Blar i NTNU Open på forfatter "Smith, Oliver"

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    • Ancient microRNA profiles of 14,300-yr-old canid samples confirm taxonomic origin and provide glimpses into tissue-specific gene regulation from the Pleistocene 

      Fromm, Bastian; Tarbier, Marcel; Smith, Oliver; Mármol-Sánchez, Emilio; Dalén, Love; Gilbert, Marcus Thomas Pius; Friedländer, Marc R. (Peer reviewed; Journal article, 2021)
      DNA sequencing is the current key technology for historic or ancient biological samples and has led to many exciting discoveries in the field of paleogenomics. However, functional insights into tissue identity, cellular ...

    • Ancient RNA from Late Pleistocene permafrost and historical canids shows tissue-specific transcriptome survival 

      Smith, Oliver; Dunshea, Glenn; Sinding, Mikkel-Holger; Fedorov, Sergey; Germonpre, Mietje; Bocherens, Hervé; Gilbert, Marcus Thomas Pius (Journal article; Peer reviewed, 2019)
      While sequencing ancient DNA (aDNA) from archaeological material is now commonplace, very few attempts to sequence ancient transcriptomes have been made, even from typically stable deposition environments such as permafrost. ...

    • The extinct Sicilian wolf shows a complex history of isolation and admixture with ancient dogs 

      Ciucani, Marta Maria; Ramos-Madrigal, Jazmín; Hernández-Alonso, Germán; Carmagnini, Alberto; Aninta, Sabhrina Gita; Sun, Xin; Scharff-Olsen, Camilla Hjorth; Lanigan, Liam Thomas; Fracasso, Ilaria; Clausen, Cecilie G.; Aspi, Jouni; Kojola, Ilpo; Baltrūnaitė, Laima; Balčiauskas, Linas; Moore, Jane; Åkesson, Mikael; Saarma, Urmas; Hindrikson, Maris; Hulva, Pavel; Bolfíková, Barbora Černá; Nowak, Carsten; Godinho, Raquel; Smith, Steve; Paule, Ladislav; Nowak, Sabina; Mysłajek, Robert W.; Lo Brutto, Sabrina; Ciucci, Paolo; Boitani, Luigi; Vernesi, Cristiano; Stenøien, Hans Kristen; Smith, Oliver; Frantz, Laurent; Rossi, Lorenzo; Angelici, Francesco Maria; Cilli, Elisabetta; Sinding, Mikkel Holger Strander; Gilbert, Marcus Thomas Pius; Gopalakrishnan, Shyam (Peer reviewed; Journal article, 2023)
      The Sicilian wolf remained isolated in Sicily from the end of the Pleistocene until its extermination in the 1930s–1960s. Given its long-term isolation on the island and distinctive morphology, the genetic origin of the ...

    • Probing the genomic limits of de-extinction in the Christmas Island rat 

      Lin, Jianqing; Duchêne, David; Carøe, Christian; Smith, Oliver; Ciucani, Marta Maria; Niemann, Jonas; Richmond, Douglas; Greenwood, Alex D.; MacPhee, Ross; Zhang, Guojie; Gopalakrishnan, Shyam; Gilbert, Marcus Thomas Pius (Peer reviewed; Journal article, 2022)
      Three principal methods are under discussion as possible pathways to “true” de-extinction; i.e., back-breeding, cloning, and genetic engineering.1,2 Of these, while the latter approach is most likely to apply to the largest ...