• A systemic study of lipid metabolism regulation in salmon fingerlings and early juveniles fed plant oil 

      Jin, Yang; Olsen, Rolf Erik; Gillard, Gareth B.; Østensen, Mari-Ann; Korsvoll, Sven A.; Santi, Nina; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)
      In salmon farming, the scarcity of fish oil has driven a shift towards the use of plant-based oil from vegetable or seed, leading to fish feed low in long-chain PUFA (LC-PUFA) and cholesterol. Atlantic salmon has the ...
    • Atlantic salmon raised with diets low in long-chain polyunsaturated n-3 fatty acids in freshwater have a Mycoplasma-dominated gut microbiota at sea 

      Jin, Yang; Angell, Inga Leena; Sandve, Simen Rød; Snipen, Lars-Gustav; Olsen, Yngvar; Rudi, Knut (Journal article; Peer reviewed, 2019)
      Factors affecting the establishment of the gut microbiota in animals living in marine environments remain largely unknown. In terrestrial animals, however, it is well established that the juvenile environment has a major ...
    • Comparative transcriptomics reveals domestication‐associated features of Atlantic salmon lipid metabolism 

      Jin, Yang; Olsen, Rolf Erik; Harvey, Thomas Nelson; Østensen, Mari-Ann; Li, Keshuai; Santi, Nina; Vadstein, Olav; Bones, Atle M.; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Peer reviewed; Journal article, 2020)
      Domestication of animals imposes strong targeted selection for desired traits but can also result in unintended selection due to new domestic environments. Atlantic salmon was domesticated in the 1970s and has subsequently ...
    • Development of lipid metabolism in early life stages of Atlantic salmon (Salmo salar) 

      Jin, Yang (Doctoral theses at NTNU;2019:47, Doctoral thesis, 2019)
      Development of lipid metabolism in early life stages of Atlantic salmon (Salmo salar) Larval and juvenile stages are critical periods for Atlantic salmon (Salmo salar), which can have a major impact on growth and ...
    • Diet and Life Stage-Associated Lipidome Remodeling in Atlantic Salmon 

      Jin, Yang; Harvey, Thomas Nelson; Bartosova, Zdenka; Hassani, Sahar; Bruheim, Per; Sandve, Simen Rød; Vik, Jon Olav (Peer reviewed; Journal article, 2021)
      Salmon is an important source of long-chain highly unsaturated fatty acids (LC-HUFAs) such as 22:6n-3 [docosahexaenoic acid (DHA)]. In the present study, we conducted two identical experiments on salmon in freshwater (FW) ...
    • Functional Annotation of All Salmonid Genomes (FAASG): an international initiative supporting future salmonid research, conservation and aquaculture 

      Macqueen, Daniel J.; Primmer, Craig R.; Houston, Ross D.; Nowak, Barbara F.; Bernatchez, Louis; Bergseth, Steinar; Davidson, William S.; Gallardo-Escárate, Cristian; Goldammer, Tom; Guiguen, Yann; Iturra, Patricia; Kijas, James W.; Koop, Ben F.; Lien, Sigbjørn; Maass, Alejandro; Martin, Samuel A. M.; McGinnity, Philip; Montecino, Martin; Naish, Kerry; Nichols, Krista M.; Ólafsson, Kristinn; Omholt, Stig William; Palti, Yniv; Plastow, Graham S.; Rexroad, Caird E. 3rd; Rise, Matthew L.; Ritchie, Rachael J.; Sandve, Simen Rød; Schulte, Patricia M.; Tello, Alfredo; Vidal, Rodrigo; Vik, Jon Olav; Wargelius, Anna; Yáñez, José Manuel (Journal article; Peer reviewed, 2017)
      We describe an emerging initiative - the ‘Functional Annotation of All Salmonid Genomes’ (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in the salmonid ...
    • Life-stage associated remodeling of lipid metabolism regulation in Atlantic salmon 

