• Identification and Tracking of Antiviral Drug Combinations 

      Ianevski, Aleksandr; Yao, Rouan; Biza, Svetlana; Zusinaite, Eva; Mannik, Andres; Kivi, Gaily; Planken, Anu; Kurg, Kristiina; Tombak, Eva-Maria; Ustav, Mart Jr; Shtaida, Nastassia; Kulesskiy, Evgeny; Jo, Eunji; Yang, Jaewon; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Aas, Per Arne; Tenson, Tanel; Vitkauskienė, Astra; Windisch, Marc P; Fenstad, Mona H.; Nordbø, Svein Arne; Ustav, Mart; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2020)
      Combination therapies have become a standard for the treatment for HIV and hepatitis C virus (HCV) infections. They are advantageous over monotherapies due to better efficacy, reduced toxicity, as well as the ability to ...
    • Low temperature and low UV indexes correlated with peaks of influenza virus activity in Northern Europe during 2010-2018 

      Ianevski, Aleksandr; Zusinaite, Eva; Shtaida, Nastassia; Kallio-Kokko, Hannimari; Valkonen, Mia; Kantele, Anu; Telling, Kaidi; Lutsar, Irja; Letjuka, Pille; Metelitsa, Natalja; Oksenych, Valentyn; Dumpis, Uga; Vitkauskiene, Astra; Stašaitis, Kestutis; Öhrmalm, Christina; Bondeson, Kåre; Bergqvist, Anders; Cox, Rebecca Jane; Tenson, Tanel; Merits, Andres; Kainov, Denis (Journal article; Peer reviewed, 2019)
      With the increasing pace of global warming, it is important to understand the role of meteorological factors in influenza virus (IV) epidemics. In this study, we investigated the impact of temperature, UV index, humidity, ...
    • Novel antiviral activities of obatoclax, emetine, niclosamide, brequinar, and homoharringtonine 

      Anderssen, Petter Inge; Krpina, Klara; Ianevski, Aleksandr; Shtaida, Nastassia; Jo, Eunji; Yang, Jaewon; Koit, Sandra; Tenson, Tanel; Hukkanen, Veijo; Anthonsen, Marit Walbye; Bjørås, Magnar; Evander, Magnus; Windisch, Marc P; Zusinaite, Eva; Kainov, Denis (Peer reviewed; Journal article, 2019)
      Viruses are the major causes of acute and chronic infectious diseases in the world. According to the World Health Organization, there is an urgent need for better control of viral diseases. Repurposing existing antiviral ...