Blar i NTNU Open på forfatter "Ruprecht, Klemens"
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Epitope specificity of anti-synapsin autoantibodies: Differential targeting of synapsin I domains
Mertens, Robert; Melchert, Sarah; Gitler, Daniel; Schou, Morten Brix; Sæther, Sverre Georg; Vaaler, Arne; Piepgras, Johannes; Kochova, Elena; Benfenati, Fabio; Ahnert-Hilger, Gudrun; Ruprecht, Klemens; Höltje, Markus (Journal article; Peer reviewed, 2018)Objective To identify the specific domains of the presynaptic protein synapsin targeted by recently described autoantibodies to synapsin. Methods Sera of 20 and CSF of two patients with different psychiatric and ... -
Subtle Phenotype Differences in Psychiatric Patients With and Without Serum Immunoglobulin G Antibodies to Synapsin
Sæther, Sverre Georg; Vaaler, Arne; Evjenth, Anita; Aune, Therese Lie; Höltje, Markus; Ruprecht, Klemens; Schou, Morten Brix (Journal article; Peer reviewed, 2019)The discovery that antibodies targeting neuronal antigens can induce severe psychiatric symptoms has been a significant progress in the understanding of psychiatric disorders. Antibodies targeting synapsin I in serum and ...