Blar i NTNU Open på forfatter "Severi, Gianluca"
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The blood proteome of imminent lung cancer diagnosis
Albanes, Demetrius; Alcala, Karine; Alcala, Nicolas; Amos, Christopher I.; Arslan, Alan A.; Bassett, Julie K.; Brennan, Paul; Cai, Qiuyin; Chen, Chu; Feng, Xiaoshuang; Freedman, Neal D.; Guida, Florence; Hung, Rayjean J.; Hveem, Kristian; Johansson, Mikael; Johansson, Mattias; Koh, Woon-Puay; Langhammer, Arnulf; Milne, Roger L.; Muller, David; Onwuka, Justina; Sørgjerd, Elin Pettersen; Robbins, Hilary A.; Sesso, Howard D.; Severi, Gianluca; Shu, Xiao-Ou; Sieri, Sabina; Smith-Byrne, Karl; Stevens, Victoria; Tinker, Lesley; Tjønneland, Anne; Visvanathan, Kala; Wang, Ying; Wang, Renwei; Weinstein, Stephanie; Yuan, Jian-Min; Zahed, Hana; Zhang, Xuehong; Zheng, Wei (Peer reviewed; Journal article, 2023)Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched ... -
Cigarette Smoking and Endometrial Cancer Risk: Observational and Mendelian Randomization Analyses
Dimou, Niki; Omiyale, Wemimo; Biessy, Carine; Viallon, Vivian; Kaaks, Rudolf; O'Mara, Tracy A.; Aglago, Elom K.; Ardanaz, Eva; Bergmann, Manuela M.; Bondonno, Nicola P.; Braaten, Tonje; Colorado-Yohar, Sandra M.; Crous-Bou, Marta; Dahm, Christina C.; Fortner, Renée T.; Gram, Inger Torhild; Harlid, Sophia; Heath, Alicia K.; Idahl, Annika; Kvaskoff, Marina; Nøst, Therese Haugdahl; Overvad, Kim; Palli, Domenico; Perez-Cornago, Aurora; Sacerdote, Carlotta; Sánchez, Maria-Jose; Schulze, Matthias B.; Severi, Gianluca; Simeon, Vittorio; Tagliabue, Giovanna; Tjønneland, Anne; Truong, Thérése; Tumino, Rosario; Johansson, Mattias; Weiderpass, Elisabete; Murphy, Neil; Gunter, Marc J.; Lacey, Ben; Allen, Naomi E.; Dossus, Laure (Peer reviewed; Journal article, 2022)Background: Current epidemiologic evidence indicates that smoking is associated with a lower endometrial cancer risk. However, it is unknown if this association is causal or confounded. To further elucidate the role of ... -
Circulating concentrations of biomarkers and metabolites related to Vitamin status, one-carbon and the kynurenine pathways in US, Nordic, Asian, and Australian populations
Midttun, Øivind; Theofylaktopoulou, Despoina; Mccann, Adrian; Fanidi, Anouar; Muller, David C.; Meyer, Klaus; Ulvik, Arve; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Prentice, Ross; Thomson, Cynthia A.; Pettinger, Mary; Giles, Graham G.; Hodge, Allison; Cai, Qiuyin; Blot, William J.; Wu, Jie; Johansson, Mikael; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Sesso, Howard D.; Gaziano, J. Michael; Buring, Julie E.; Lee, I-Min; Severi, Gianluca; Zhang, Xuehong; Han, Jiali; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Yuan, Jian-Min; Butler, Lesley M.; Koh, Woon-Puay; Wang, Renwei; Gao, Yu-Tang; Ericson, Ulrika; Sonestedt, Emily; Ziegler, Regina G.; Freedman, Neal D.; Visvanathan, Kala; Jones, Miranda R.; Relton, Caroline; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Journal article; Peer reviewed, 2017)Background: Circulating concentrations of biomarkers that are related to vitamin status vary by factors such as diet, fortification, and supplement use. Published biomarker concentrations have also been influenced by the ... -
