Blar i NTNU Open på forfatter "Skjaervold, Nils Kristian"
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A pig model of acute right ventricular afterload increase by hypoxic pulmonary vasoconstriction
Knai, Kathrine; Skjaervold, Nils Kristian (Journal article; Peer reviewed, 2017)Background: The aim of this study was to construct a non-invasive model for acute right ventricular afterload increase by hypoxic pulmonary vasoconstriction. Intact animal models are vital to improving our understanding ... -
Blood Glucose Control Using a Novel Continuous Blood Glucose Monitor and Repetitive Intravenous Insulin Boluses: Exploiting Natural Insulin Pulsatility as a Principle for a Future Artificial Pancreas
Skjaervold, Nils Kristian; Østling, Dan; Hjelme, Dag Roar; Spigset, Olav; Lyng, Oddveig; Aadahl, Petter (Journal article; Peer reviewed, 2013)The aim of this study was to construct a glucose regulatory algorithm by employing the natural pulsatile pattern of insulin secretion and the oscillatory pattern of resting blood glucose levels and further to regulate the ... -
Characteristics of circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study
Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Skaug, Thomas Renhult; Nordseth, Trond; Klepstad, Pål; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2022)Background Circulatory failure after out-of-hospital cardiac arrest (OHCA) as part of the postcardiac arrest syndrome (PCAS) is believed to be caused by an initial myocardial depression that later subsides into a superimposed ... -
Circulatory trajectories after out-of-hospital cardiac arrest: a prospective cohort study
Langeland, Halvor; Langeland, Halvor; Bergum, Daniel; Nordseth, Trond; Løberg, Magnus; Skaug, Thomas; Skaug, Thomas Renhult; Bjørnstad, Knut; Bjørnstad, Knut; Gundersen, Ørjan; Skjaervold, Nils Kristian; Klepstad, Pål (Peer reviewed; Journal article, 2021)Background: Circulatory failure frequently occurs after out-of-hospital cardiac arrest (OHCA) and is part of postcardiac arrest syndrome (PCAS). The aim of this study was to investigate circulatory disturbances in PCAS by ... -
Comparative analysis of explainable machine learning prediction models for hospital mortality
Stenwig, Eline; Salvi, Giampiero; Salvo Rossi, Pierluigi; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2022)Background Machine learning (ML) holds the promise of becoming an essential tool for utilising the increasing amount of clinical data available for analysis and clinical decision support. However, the lack of trust in ... -
Comparison of correctly and incorrectly classified patients for in-hospital mortality prediction in the intensive care unit
Stenwig, Eline; Salvi, Giampiero; Salvo Rossi, Pierluigi; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2023)Background The use of machine learning is becoming increasingly popular in many disciplines, but there is still an implementation gap of machine learning models in clinical settings. Lack of trust in models is one of ... -
Post Cardiac Surgery Stunning Reduces Stroke Work, but Leaves Cardiac Power Output Unchanged in Patients with Normal Ejection Fraction
Tannvik, Tomas Dybos; Rimehaug, Audun Eskeland; Skjaervold, Nils Kristian; Kirkeby-Garstad, Idar (Journal article; Peer reviewed, 2018)This study assesses positional changes in cardiac power output and stroke work compared to classic haemodynamic variables, measured before and after elective coronary artery bypass graft surgery. The hypothesis was that ... -
Rapid declines in systolic blood pressure are associated with an increase in pulse transit time
Skjaervold, Nils Kristian; Schaanning, Sebastian (Peer reviewed; Journal article, 2020)Background The correlation between pulse transit time and blood pressure has been proposed as a route to measure continuous non-invasive blood pressure. We investigated whether pulse transit time trends could model blood ... -
Some oscillatory phenomena of blood glucose regulation: An exploratory pilot study in pigs
Skjaervold, Nils Kristian; Knai, Kathrine; Elvemo, Nicolas-Andreas L. (Journal article; Peer reviewed, 2018)It is well-known that blood glucose oscillates with a period of approximately 15 min (900 s) and exhibits an overall complex behaviour in intact organisms. This complexity is not thoroughly studied, and thus, we aimed to ... -
Swedish-Norwegian co-operation in the treatment of three hypothermia victims: a case report
Carlsen, Anders Wetting; Skjaervold, Nils Kristian; Berg, Nils K; Karlsen, Øystein; Gunnarsen, Eli; Wahba, Alexander (Journal article; Peer reviewed, 2017)Background: Accidental hypothermia with cardiac arrest represents a challenge for pre-hospital rescuers as well as in-hospital staff. For pre-hospital personnel, the main focus is to get the patient to the correct destination ... -
The coherence of macrocirculation, microcirculation, and tissue metabolic response during nontraumatic hemorrhagic shock in swine
Langeland, Halvor J.B.; Oddveig, Lyng; Petter, Aadahl; Skjaervold, Nils Kristian (Journal article; Peer reviewed, 2017)Hemorrhagic shock is clinically observed as changes in macrocirculatory indices, while its main pathological constituent is cellular asphyxia due to microcirculatory alterations. The coherence between macro‐ and microcirculatory ... -
Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study
Langeland, Halvor; Bergum, Daniel; Løberg, Magnus; Bjørnstad, Knut; Damås, Jan Kristian; Mollnes, Tom Eirik; Skjaervold, Nils Kristian; Klepstad, Pål (Journal article; Peer reviewed, 2018)Background: The post cardiac arrest syndrome (PCAS) is responsible for the majority of in-hospital deaths following cardiac arrest (CA). The major elements of PCAS are anoxic brain injury and circulatory failure. Objective: ... -
Visualisation of Limb Movements by Accelerometers in Sedated Patients
Harbo, Erlend; Fuglerud, Silje Skeide; Skjaervold, Nils Kristian (Peer reviewed; Journal article, 2020)The prognostication of neurological outcome in sedated ICU patients is challenging. Multiple clinical scoring schemes and examinations are used, where different motoric responses are important input variables. Accelerometery ...