Blar i NTNU Open på forfatter "Smith, Godfrey L"
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Atrial Myocyte Function and Ca2+ Handling Is Associated with Inborn Aerobic Capacity
Johnsen, Anne Berit; Rolim, Natale Pinheiro Lage; Stølen, Tomas; Alves, Marcia; Sousa, Mirta; Slupphaug, Geir; Britton, Steven L; Koch, Lauren G; Smith, Godfrey L; Wisløff, Ulrik; Høydal, Morten Andre (Peer reviewed; Journal article, 2013-10-16)Background: Although high aerobic capacity is associated with effective cardiac function, the effect of aerobic capacity on atrial function, especially in terms of cellular mechanisms, is not known. We aimed to investigate ... -
Characterization of Electrical Activity in Post-myocardial Infarction Scar Tissue in Rat Hearts Using Multiphoton Microscopy
Ghouri, Iffath A; Kelly, Allan; Salerno, Simona; Garten, Karin; Stølen, Tomas; Smith, Godfrey L (Journal article; Peer reviewed, 2018)Background: The origin of electrical behavior in post-myocardial infarction scar tissue is still under debate. This study aims to examine the extent and nature of the residual electrical activity within a stabilized ... -
Human cardiomyocyte calcium handling and transverse tubules in mid-stage of post-myocardial-infarction heart failure
Høydal, Morten; Karevold, Asbjørn; Garstad, Idar Kirkeby; Wiseth, Rune; Haaverstad, Rune; Stølen, Tomas; Contu, Riccardo; Condorelli, Gianluigi; Ellingsen, Øyvind; Smith, Godfrey L; Kemi, Ole J; Wisløff, Ulrik (Journal article; Peer reviewed, 2018)Aims Cellular processes in the heart rely mainly on studies from experimental animal models or explanted hearts from patients with terminal end‐stage heart failure (HF). To address this limitation, we provide data on ... -
Prediction of Ventricular Arrhythmias by QRS/QTc - Ratio in Citalopram or Escitalopram Intoxication
Dietrichs, Erik Sveberg; Smith, Godfrey L (Peer reviewed; Journal article, 2022)Background: The U.S. Food and Drug Administration (FDA) has stated that citalopram and escitalopram should not be used at daily doses above 40 mg/20 mg due to risk for development of fatal ventricular arrhythmias like ... -
Resistance to ventricular fibrillation predicted by the QRS/QTc - ratio in an intact rat model of hypothermia/rewarming
Dietrichs, Erik Sveberg; Selli, Anders Lund; Kondratiev, Timofei; McGlynn, Karen; Smith, Godfrey L; Tveita, Torkjel (Peer reviewed; Journal article, 2021)Accidental hypothermia is associated with increased risk for arrhythmias. QRS/QTc is proposed as an ECG-marker, where decreasing values predict hypothermia-induced ventricular arrhythmias. If reliable it should also predict ...