Circulating cotinine concentrations and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)
Larose, Tricia L; Guida, Florence; Anouar, Fanidi; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Jacobs, Eric J.; Smith-Warner, Stephanie A.; Giovannucci, Edward; Albanes, Demetrius; Weinstein, Stephanie J.; Freedman, Neal D.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loic; Wilkens, Lynne R.; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J; Hodge, Allison M.; Giles, Graham G.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Wang, Renwei; Yuan, Jian-Min; Gao, Yu-Tang; Koh, Woon-Puay; Shu, Xiao-Ou; Zheng, Wei; Xiang, Yong-Bing; Li, Honglan; Lan, Qing; Visvanathan, Kala; Hoffman Bolton, Judith; Ueland, Per Magne; Midttun, Øivind; Caporaso, Neil; Purdue, Mark; Sesso, Howard D.; Buring, Julie E.; Lee, I-Min; Gaziano, J. Michael; Manjer, Jonas; Brunnström, Hans; Brennan, Paul; Johansson, Mattias (Journal article; Peer reviewed, 2018)Background Self-reported smoking is the principal measure used to assess lung cancer risk in epidemiological studies. We evaluated if circulating cotinine—a nicotine metabolite and biomarker of recent tobacco exposure—provides ... -
Circulating high sensitivity C reactive protein concentrations and risk of lung cancer: Nested case-control study within Lung Cancer Cohort Consortium
Muller, David C.; Larose, Tricia L; Hodge, Allison; Guida, Florence; Langhammer, Arnulf; Grankvist, Kjell; Meyer, Klaus; Cai, Qiuyin; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Albanes, Demetrius; Giles, Graham G.; Sesso, Howard D.; Lee, I-Min; Gaziano, J. Michael; Yuan, Jian-Min; Hoffman Bolton, Judith; Buring, Julie E.; Visvanathan, Kala; Le Marchand, Loic; Purdue, Mark P.; Caporaso, Neil E.; Midttun, Øivind; Ueland, Per Magne; Prentice, Ross L.; Weinstein, Stephanie J.; Stevens, Victoria L.; Zheng, Wei; Blot, William J.; Shu, Xiao-Ou; Zhang, Xuehong; Xiang, Yong-Bing; Koh, Woon-Puay; Hveem, Kristian; Thomson, Cynthia A.; Pettinger, Mary; Engström, Gunnar; Brunnström, Hans; Milne, Roger L.; Stampfer, Meir J.; Han, Jiali; Johansson, Mikael; Brennan, Paul; Severi, Gianluca; Johansson, Mattias (Journal article; Peer reviewed, 2019)Objectives: Inflammation may play an important role in lung cancer pathogenesis. Previous studies have suggested an association between C-reactive protein (CRP) as a marker of inflammation, and risk of lung cancer, but ... -
Circulating markers of cellular immune activation in pre-diagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3)
Huang, Joyce Yongxu; Larose, Tricia L; Luu, Hung N; Wang, Renwei; Fanidi, Anouar; Alcala, Karine; Stevens, Victoria L.; Weinstein, Stephanie J.; Albanes, Demetrius; Caporaso, Neil E.; Purdue, Mark P.; Ziegler, Regina G.; Freedman, Neal D.; Lan, Qing; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Cai, Qiuyin; Wu, Jie; Blot, William J.; Shu, Xiao-Ou; Zheng, Wei; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Le Marchand, Loïc; Wilkens, Lynn R; Haiman, Christopher A.; Zhang, Xuehong; Stampfer, Meir J.; Han, Jiali; Giles, Graham G.; Hodge, Allison M.; Severi, Gianluca; Johansson, Mikael; Grankvist, Kjell; Langhammer, Arnulf; Hveem, Kristian; Xiang, Yong-Bing; Li, Hong-Lan; Gao, Yu-Tang; Visvanathan, Kala; Ueland, Per