Browsing NTNU Open by Author "Sakshaug, Teri"
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Age- and sex-dependent effects of DNA glycosylase Neil3 on amyloid pathology, adult neurogenesis, and memory in a mouse model of Alzheimer's disease
Egiazarian, Milena Armenovna; Strømstad, Silje; Sakshaug, Teri; Nunez-Nescolarde, Ana; Bethge, Nicole; Bjørås, Magnar; Scheffler, Katja (Peer reviewed; Journal article, 2022)Oxidative stress generating DNA damage has been shown to be a key characteristic in Alzheimer's disease (AD). However, how it affects the pathogenesis of AD is not yet fully understood. Neil3 is a DNA glycosylase initiating ... -
Organization of Posterior Parietal–Frontal Connections in the Rat
Olsen, Grethe Mari; Hovde, Karoline; Kondo, Hideki; Sakshaug, Teri; Haaland Sømme, Hanna; Whitlock, Jonathan; Witter, Menno (Journal article; Peer reviewed, 2019)Recent investigations of the rat posterior parietal cortex (PPC) suggest that this region plays a central role in action control together with the frontal cortical areas. Posterior parietal-frontal cortical connections ... -
Projections of the orbitofrontal cortex to the parietal cortex in the rat
Sakshaug, Teri (Master thesis, 2015)The orbitofrontal cortex (OFC) has been shown to play a role in decision making and goal oriented behaviors. The parietal cortex has also been shown to contribute to goal oriented behaviors and movements. Though cell ... -
The regulation of neuroinflammation by oxidative DNA base lesion repair
Sakshaug, Teri (Master thesis, 2020)Current research shows that altered microglia activity and persistent neuroinflammation are underlying factors to neurological diseases such as Alzheimer's, Parkinson's, multiple sclerosis and psychiatric illnesses. ... -
The Role of DNA Glycosylases and Sex in Stress Susceptibility
Salvesen, Hedda Kjelsaas (Master thesis, 2024)Vanlige psykiske lidelser som depresjon og angst spiller en vesentlig rolle for menneskers generelle helse og funksjonsnedsettelse over hele verden. Forekomsten av begge lidelsene er høyere blant kvinner sammenlignet med ...