• Adiponectin prevents orthodontic tooth movement in rats 

      Haugen, Sigrid; Aasarød, Kristin Matre; Stunes, Astrid Kamilla; Mosti, Mats Peder; Franzen, Tanya Jeanette; Vandevska-Radunovic, Vaska; Syversen, Unni; Reseland, Janne Elin (Journal article; Peer reviewed, 2017)
      Objective The objective was to examine the effects of repetitive local administration of adiponectin on experimental tooth movement in rats. Materials and methods The maxillary right first molar of male Wistar rats ...
    • Adiponectin reduces bone stiffness; verified in a 3D artificial human bone model in vitro 

      Haugen, Sigrid; He, Jianying; Sundaresan, Alamelu; Stunes, Astrid Kamilla; Aasarød, Kristin Matre; Tiainen, Hanna; Syversen, Unni; Skallerud, Bjørn Helge; Reseland, Janne Elin (Journal article; Peer reviewed, 2018)
      Primary human osteoblasts and osteoclasts incubated in a rotating coculture system without any scaffolding material, form bone-like tissue that may be used to evaluate effects of various compounds on mechanical strength. ...
    • Skeletal effects of the saturated 3-thia fatty acid tetradecylthioacetic acid in rats 

      Stunes, Astrid Kamilla; Westbroek, Irene; Fossmark, Reidar; Berge, Rolf Kristian; Reseland, Janne Elin; Syversen, Unni (Journal article; Peer reviewed, 2011)
      This study explores the skeletal effects of the peroxisome proliferator activated receptor (PPAR)pan agonist tetradecylthioacetic acid (TTA). Rats, without (Study I) and with ovariectomy (OVX) or sham operation (Study II), ...
    • The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats 

      Stunes, Astrid Kamilla; Westbroek, Irene; Gustafsson, Björn; Fossmark, Reidar; Waarsing, Jan H; Eriksen, Erik Fink; Petzold, Christiane; Reseland, Janne Elin; Syversen, Unni (Journal article; Peer reviewed, 2011)
      Background Activation of peroxisome proliferator-activated receptor (PPAR)gamma is associated with bone loss and increased fracture risk, while PPARalpha activation seems to have positive skeletal effects. To further ...
    • Vitamin K2 modulates vitamin D induced mechanical properties of human 3D bone spheroids in vitro 

      Schröder, Maria; Riksen, Elisabeth Aurstad; He, Jianying; Skallerud, Bjørn Helge; Møller, Mona Elisabeth; Lian, Aina-Mari; Syversen, Unni; Reseland, Janne Elin (Peer reviewed; Journal article, 2020)
      Rotational culture promotes primary human osteoblasts (hOBs) to form three-dimensional (3D) multicellular spheroids with bone tissue-like structure without any scaffolding material. Cell-based bone models enable us to ...