Magne; Midttun, Øivind; Ulvik, Arve; Buring, Julie E.; Lee, I-Min; Sesso, Howard D.; Gaziano, J. Michael; Manjer, Jonas; Relton, Caroline; Koh, Woon-Puay; Brennan, Paul; Johansson, Mattias; Yuan, Jian-Min (Journal article; Peer reviewed, 2019)Cell‐mediated immune suppression may play an important role in lung carcinogenesis. We investigated the associations for circulating levels of tryptophan, kynurenine, kynurenine:tryptophan ratio (KTR), quinolinic acid (QA) ... -
Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking
Petrovic, Dusan; Bodinier, Barbara; Dagnino, Sonia; Whitaker, Matthew; Karimi, Maryam; Campanella, Gianluca; Nøst, Therese Haugdahl; Polidoro, Silvia; Palli, Domenico; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Lund, Eiliv; Dugué, Pierre-Antoine; Giles, Graham G; Severi, Gianluca; Southey, Melissa; Vineis, Paolo; Stringhini, Silvia; Bochud, Murielle; Sandanger, Torkjel M; Vermeulen, Roel CH; Guida, Florence; Chadeau-Hyam, Marc (Peer reviewed; Journal article, 2022)Smoking-related epigenetic changes have been linked to lung cancer, but the contribution of epigenetic alterations unrelated to smoking remains unclear. We sought for a sparse set of CpG sites predicting lung cancer and ... -
Genome-wide association study identifies multiple risk loci for renal cell carcinoma
Scelo, Ghislaine; Purdue, Mark P.; Brown, Kevin M.; Johansson, Mattias; Wang, Zhaoming; Eckel-Passow, Jeanette E.; Ye, Yuanqing; Hofmann, Jonathan N.; Choi, Jiyeon; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Sampson, Joshua N.; Abedi-Ardekani, Behnoush; Besse, Celine; Blanche, Helene; Boland, Anne; Burdette, Laurie; Chabrier, Amelie; Durand, Geoffroy; Le Calvez-Kelm, Florence; Prokhortchouk, Egor; Robinot, Nivonirina; Skryabin, Konstantin G.; Wozniak, Magdalena B.; Yeager, Meredith; Basta-Jovanovic, Gordana; Dzamic, Zoran; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Szeszenia-Dabrowska, Neonila; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Baglietto, Laura; Boeing, Heiner; Khaw, Kay-Tee; Weiderpass, Elisabete; Ljungberg, Börje; Sitaram, Raviprakash T.; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Koppova, Kvetoslava; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Pharoah, Paul; Andreotti, Gabriella; Freeman, Laura E Beane; Koutros, Stella; Albanes, Demetrius; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Kraft, Peter; Preston, Mark A.; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Black, Amanda; Freedman, Neal D.; Huang, Wen-Yi; Anema, John G.; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Wood, Christopher; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Rothman, Nathaniel; Deleuze, Jean-Francois; McKay, James D.; Parker, Alexander S.; Wu, Xifeng; Houlston, Richard S.; Brennan, Paul; Chanock, Stephen J. (Journal article; Peer reviewed, 2017)Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing ... -
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Peer reviewed; Journal article, 2023)Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available ... -
No association between circulating concentrations of vitamin D and risk of lung cancer: An analysis in 20 prospective studies in the Lung Cancer Cohort Consortium (LC3)
