• A short-activating RNA oligonucleotide targeting the islet β-cell transcriptional factor MafA in CD34(+) cells 

      Reebye, Vikash; Sætrom, Pål; Mintz, Paul J; Rossi, JJ; Kasahara, Noriyuki; Nteliopoulos, G; Nicholls, Joanna P; Haoudi, Abdelali; Gordon, Myrtle YA; Habib, Nagy A (Journal article; Peer reviewed, 2013)
      Upon functional loss of insulin producing islet β-cells, some patients with diabetes become dependent on life-long insulin supplementation therapy. Bioengineering surrogate insulin producing cells is an alternative replacement ...
    • Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile 

      Huang, Kai-Wen; Reebye, Vikash; Czysz, Katherine; Ciriello, Simona; Dorman, Stephanie; Reccia, Isabella; Lai, Hong-Shiee; Peng, Ling; Kostomitsopoulos, Nikos; Nicholls, Joanna; Habib, Robert; Tomalia, Donald A.; Sætrom, Pål; Wilkes, Edmund; Cutillas, Pedro; Rossi, John; Habib, Nagy (Peer reviewed; Journal article, 2020)
      Non-alcoholic fatty liver disease (NAFLD) culminates in insulin resistance and metabolic syndrome. Because there are no approved pharmacological treatment agents for non-alcoholic steatohepatitis (NASH) and NAFLD, different ...
    • MicroRNA-181a* Targets Nanog in a Subpopulation of CD34+ Cells Isolated From Peripheral Blood 

      Mintz, Paul J; Sætrom, Pål; Reebye, Vikash; Lundbæk, Marie Benner; Lao, Kaiqin; Rossi, John J; Gaensler, Karin ML; Kasahara, Noriyuki; Nicholls, Joanna P; Jensen, Steen; Haoudi, Abdelali; Emara, Mohamed M; Gordon, Myrtle YA; Habib, Nagy A (Journal article; Peer reviewed, 2012)
      Exploiting the properties of stem cells by microRNA (miRNA) profiling offers an attractive approach to identify new regulators of stem cell fate. Although numerous miRNA have been screened from hematopoietic stem cells ...