Browsing NTNU Open by Author "Robbins, Hilary A."
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Absolute Risk of Oropharyngeal Cancer After an HPV16-E6 Serology Test and Potential Implications for Screening: Results From the Human Papillomavirus Cancer Cohort Consortium
Robbins, Hilary A.; Ferreiro-Iglesias, Aida; Waterboer, Tim; Brenner, Nicole; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Allan; Pawlita, Michael; D'Souza, Gypsyamber; Visvanathan, Kala; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley F.; Agalliu, Ilir; Wassertheil-Smoller, Sylvia; Ness-Jensen, Eivind; Hveem, Kristian; Grioni, Sara; Kaaks, Rudolf; Sánchez, Maria-Jose; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Huang, Wen-Yi; Freedman, Neal D.; Kreimer, Aimée R; Johansson, Mattias; Brennan, Paul (Peer reviewed; Journal article, 2022)PURPOSE Seropositivity for the HPV16-E6 oncoprotein is a promising marker for early detection of oropharyngeal cancer (OPC), but the absolute risk of OPC after a positive or negative test is unknown. METHODS We ... -
Assessment of Biomarker Testing for Lung Cancer Screening Eligibility
Larose, Tricia L; Meheus, Filip; Brennan, Paul; Johansson, Mattias; Robbins, Hilary A. (Journal article; Peer reviewed, 2020) -
The blood proteome of imminent lung cancer diagnosis
Albanes, Demetrius; Alcala, Karine; Alcala, Nicolas; Amos, Christopher I.; Arslan, Alan A.; Bassett, Julie K.; Brennan, Paul; Cai, Qiuyin; Chen, Chu; Feng, Xiaoshuang; Freedman, Neal D.; Guida, Florence; Hung, Rayjean J.; Hveem, Kristian; Johansson, Mikael; Johansson, Mattias; Koh, Woon-Puay; Langhammer, Arnulf; Milne, Roger L.; Muller, David; Onwuka, Justina; Sørgjerd, Elin Pettersen; Robbins, Hilary A.; Sesso, Howard D.; Severi, Gianluca; Shu, Xiao-Ou; Sieri, Sabina; Smith-Byrne, Karl; Stevens, Victoria; Tinker, Lesley; Tjønneland, Anne; Visvanathan, Kala; Wang, Ying; Wang, Renwei; Weinstein, Stephanie; Yuan, Jian-Min; Zahed, Hana; Zhang, Xuehong; Zheng, Wei (Peer reviewed; Journal article, 2023)Identification of risk biomarkers may enhance early detection of smoking-related lung cancer. We measured between 392 and 1,162 proteins in blood samples drawn at most three years before diagnosis in 731 smoking-matched ... -
A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium
Midttun, Øivind; Ulvik, Arve; Meyer, Klaus; Zahed, Hana; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Behndig, Annelie F.; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loïc; Weinstein, Stephanie J.; Cai, Qiuyin; Arslan, Alan A.; Chen, Yu; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Robbins, Hilary A.; Brennan, Paul; Johansson, Mattias; Ueland, Per Magne (Peer reviewed; Journal article, 2023)Circulating concentrations of metabolites (collectively called kynurenines) in the kynurenine pathway of tryptophan metabolism increase during inflammation, particularly in response to interferon-gamma (IFN-γ). Neopterin ... -
Epidemiology of 40 blood biomarkers of one-carbon metabolism, vitamin status, inflammation, and renal and endothelial function among cancer-free older adults