Muller, David C.; Hodge, Allison M.; Fanidi, Anouar; Albanes, Demetrius; Mai, Xiao-Mei; Shu, Xiao Ou; Weinstein, Stephanie J.; Larose, Tricia L; Zhang, Xuehong; Han, Jingquan; Stampfer, Meir J.; Smith-Warner, Stephanie A.; Ma, Jing; Gaziano, John Michael; Sesso, Howard D.; Stevens, Victoria L.; McCullough, Marjorie L.; Layne, Tracy M.; Prentice, Ross; Pettinger, Mary; Thomson, Cynthia A.; Zheng, Wei; Gao, Yutang; Rothman, Nathaniel; Xiang, Yong-Bing; Cai, Hui; Wang, Rui; Yuan, Jian-Min; Koh, Woon-Puay; Butler, Lesley M.; Cai, Qiuyin; Blot, William James; Wu, Jie; Ueland, Per Magne; Midttun, Øivind; Langhammer, Arnulf; Hveem, Kristian; Johansson, Mikael B.; Hultdin, Johan; Grankvist, Kjell; Arslan, Alan A.; Le Marchand, Loïc; Severi, Gianluca; Johansson, Mattias; Brennan, Paul (Journal article; Peer reviewed, 2018)Background There is observational evidence suggesting that high vitamin D concentrations may protect against lung cancer. To investigate this hypothesis in detail, we measured circulating vitamin D concentrations in ... -
Prediagnosis Leisure-Time Physical Activity and Lung Cancer Survival: A Pooled Analysis of 11 Cohorts
Yang, Jae Jeong; Yu, Danxia; White, Emily; Lee, Dong Hoon; Blot, William; Robien, Kim; Sinha, Rashmi; Park, Yikyung; Takata, Yumie; Gao, Yu-Tang; Smith-Byrne, Karl; Monninkhof, Evelyn M; Kaaks, Rudolf; Langhammer, Arnulf; Borch, Kristin Benjaminsen; Al-Shaar, Laila; Lan, Qing; Sørgjerd, Elin Pettersen; Zhang, Xuehong; Zhu, Clair; Chirlaque, María Dolores; Severi, Gianluca; Overvad, Kim; Sacerdote, Carlotta; Aune, Dagfinn; Johansson, Mattias; Smith-Warner, Stephanie A; Zheng, Wei; Shu, Xiao-Ou (Peer reviewed; Journal article, 2022)Background Little is known about the association between physical activity before cancer diagnosis and survival among lung cancer patients. In this pooled analysis of 11 prospective cohorts, we investigated associations ... -
Prediagnostic calcium intake and lung cancer survival: A pooled analysis of 12 cohort studies
Yu, Danxia; Takata, Yumie; Smith-Warner, Stephanie A.; Blot, William; Sawada, Norie; White, Emily; Freedman, Neal; Robien, Kim; Giovannucci, Edward; Zhang, Xuehong; Park, Yikyung; Gao, Yu-Tang; Chlebowski, Rowan T.; Langhammer, Arnulf; Yang, Gong; Severi, Gianluca; Manjer, Jonas; Khaw, Kay-Tee; Weiderpass, Elisabete; Liao, Linda M.; Caporaso, Neil; Krokstad, Steinar; Hveem, Kristian; Sinha, Rashmi; Ziegler, Regina; Tsugane, Shoichiro; Xiang, Yong-Bing; Johansson, Mattias; Zheng, Wei; Shu, Xiao-Ou (Journal article, 2017)Background: Lung cancer is the leading cause of cancer death. Little is known about whether prediagnostic nutritional factors may affect survival. We examined the associations of prediagnostic calcium intake from foods ... -
The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study
