• LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium 

      Zwiggelaar, Rosalie; Lindholm, Håvard Takle; Fosslie, Madeleine Lystad; Pedersen, Marianne Terndrup; Ohta, Yuki; Díez-Sánchez, Alberto; Martín-Alonso, Mara; Ostrop, Jenny; Matono, Mami; Parmar, Naveen; Kvaløy, Emilie; Spanjers, Roos; Nazmi, Kamran; Rye, Morten Beck; Drabløs, Finn; Arrowsmith, Cheryl H; Dahl, John Arne; Jensen, Kim B.; Sato, Toshiro; Oudhoff, Menno (Journal article; Peer reviewed, 2020)
      Intestinal epithelial homeostasis is maintained by adult intestinal stem cells, which, alongside Paneth cells, appear after birth in the neonatal period. We aimed to identify regulators of neonatal intestinal epithelial ...
    • SETD7 Controls Intestinal Regeneration and Tumorigenesis by Regulating Wnt/β-Catenin and Hippo/YAP Signaling 

      Oudhoff, Menno; Braam, Mitchell JS; Freeman, Spencer A; Wong, Denise; Rattray, David G; Wang, Jia; Antignano, Frann; Snyder, Kimberly; Refaeli, Ido; Hughes, Michael R; McNagny, Kelly M; Gold, Michael R; Arrowsmith, Cheryl H; Sato, Toshiro; Rossi, Fabio MV; Tatlock, John H; Owen, Dafydd R; Brown, Peter J; Zaph, Colby (Journal article; Peer reviewed, 2016)
      Intestinal tumorigenesis is a result of mutations in signaling pathways that control cellular proliferation, differentiation, and survival. Mutations in the Wnt/β-catenin pathway are associated with the majority of intestinal ...