work following meningioma surgery: a Swedish nationwide registry-based matched cohort study 

      Thurin, Erik; Corell, Alba; Gulati, Sasha; Smits, Anja; Henriksson, Roger; Bartek, Jiri Jr.; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2020)
      Background Meningioma is the most common primary intracranial tumor. It is usually slow growing and benign, and surgery is the main treatment modality. There are limited data on return to work following meningioma ...

    • Socioeconomic factors affect treatment delivery for patients with low grade glioma: a Swedish population-based study 

      Carstam, Louise; Rydén, Isabelle; Gulati, Sasha; Rydenhag, Bertil; Henriksson, Roger; Salvesen, Øyvind; Smits, Anja; Jakola, Asgeir S (Peer reviewed; Journal article, 2019)
      Background Despite aspirations to achieve equality in healthcare we know that socioeconomic differences exist and may affect treatment and patient outcome, also in serious diseases such as cancer. We investigated ...

    • Stemness and clinical features in relation to the subventricular zone in diffuse lower-grade glioma: An exploratory study 

      Corell, Alba; Gómez Vecchio, Tomás; Ferreyra Vega, Sandra; Dénes, Anna; Neimantaite, Alice; Hagerius, Alexander; Barchéus, Hanna; Solheim, Ole; Lindskog, Cecilia; Bontell, Thomas Olsson; Carén, Helena; Jakola, Asgeir Store; Smits, Anja (Peer reviewed; Journal article, 2022)
      Background The subventricular zone (SVZ) of the human brain is a site of adult stem cell proliferation and a microenvironment for neural stem cells (NSCs). It has been suggested that NSCs in the SVZ are potential cells ...

    • Variations in the management of diffuse low-grade gliomas - A Scandinavian multicenter study 

      Munkvold, Bodil Karoline Ravn; Solheim, Ole; Bartek, Jiri; Corell, Alba; De Dios, Eddie; Gulati, Sasha; Helseth, Eirik; Holmgren, Klas; Jensdottir, Margret; Lundborg, Mina; Mireles, Eduardo Erasmo Mendoza; Mahesparan, Rupavathana; Tveiten, Øystein Vesterli; Milos, Peter; Redebrandt, Henrietta Nittby; Pedersen, Lars Kjelsberg; Ramm-Pettersen, Jon-Terje; Sjöberg, Rickard L; Sjögren, Björn; Sjåvik, Kristin; Smits, Anja; Tomasevic, Gregor; Vecchio, Tomás Gómez; Vik-Mo, Einar O.; Zetterling, Maria; Salvesen, Øyvind; Jakola, Asgeir Store (Peer reviewed; Journal article, 2021)
      Background Early extensive surgery is a cornerstone in treatment of diffuse low-grade gliomas (DLGGs), and an additional survival benefit has been demonstrated from early radiochemotherapy in selected “high-risk” patients. ...