Johansson, Mattias; Carreras-Torres, Robert; Scelo, Ghislaine; Purdue, Mark P.; Mariosa, Daniela; Muller, David C.; Timpson, Nicholas J.; Haycock, Philip C.; Brown, Kevin M.; Wang, Zhaoming; Ye, Yuanqing; Hofmann, Jonathan N.; Foll, Matthieu; Gaborieau, Valerie; Machiela, Mitchell J.; Colli, Leandro M.; Li, Peng; Garnier, Jean-Guillaume; Blanche, Helene; Boland, Anne; Burdette, Laurie; Prokhortchouk, Egor; Skryabin, Konstantin G.; Yeager, Meredith; Radojevic-Skodric, Sanja; Ognjanovic, Simona; Foretova, Lenka; Holcatova, Ivana; Janout, Vladimir; Mates, Dana; Mukeriya, Anush; Rascu, Stefan; Zaridze, David; Bencko, Vladimir; Cybulski, Cezary; Fabianova, Eleonora; Jinga, Viorel; Lissowska, Jolanta; Lubinski, Jan; Navratilova, Marie; Rudnai, Peter; Benhamou, Simone; Cancel-Tassin, Geraldine; Cussenot, Olivier; Weiderpass, Elisabete; Ljungberg, Börje; Tumkur Sitaram, Raviprakash; Häggström, Christel; Bruinsma, Fiona; Jordan, Susan J.; Severi, Gianluca; Winship, Ingrid; Hveem, Kristian; Vatten, Lars Johan; Fletcher, Tony; Larsson, Susanna C.; Wolk, Alicja; Banks, Rosamonde E.; Selby, Peter J.; Easton, Douglas F.; Andreotti, Gabriella; Beane Freeman, Laura E.; Koutros, Stella; Männistö, Satu; Weinstein, Stephanie; Clark, Peter E.; Edwards, Todd L.; Lipworth, Loren; Gapstur, Susan M.; Stevens, Victoria L.; Carol, Hallie; Freedman, Matthew L.; Pomerantz, Mark M.; Cho, Eunyoung; Wilson, Kathryn M.; Gaziano, J. Michael; Sesso, Howard D.; Freedman, Neal D.; Parker, Alexander S.; Eckel-Passow, Jeanette E.; Huang, Wen-Yi; Kahnoski, Richard J.; Lane, Brian R.; Noyes, Sabrina L.; Petillo, David; Teh, Bin Tean; Peters, Ulrike; White, Emily; Anderson, Garnet L.; Johnson, Lisa; Luo, Juhua; Buring, Julie; Lee, I-Min; Chow, Wong-Ho; Moore, Lee E.; Eisen, Timothy; Henrion, Marc; Larkin, James; Barman, Poulami; Leibovich, Bradley C.; Choueiri, Toni K.; Lathrop, G. Mark; Deleuze, Jean-François; Gunter, Marc; McKay, James D.; Wu, Xifeng; Houlston, Richard S.; Chanock, Stephen J.; Relton, Caroline; Richards, J. Brent; Martin, Richard M.; Davey Smith, George; Brennan, Paul (Journal article; Peer reviewed, 2019)Background Several obesity-related factors have been associated with renal cell carcinoma (RCC), but it is unclear which individual factors directly influence risk. We addressed this question using genetic markers as ... -
Vitamin B6 catabolism and lung cancer risk: Results from the Lung Cancer Cohort Consortium (LC3)
Zuo, Hui; Ueland, Per Magne; Midttun, Øivind; Tell, Grethe S.; Fanidi, Anouar; Zheng, Wei; Shu, Xiao-Ou; Xiang, Yong-Bing; Wu, Jie; Prentice, Ross L.; Pettinger, Mary; Thomson, Cynthia A.; Giles, Graham G.; Hodge, Allison M.; Cai, Qiuyin; Blot, William J.; Johansson, Mikael B.; Hultdin, Johan; Grankvist, Kjell; Stevens, Victoria L.; McCullough, Marjorie L.; Weinstein, Stephanie J.; Albanes, Demetrius; Ziegler, Regina G.; Freedman, Neal David; Caporaso, Neil E.; Langhammer, Arnulf; Hveem, Kristian; Næss, Marit; Buring, Julie E.; Lee, I-Min; Gaziano, John Michael; Severi, Gianluca; Zhang, Xuehong; Stampfer, Meir Jonathan; Han, Jiali; Zeleniuch-Jacquotte, Anne; Marchand, Loïc Le; Yuan, Jian-Min; Wang, Renwei; Koh, Woon-Puay; Gao, Yutang; Ericson, Ulrika C.; Visvanathan, Kala; Jones, Michael R.; Relton, Caroline Laura; Brennan, Paul J.; Johansson, Mattias; Ulvik, Arve (Journal article; Peer reviewed, 2019)Background Increased vitamin B6 catabolism related to inflammation, as measured by the PAr index (the ratio of 4-pyridoxic acid over the sum of pyridoxal and pyridoxal-5'-phosphate), has been positively associated with ...