• A prospective three-year follow-up study on the clinical significance of anti-neuronal antibodies in acute psychiatric disorders 

      Schou, Morten Brix; Sæther, Sverre Georg; Drange, Ole Kristian; Brenner, Eiliv; Crespi, Joan Vidal; Eikenes, Live; Mykland, Martin Syvertsen; Pintzka, Carl Wolfgang Schøyen; Håberg, Asta; Sand, Trond; Vaaler, Arne; Kondziella, Daniel (Peer reviewed; Journal article, 2019)
      The clinical significance of anti-neuronal antibodies for psychiatric disorders is controversial. We investigated if a positive anti-neuronal antibody status at admission to acute psychiatric inpatient care was associated ...
    • Biomarkers of Systemic and Neuronal Autoimmunity in Acute Psychiatric Disorders 

      Sæther, Sverre Georg (Doctoral theses at NTNU;2018:179, Doctoral thesis, 2018)
      Summary: Introduction and aims: Patients with autoimmune disorders with autoantibodies against systemic and neuronal targets frequently present with neuropsychiatric symptoms. The literature on the prevalence and clinical ...
    • Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study 

      Drange, Ole Kristian; Sæther, Sverre Georg; Finseth, Per Ivar; Morken, Gunnar; Vaaler, Arne; Arntsen, Vibeke; Henning, Oliver Johannes; Andreassen, Ole Andreas; Elvsåshagen, Torbjørn; Malt, Ulrik Fredrik; Bøen, Erlend (Peer reviewed; Journal article, 2020)
      Background A diagnosis of bipolar II disorder requires that the symptoms cannot be better explained by a medical condition. Epilepsy is in some cases associated with an affective syndrome mimicking an unstable bipolar ...
    • Epilepsy and other seizure disorders in acute psychiatric inpatients 

      Nakken, Erlend Iversen; Grinde, Frithjof; Vaaler, Arne; Drange, Ole Kristian; Brodtkorb, Eylert; Sæther, Sverre Georg (Peer reviewed; Journal article, 2021)
      Background: It is well known that patients with epilepsy have a high rate of psychiatric comorbidity. However, studies exploring epilepsy in psychiatric cohorts are scarce. The aim of this study was to examine the prevalence ...
    • Epitope specificity of anti-synapsin autoantibodies: Differential targeting of synapsin I domains 

      Mertens, Robert; Melchert, Sarah; Gitler, Daniel; Schou, Morten Brix; Sæther, Sverre Georg; Vaaler, Arne; Piepgras, Johannes; Kochova, Elena; Benfenati, Fabio; Ahnert-Hilger, Gudrun; Ruprecht, Klemens; Höltje, Markus (Journal article; Peer reviewed, 2018)
      Objective To identify the specific domains of the presynaptic protein synapsin targeted by recently described autoantibodies to synapsin. Methods Sera of 20 and CSF of two patients with different psychiatric and ...
    • Fylkesvise forskjeller i forskrivning av klozapin 

      Schou, Morten Brix; Drange, Ole Kristian; Sæther, Sverre Georg (Peer reviewed; Journal article, 2019)
      BAKGRUNN Nasjonale retningslinjer anbefaler å tilby klozapin til pasienter med schizofreni etter to mislykkede forsøk med andre antipsykotiske legemidler. En av hovedmålsettingene med innføringen av pakkeforløp i psykisk ...
    • Onconeural Antibodies in Acute Psychiatric Inpatient Care 

      Sæther, Sverre Georg; Schou, Morten Brix; Stoecker, W; Teegen, B; Borowski, K; Vaaler, Arne Einar; Kondziella, Daniel; Reitan, Solveig Merete Klæbo (Journal article; Peer reviewed, 2016)
      Paraneoplastic neurological disorders associated with onconeural antibodies often appear with neuropsychiatric symptoms. To study the prevalence of onconeural antibodies in patients admitted to acute psychiatric inpatient ...
    • Prevalence of serum anti-neuronal autoantibodies in patients admitted to acute psychiatric care 

      Schou, Morten Brix; Sæther, Sverre Georg; Borowski, K; Teegen, B; Kondziella, Daniel; Stoecker, W; Vaaler, Arne Einar; Reitan, Solveig Merete Klæbo (Journal article; Peer reviewed, 2016)
      Background Autoimmune encephalitis associated with anti-neuronal antibodies may be challenging to distinguish from primary psychiatric disorders. The significance of anti-neuronal antibodies in psychiatric patients without ...
    • Subtle Phenotype Differences in Psychiatric Patients With and Without Serum Immunoglobulin G Antibodies to Synapsin 

      Sæther, Sverre Georg; Vaaler, Arne; Evjenth, Anita; Aune, Therese Lie; Höltje, Markus; Ruprecht, Klemens; Schou, Morten Brix (Journal article; Peer reviewed, 2019)
      The discovery that antibodies targeting neuronal antigens can induce severe psychiatric symptoms has been a significant progress in the understanding of psychiatric disorders. Antibodies targeting synapsin I in serum and ...
    • The significance of anti-neuronal antibodies for acute psychiatric disorders: a retrospective case-controlled study 

      Schou, Morten Brix; Sæther, Sverre Georg; Drange, Ole Kristian; Krane-Gartiser, Karoline; Reitan, Solveig Merete Klæbo; Vaaler, Arne; Kondziella, Daniel (Journal article; Peer reviewed, 2018)
      Background The clinical significance of anti-neuronal antibodies in patients with psychiatric disorders, but without encephalitis, remains unknown. In patients admitted to acute psychiatric inpatient care we aimed to ...
    • What is the significance of onconeural antibodies for psychiatric symptomatology? A systematic review 

      Sæther, Sverre Georg; Schou, Morten Brix; Kondziella, Daniel (Journal article; Peer reviewed, 2017)
      Background:Patients with intracellular onconeural antibodies may present with neuro-psychiatric syndromes. Weaimed to evaluate the evidence for an association between well-characterized onconeural antibodies and ...