      Gillard, Gareth Benjamin; Harvey, Thomas Nelson; Gjuvsland, Arne Bjørke; Jin, Yang; Thomassen, Magny Sissel S.; Lien, Sigbjørn; Leaver, Michael; Torgersen, Jacob Seilø; Hvidsten, Torgeir Rhoden; Vik, Jon Olav; Sandve, Simen Rød (Journal article; Peer reviewed, 2018)
      Atlantic salmon migrates from rivers to sea to feed, grow and develop gonads before returning to spawn in freshwater. The transition to marine habitats is associated with dramatic changes in the environment, including water ...
    • Mid and hindgut transcriptome profiling analysis of Atlantic salmon (Salmon salar) under unpredictable chronic stress 

      Løvmo, Signe Dille; Madaro, Angelico; Whatmore, Paul; Bardal, Tora; Østensen, Mari-Ann; Sandve, Simen Rød; Olsen, Rolf Erik (Peer reviewed; Journal article, 2020)
      The intestinal epithelium is a selectively permeable barrier for nutrients, electrolytes and water, while maintaining effective protection against pathogens. Combinations of stressors throughout an animal's life, especially ...
    • Molecular Regulation of Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Atlantic Salmon 

      Datsomor, Alex Kojo; Gillard, Gareth Benjamin; Jin, Yang; Olsen, Rolf Erik; Sandve, Simen Rød (Peer reviewed; Journal article, 2022)
      Salmon is a rich source of health-promoting omega-3 long chain polyunsaturated fatty acids (n-3 LC-PUFA), such as eicosapentaenoic acid (EPA, 20:5n-3) and docosahexaenoic acid (DHA, 22:6n-3). The LC-PUFA biosynthetic pathway ...
    • The Atlantic salmon genome provides insights into rediploidization 

      Lien, Sigbjørn; Koop, Ben F; Sandve, Simen Rød; Miller, Jason R.; Kent, Matthew Peter; Nome, Torfinn; Hvidsten, Torgeir Rhoden; Leong, Jong; Minkley, David R.; Zimin, Aleksey; Grammes, Fabian; Grove, Harald; Gjuvsland, Arne Bjørke; Walenz, Brian; Hermansen, Russell A.; von Schalburg, Kristian R.; Rondeau, Eric; Genova, Alex Di; Antony Samy, Jeevan Karloss; Vik, Jon Olav; Vigeland, Magnus Dehli; Caler, Lis; Grimholt, Unni; Jentoft, Sissel; Våge, Dag Inge; de Jong, Pieter J.; Moen, Thomas; Baranski, Matthew; Palti, Yniv; Smith, Douglas W.; Yorke, James A.; Nederbragt, Alexander J.; Tooming-Klunderud, Ave; Jakobsen, Kjetill Sigurd; Jiang, Xuanting; Fan, Dingding; Hu, Yan; Liberles, David A.; Vidal, Rodrigo; Iturra, Patricia; Jones, Steven J.M.; Jonassen, Inge; Maass, Alejandro; Omholt, Stig William; Davidson, William S (Journal article; Peer reviewed, 2016)
      The whole-genome duplication 80 million years ago of the common ancestor of salmonids (salmonid-specific fourth vertebrate whole-genome duplication, Ss4R) provides unique opportunities to learn about the evolutionary fate ...
    • Transcriptional development of phospholipid and lipoprotein metabolism in different intestinal regions of Atlantic salmon (Salmo salar) fry 

      Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Korsvoll, Sven Arild; Santi, Nina; Gjuvsland, Arne Bjørke; Vik, Jon Olav; Torgersen, Jacob Seilø; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)
      Background It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced ...
    • Transcriptional regulation of lipid metabolism when salmon fry switches from endogenous to exogenous feeding 

      Jin, Yang; Olsen, Rolf Erik; Østensen, Mari-Ann; Gillard, Gareth Benjamin; Li, Keshuai; Harvey, Thomas Nelson; Santi, Nina; Vadstein, Olav; Vik, Jon Olav; Sandve, Simen Rød; Olsen, Yngvar (Journal article; Peer reviewed, 2018)
      The onset of first feeding is a critical period for Atlantic salmon (Salmo salar). The fish goes through a dramatic transition, from using the yolk sac as an energy and nutrient resource to rely on exogenous food. However, ...