Zahed, Hana; Johansson, Mattias; Ueland, Per Magne; Midttun, Øivind; Milne, Roger L.; Giles, Graham G.; Manjer, Jonas; Sandsveden, Malte; Langhammer, Arnulf; Sørgjerd, Elin Pettersen; Grankvist, Kjell; Johansson, Mikael; Freedman, Neal D.; Huang, Wen-Yi; Chen, Chu; Prentice, Ross; Stevens, Victoria L.; Wang, Ying; Le Marchand, Loic; Wilkens, Lynne R.; Weinstein, Stephanie J.; Albanes, Demetrius; Cai, Qiuyin; Blot, William J.; Arslan, Alan A.; Zeleniuch-Jacquotte, Anne; Shu, Xiao-Ou; Zheng, Wei; Yuan, Jian-Min; Koh, Woon-Puay; Visvanathan, Kala; Sesso, Howard D.; Zhang, Xuehong; Gaziano, J. Michael; Fanidi, Anouar; Muller, David; Brennan, Paul; Guida, Florence; Robbins, Hilary A. (Peer reviewed; Journal article, 2021)Imbalances of blood biomarkers are associated with disease, and biomarkers may also vary non-pathologically across population groups. We described variation in concentrations of biomarkers of one-carbon metabolism, vitamin ... -
Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis
Feng, Xiaoshuang; Muller, David C.; Zahed, Hana; Alcala, Karine; Guida, Florence; Smith-Byrne, Karl; Yuan, Jian-Min; Koh, Woon-Puay; Wang, Renwei; Milne, Roger L.; Bassett, Julie K.; Langhammer, Arnulf; Hveem, Kristian; Stevens, Victoria L.; Wang, Ying; Johansson, Mikael; Tjønneland, Anne; Tumino, Rosario; Sheikh, Mahdi; Johansson, Mattias; Robbins, Hilary A. (Peer reviewed; Journal article, 2023)Background To evaluate whether circulating proteins are associated with survival after lung cancer diagnosis, and whether they can improve prediction of prognosis. Methods We measured up to 1159 proteins in blood ... -
Lung cancer risk discrimination of prediagnostic proteomics measurements compared with existing prediction tools
Feng, Xiaoshuang; Wu, Wendy Yi-Ying; Onwuka, Justina Ucheojor; Haider, Zahra; Alcala, Karine; Smith-Byrne, Karl; Zahed, Hana; Guida, Florence; Wang, Renwei; Bassett, Julie K.; Stevens, Victoria; Wang, Ying; Weinstein, Stephanie; Freedman, Neal D.; Chen, Chu; Tinker, Lesley; Nøst, Therese Haugdahl; Koh, Woon-Puay; Muller, David; Colorado-Yohar, Sandra M.; Tumino, Rosario; Hung, Rayjean J.; Amos, Christopher I.; Lin, Xihong; Zhang, Xuehong; Arslan, Alan A.; Sánchez, Maria-Jose; Sørgjerd, Elin Pettersen; Severi, Gianluca; Hveem, Kristian; Brennan, Paul; Langhammer, Arnulf; Milne, Roger L.; Yuan, Jian-Min; Melin, Beatrice; Johansson, Mikael; Robbins, Hilary A.; Johansson, Mattias (Peer reviewed; Journal article, 2023)Background We sought to develop a proteomics-based risk model for lung cancer and evaluate its risk-discriminatory performance in comparison with a smoking-based risk model (PLCOm2012) and a commercially available ... -
Timing of HPV16-E6 antibody seroconversion before OPSCC: Findings from the HPVC3 consortium
Kreimer, Aimée R.; Ferreiro-Iglesias, Aida; Nygård, Mari; Bender, Noemi; Schroeder, Lea; Hildesheim, Alan; Robbins, Hilary A.; Pawlita, Michael; Langseth, Hilde; Schlecht, Nicolas F.; Tinker, Lesley Fels; Agalliu, Ilir; Smoller, Sylvia W.; Ness-Jensen, Eivind; Hveem, Kristian; D'Souza, Gypsyamber; Visvanathan, Kala; May, Betty; Ursin, Giske; Weiderpass, Elisabete; Giles, Graham G.; Milne, Roger L.; Cai, Qiuyin; Blot, William J.; Zheng, Wei; Weinstein, Stephanie J.; Albanes, Demetrius; Brenner, Nicole; Hoffman-Bolton, Judith; Kaaks, Rudolf; Barricarte, Aurelio; Tjønneland, Anne; Sacerdote, Carlotta; Trichopoulou, Antonia; Vermeulen, Roel C.H.; Huang, Wen-Yi; Freedman, Neal D.; Brennan, Paul J.; Waterboer, Tim; Johansson, Mattias (Journal article; Peer reviewed, 2019)Background Human papillomavirus type 16 (HPV16)-E6 antibodies are detectable in peripheral blood before diagnosis in the majority of HPV16-driven oropharyngeal squamous cell carcinoma (OPSCC), but the timing of seroconversion ...