• Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium 

      Robbins, Hilary A.; Ferreiro-Iglesias, Aida; Waterboer, Tim; Brenner, Nicole; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Allan; Pawlita, Michael; D'Souza, Gypsyamber; Visvanathan, Kala; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley F.; Agalliu, Ilir; Wassertheil-Smoller, Sylvia; Ness-Jensen, Eivind; Hveem, Kristian; Grioni, Sara; Kaaks, Rudolf; Sánchez, Maria-Jose; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Huang, Wen-Yi; Freedman, Neal D.; Kreimer, Aimée R; Johansson, Mattias; Brennan, Paul (Peer reviewed; Journal article, 2022)
      PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. METHODS We ...
    • Timing of HPV16-E6 antibody seroconversion before OPSCC: Findings from the HPVC3 consortium 

      Kreimer, Aimée R.; Ferreiro-Iglesias, Aida; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Alan; Robbins, Hilary A.; Pawlita, Michael; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley Fels; Agalliu, Ilir; Smoller, Sylvia W.; Ness-Jensen, Eivind; Hveem, Kristian; D'Souza, Gypsyamber; Visvanathan, Kala; May, Betty; Ursin, Giske; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Brenner, Nicole; Hoffman-Bolton, Judith; Kaaks, Rudolf; Barricarte, Aurelio; Tjønneland, Anne; Sacerdote, Carlotta; Trichopoulou, Antonia; Vermeulen, Roel C.H.; Huang, Wen-Yi; Freedman, Neal D.; Brennan, Paul J.; Waterboer, Tim; Johansson, Mattias (Journal article; Peer reviewed, 2019)
      Background Human papillomavirus type 16 (HPV16)-E6 antibodies are detectable in peripheral blood before diagnosis in the majority of HPV16-driven oropharyngeal squamous cell carcinoma (OPSCC), but the timing of seroconversion ...