Browsing NTNU Open by Author "Slagsvold, Katrine Hordnes"
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5 Years of Surgical Aortic Valve Replacement at St. Olavs Hospital – Assessment of Echocardiographic Data, Clinical Outcome and Prevalence of Patient-Prosthesis Mismatch
Eide, Julie Roald; Korpberget, Susanna (Master thesis, 2022)SAMMENDRAG Mål: Denne studien tok sikte på å beskrive pasientpopulasjonen som gjennomgikk åpen hjerteoperasjon med bytte av aortaklaff på St. Olavs Hospital, inkludert pasientkarakteristika, risikofaktorer, samt kliniske ... -
Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial
Smenes, Benedikte; Bækkerud, Fredrik Hjulstad; Slagsvold, Katrine Hordnes; Hassel, Erlend; Wohlwend, Martin; Pinho, Maria; Høydal, Morten; Wisløff, Ulrik; Rognmo, Øivind; Wahba, Alexander (Journal article; Peer reviewed, 2018)OBJECTIVES During open-heart surgery, the myocardium experiences ischaemia–reperfusion injury. A single bout of moderate, 30-min exercise induces preconditioning and protects the heart from ischaemia–reperfusion injury ... -
Comparison of left versus right atrial myocardium in patients with sinus rhythm or atrial fibrillation - an assessment of mitochondrial function and microRNA expression.
Slagsvold, Katrine Hordnes; Johnsen, Anne Berit; Rognmo, Øivind; Høydal, Morten; Wisløff, Ulrik; Wahba, Alexander (Journal article; Peer reviewed, 2014)Several of the cellular alterations involved in atrial fibrillation (AF) may be linked to mitochondrial function and altered microRNA (miR) expression. A majority of studies on human myocardium involve right atrial (RA) ... -
Complete embolization of a mechanical aortic valve during trail running - a case report with a lucky ending
Dalen, Håvard; Graven, Torbjørn; Slagsvold, Katrine Hordnes; Krogstad, Lars Erik Berg; Saxhaug, Lars Mølgaard; Tannvik, Tomas Dybos; Holte, Espen; Nordhaug, Dag Ole; Karlsen, Øystein; Thorstensen, Anders; Wahba, Alexander; Winnerkvist, Anders (Peer reviewed; Journal article, 2022)Background Complete embolization of a prosthetic heart valve is extremely rare and dangerous. This case reports a total embolization of a mechanical aortic valve and contributes to the literature regarding the diagnostic ... -
Endokarditt- nye trender i Helse Midt-Norge
Granild, Milja (Master thesis, 2021)Formål Formålet med oppgaven er å evaluere utviklingen i insidens, etiologi, risikofaktorer, diagnostikk, behandling, morbiditet og mortalitet hos pasienter som ble behandlet for infeksiøs endokarditt på St. Olavs hospital ... -
GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia
Marwarha, Gurdeep; Røsand, Øystein; Slagsvold, Katrine Hordnes; Høydal, Morten (Peer reviewed; Journal article, 2022)Apoptotic cell death is a deleterious consequence of hypoxia-induced cellular stress. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxia stress. We have ... -
Infeksiøs endokarditt ved St. Olavs hospital 2010-2020 - Bruk av kardiale bildemodaliteter og karakteristika ved klaffeaffeksjon
de Lanlay, Even (Master thesis, 2021)Infeksiøs endokarditt er en alvorlig tilstand som karakteriseres blant annet av endokardiell bakteriekolonisering og systemisk infeksjon. Sykdommen rammer oftest hjertets klaffer, men kan også føre til mikro- eller septiske ... -
miR-210 Regulates Apoptotic Cell Death during Cellular Hypoxia and Reoxygenation in a Diametrically Opposite Manner
Marwarha, Gurdeep; Røsand, Øystein; Scrimgeour, Nathan Robert; Slagsvold, Katrine Hordnes; Høydal, Morten (Peer reviewed; Journal article, 2021)Apoptotic cell death of cardiomyocytes is a characteristic hallmark of ischemia–reperfusion (I/R) injury. The master hypoxamiR, microRNA-210 (miR-210), is considered the primary driver of the cellular response to hypoxic ... -
Myocardial Physiology in Individuals Undergoing Heart Surgery
Slagsvold, Katrine Hordnes (Doctoral thesis at NTNU;, Doctoral thesis, 2014)Mitochondria are essential organelles in all eukaryote cells. They produce the vast majority of all the energy the heart needs to continuously pump oxygenated blood throughout the body. The myocardium is entirely dependent ... -
NF-κB Transcriptional Activity Indispensably Mediates Hypoxia–Reoxygenation Stress-Induced microRNA-210 Expression
Marwarha, Gurdeep Singh Atamjit; Slagsvold, Katrine Hordnes; Høydal, Morten Andre (Peer reviewed; Journal article, 2023)Ischemia–reperfusion (I-R) injury is a cardinal pathophysiological hallmark of ischemic heart disease (IHD). Despite significant advances in the understanding of what causes I-R injury and hypoxia–reoxygenation (H-R) stress, ...