Browsing NTNU Open by Author "Sørdal, Øystein Finset"
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Expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma
Mjønes, Patricia; Nordrum, Ivar Skjåk; Qvigstad, Gunnar; Sørdal, Øystein Finset; Rian, Liselotte Linnea Mårtensson; Waldum, Helge (Journal article; Peer reviewed, 2017)The aim of the study was to investigate the expression of erythropoietin and neuroendocrine markers in clear cell renal cell carcinoma (CCRCC). We retrospectively reviewed the medical records and re-evaluated histopathological ... -
Expression of the Cholecystokinin-B Receptor in Neoplastic Gastric Cells
Mjønes, Patricia; Nordrum, Ivar Skjåk; Sørdal, Øystein Finset; Sagatun, Liv; Fossmark, Reidar; Sandvik, Arne Kristian; Waldum, Helge (Journal article, 2017)Gastric cancer is an important disease due to its high mortality. Despite the decline in frequency, most cases are discovered late in its course, and most of the cancer patients die within a few years of diagnosis. In ... -
Helicobacter pylori and gastric acid: An intimate and reciprocal relationship
Waldum, Helge Lyder; Kleveland, Per Martin; Sørdal, Øystein Finset (Peer reviewed; Journal article, 2016)Helicobacter pylori (Hp) is the main cause of gastritis, peptic ulcer disease and gastric cancer. There are still unanswered questions related to the interaction between Hp and man, like what determines the susceptibility ... -
Is empiric proton pump inhibition in patients with symptoms of extraesophageal gastroesophageal reflux justified?
Fossmark, Reidar; Ness-Jensen, Eivind; Sørdal, Øystein Finset (Peer reviewed; Journal article, 2023)Background The prevalence of gastroesophageal reflux disease (GERD) has had a marked increase in Western countries with a paralleling interest in extraesophageal (EE) manifestations of GERD, including laryngopharyngeal ... -
Not only stem cells, but also mature cells, particularly neuroendocrine cells, may develop into tumours: time for a paradigm shift
Waldum, Helge; Öberg, Kjell; Sørdal, Øystein Finset; Sandvik, Arne Kristian; Gustafsson, Björn; Mjønes, Patricia; Fossmark, Reidar (Journal article; Peer reviewed, 2018)Stem cells are considered the origin of neoplasms in general, and malignant tumours in particular, and the stage at which the stem cells stop their differentiation determines the degree of malignancy. However, there is ... -
The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival
Vange, Pål; Bruland, Torunn; Doseth, Berit; Fossmark, Reidar; Sousa, Mirta; Beisvag, Vidar; Sørdal, Øystein Finset; Qvigstad, Gunnar; Waldum, Helge; Sandvik, Arne Kristian; Bakke, Ingunn (Journal article; Peer reviewed, 2017)The cytoprotective protein clusterin is often dysregulated during tumorigenesis, and in the stomach, upregulation of clusterin marks emergence of the oxyntic atrophy (loss of acid-producing parietal cells)-associated ... -
The enterochromaffin-like [ECL] cell-central in gastric physiology and pathology
Waldum, Helge; Sørdal, Øystein Finset; Mjønes, Patricia (Journal article; Peer reviewed, 2019)Background: Studies on the regulation of gastric and pancreatic secretion began more than 100 years ago. Secretin was the first hormone postulated to exist, initiating the field of endocrinology. Gastrin produced in the ...